Janumet and Pruritus genital - a phase IV clinical study of FDA data


Pruritus genital is found among people who take Janumet, especially for people who are 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Janumet and have Pruritus genital. It is created by eHealthMe based on reports of 22,062 people who have side effects when taking Janumet from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Mar, 18, 2023

22,062 people reported to have side effects when taking Janumet.
Among them, 12 people (0.05%) have Pruritus genital.

What is Janumet?

Janumet has active ingredients of metformin hydrochloride; sitagliptin phosphate. It is often used in diabetes. eHealthMe is studying from 22,654 Janumet users for its effectiveness, alternative drugs and more.

What is Pruritus genital?

Pruritus genital (uneasy irritation of the skin of the vagina and the surrounding area) is found to be associated with 587 drugs and 327 conditions by eHealthMe.

Number of Janumet and Pruritus genital reports submitted per year:

Could Janumet cause Pruritus genital?

Time on Janumet when people have Pruritus genital *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Age of people who have Pruritus genital when taking Janumet *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 11.11 %
  • 40-49: 11.11 %
  • 50-59: 33.33 %
  • 60+: 44.44 %

Common drugs people take besides Janumet *:

  1. Betaderm: 2 people, 16.67%
  2. Cosentyx: 2 people, 16.67%
  3. Metformin: 2 people, 16.67%
  4. Tylenol: 2 people, 16.67%
  5. Zyrtec: 1 person, 8.33%
  6. Jardiance: 1 person, 8.33%
  7. Cymbalta: 1 person, 8.33%
  8. Dapagliflozin: 1 person, 8.33%
  9. Enalapril Maleate: 1 person, 8.33%
  10. Exelon: 1 person, 8.33%

Common side effects people have besides Pruritus genital *:

  1. Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 2 people, 16.67%
  2. Rashes (redness): 2 people, 16.67%
  3. Genital Rash (rash on sex organ): 2 people, 16.67%
  4. Itching: 2 people, 16.67%
  5. Fatigue (feeling of tiredness): 2 people, 16.67%
  6. Drug Hypersensitivity: 2 people, 16.67%
  7. High Blood Pressure: 2 people, 16.67%
  8. Calcinosis (calcium deposits in any soft tissue): 1 person, 8.33%
  9. Cerebral Small Vessel Ischaemic Disease (inadequate blood supply to small blood vessel of brain): 1 person, 8.33%
  10. Heart Palpitations (feelings or sensations that your heart is pounding or racing): 1 person, 8.33%

Common conditions people have *:

  1. Psoriasis (immune-mediated disease that affects the skin): 2 people, 16.67%
  2. Parkinson's Disease: 1 person, 8.33%
  3. Pain: 1 person, 8.33%
  4. Hypersensitivity: 1 person, 8.33%
  5. High Blood Pressure: 1 person, 8.33%
  6. High Blood Cholesterol: 1 person, 8.33%
  7. Blood Cholesterol Decreased: 1 person, 8.33%
  8. Bladder Disorder: 1 person, 8.33%
  9. Belching (release of gas from the digestive tract): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Janumet and have Pruritus genital?

Check whether Pruritus genital is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Pruritus genital and when was it recovered:

Expand to all the drugs that have ingredients of metformin hydrochloride; sitagliptin phosphate:

Alternative drugs to, pros and cons of Janumet:

Common Janumet side effects:

Browse all side effects of Janumet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Pruritus genital treatments and more:

COVID vaccines that are related to Pruritus genital:

All the drugs that are associated with Pruritus genital:

Common conditions associated with Pruritus genital:

All the conditions that are associated with Pruritus genital:

How the study uses the data?

The study uses data from the FDA. It is based on metformin hydrochloride; sitagliptin phosphate (the active ingredients of Janumet) and Janumet (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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