Januvia and High blood cholesterol - a phase IV clinical study of FDA data

Summary:

We study 69,623 people who have side effects when taking Januvia. High blood cholesterol is found, especially among people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take Metformin and have High blood pressure.

The phase IV clinical study analyzes which people take Januvia and have High blood cholesterol. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 26, 2023

69,623 people reported to have side effects when taking Januvia.
Among them, 597 people (0.86%) have High blood cholesterol.

What is Januvia?

Januvia has active ingredients of sitagliptin phosphate. It is used in diabetes. Currently, eHealthMe is studying from 70,777 Januvia users.

What is High blood cholesterol?

High blood cholesterol is found to be associated with 3,442 drugs and 3,480 conditions by eHealthMe. Currently, we are studying 453,578 people who have High blood cholesterol.

Number of Januvia and High blood cholesterol reports submitted per year:

Could Januvia cause High blood cholesterol?

* Approximation only. Some reports may have incomplete information.

Do you take Januvia and have High blood cholesterol?

Check whether High blood cholesterol is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Liao KF, Lin CL, Lai SW, Chen WC, "Sitagliptin use and risk of acute pancreatitis in type 2 diabetes mellitus: a population-based case-control study in Taiwan", European journal of internal medicine, 2016 Jan .
Belice T, Yuce S, Kizilkaya B, Kurt A, Cure E, "Noncardiac pulmonary edema induced by sitagliptin treatment", Journal of family medicine and primary care, 2014 Jan .
Misgar, R. A., Bhat, J. A., Wani, A. I., & Bashir, M. I., "Sitagliptin induced splenic infarcts", Clinical Diabetology, 2014 Jan .
Stricklin SM, Stoecker WV, Rader RK, Hood AF, Litt JZ, Schuman TP, "Persistent edematous-plaque photosensitivity observed with sitagliptin phosphate (Januvia?)", Dermatology online journal, 2012 Feb .

Related studies

Januvia side effects by duration, gender and age:

Januvia side effects (70,777 reports)

High blood cholesterol treatments and more:

High blood cholesterol (453,578 reports)

Common drugs associated with High blood cholesterol:

All the drugs that are associated with High blood cholesterol:

High blood cholesterol (3,442 drugs)

Common conditions associated with High blood cholesterol:

Rheumatoid arthritis: 9,579 reports
High blood pressure: 6,636 reports

All the conditions that are associated with High blood cholesterol:

High blood cholesterol (3,480 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sitagliptin phosphate (the active ingredients of Januvia) and Januvia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.