Keppra and Renal failure acute - a phase IV clinical study of FDA data

Summary:

We study 67,418 people who have side effects when taking Keppra. Renal failure acute is found, especially among people who are male, 60+ old, have been taking the drug for < 1 month, also take Zofran and have Convulsion.

The phase IV clinical study analyzes which people take Keppra and have Renal failure acute. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 30, 2023

67,418 people reported to have side effects when taking Keppra.
Among them, 271 people (0.4%) have Renal failure acute.

What is Keppra?

Keppra has active ingredients of levetiracetam. It is used in epilepsy. Currently, eHealthMe is studying from 70,558 Keppra users.

What is Renal failure acute?

Renal failure acute (rapid kidney dysfunction) is found to be associated with 3,072 drugs and 3,097 conditions by eHealthMe. Currently, we are studying 73,864 people who have Renal failure acute.

Number of Keppra and Renal failure acute reports submitted per year:

* Approximation only. Some reports may have incomplete information.

Do you take Keppra and have Renal failure acute?

Check whether Renal failure acute is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Schattner A, Al-Bewerat A, "Levetiracetam (Keppra), urinary retention and literature search", A fatty cause of renal failure; what is your diagnosis?, 2016 Oct .
Spengler DC, Montouris GD, Hohler AD, "Levetiracetam as a possible contributor to acute kidney injury", Clinical therapeutics, 2014 Aug .
Alokaily FA, Alghamdi M, Almalki AS, Alhussaini H, "Aspirin induced leukocytoclastic vasculitis, lower gastrointestinal hemorrhage and acute renal failure (mimicking systemic vasculitis)", Saudi medical journal, 2013 Apr .
Almeida DM, Jean MR, Chystsiakova A, Monahan E, Oliveira SB, Monteiro IM, "Levetiracetam-associated acute pancreatitis in an adolescent with autism: a case report", Pancreas, 2013 Jan .

Related studies

Keppra side effects by duration, gender and age:

Keppra side effects (70,558 reports)

Renal failure acute treatments and more:

Renal failure acute (73,864 reports)

Common drugs associated with Renal failure acute:

All the drugs that are associated with Renal failure acute:

Renal failure acute (3,072 drugs)

Common conditions associated with Renal failure acute:

High blood pressure: 6,913 reports
Type 2 diabetes: 3,046 reports
Diabetes: 2,594 reports
Pain: 2,373 reports
Atrial fibrillation/flutter: 2,264 reports
Multiple myeloma: 1,881 reports

All the conditions that are associated with Renal failure acute:

Renal failure acute (3,097 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on levetiracetam (the active ingredients of Keppra) and Keppra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.