Keytruda and Diarrhea haemorrhagic - a phase IV clinical study of FDA data


We study 45,936 people who have side effects when taking Keytruda. Diarrhea haemorrhagic is found, especially among people who are male, 60+ old, have been taking the drug for 1 - 6 months, also take Carboplatin and have Lung neoplasm malignant.

The phase IV clinical study analyzes which people take Keytruda and have Diarrhea haemorrhagic. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 26, 2023

45,936 people reported to have side effects when taking Keytruda.
Among them, 23 people (0.05%) have Diarrhea haemorrhagic.

What is Keytruda?

Keytruda has active ingredients of pembrolizumab. Currently, eHealthMe is studying from 46,022 Keytruda users.

What is Diarrhea haemorrhagic?

Diarrhea haemorrhagic is found to be associated with 1,408 drugs and 729 conditions by eHealthMe. Currently, we are studying 11,447 people who have Diarrhea haemorrhagic.

Number of Keytruda and Diarrhea haemorrhagic reports submitted per year:

Could Keytruda cause Diarrhea haemorrhagic?

Time on Keytruda when people have Diarrhea haemorrhagic *:

  • < 1 month: 36.36 %
  • 1 - 6 months: 45.45 %
  • 6 - 12 months: 18.18 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Diarrhea haemorrhagic when taking Keytruda *:

  • female: 47.83 %
  • male: 52.17 %

Age of people who have Diarrhea haemorrhagic when taking Keytruda *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 15.79 %
  • 50-59: 15.79 %
  • 60+: 68.42 %

Common drugs people take besides Keytruda *:

  1. Paclitaxel: 2 people, 8.70%
  2. Cyclophosphamide: 2 people, 8.70%
  3. Carboplatin: 2 people, 8.70%
  4. Xarelto: 1 person, 4.35%
  5. Vigamox: 1 person, 4.35%
  6. Ribavirin: 1 person, 4.35%
  7. Reclast: 1 person, 4.35%
  8. Pred Forte: 1 person, 4.35%
  9. Nexium: 1 person, 4.35%
  10. Imodium: 1 person, 4.35%

Common side effects people have besides Diarrhea haemorrhagic *:

  1. High Blood Pressure: 4 people, 17.39%
  2. Colitis (inflammation of colon): 3 people, 13.04%
  3. Hepatic Function Abnormal: 2 people, 8.70%
  4. Fatigue (feeling of tiredness): 2 people, 8.70%
  5. Blood Thyroid Stimulating Hormone Increased: 2 people, 8.70%
  6. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 2 people, 8.70%
  7. Chest Pain: 2 people, 8.70%
  8. Joint Pain: 2 people, 8.70%
  9. Muscle Aches (muscle pain): 2 people, 8.70%
  10. Dizziness: 2 people, 8.70%

Common conditions people have *:

  1. Lung Neoplasm Malignant (cancer tumour of lung): 3 people, 13.04%
  2. Lung Cancer - Non-Small Cell (lung cancer): 2 people, 8.70%
  3. Endometrial Neoplasm (tumour of uterus wall): 2 people, 8.70%
  4. Endometrial Cancer Stage Iii: 2 people, 8.70%
  5. Bronchial Carcinoma (lung cancer): 2 people, 8.70%
  6. Transitional Cell Carcinoma (cancer tumour inner most layer of urinary system): 1 person, 4.35%
  7. Renal Cell Carcinoma (a kidney cancer): 1 person, 4.35%
  8. Oesophageal Carcinoma (cancer tumour of oesophagus): 1 person, 4.35%
  9. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 1 person, 4.35%
  10. Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Keytruda and have Diarrhea haemorrhagic?

Check whether Diarrhea haemorrhagic is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Keytruda side effects by duration, gender and age:

Diarrhea haemorrhagic treatments and more:

Common drugs associated with Diarrhea haemorrhagic:

All the drugs that are associated with Diarrhea haemorrhagic:

Common conditions associated with Diarrhea haemorrhagic:

All the conditions that are associated with Diarrhea haemorrhagic:

How the study uses the data?

The study uses data from the FDA. It is based on pembrolizumab (the active ingredients of Keytruda) and Keytruda (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


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DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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