Lactulose and Metabolic encephalopathy - a phase IV clinical study of FDA data
Metabolic encephalopathy is found among people who take Lactulose, especially for people who are female, 60+ old, have been taking the drug for < 1 month.
The phase IV clinical study analyzes which people take Lactulose and have Metabolic encephalopathy. It is created by eHealthMe based on reports of 40,667 people who have side effects when taking Lactulose from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
40,667 people reported to have side effects when taking Lactulose.
Among them, 53 people (0.13%) have Metabolic encephalopathy.
What is Lactulose?
Lactulose has active ingredients of lactulose. It is often used in constipation. eHealthMe is studying from 40,907 Lactulose users for its effectiveness, alternative drugs and more.
What is Metabolic encephalopathy?
Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy) is found to be associated with 978 drugs and 551 conditions by eHealthMe.
Number of Lactulose and Metabolic encephalopathy reports submitted per year:
Time on Lactulose when people have Metabolic encephalopathy *:
- < 1 month: 100 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Metabolic encephalopathy when taking Lactulose *:
- female: 57.14 %
- male: 42.86 %
Age of people who have Metabolic encephalopathy when taking Lactulose *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 4.08 %
- 30-39: 4.08 %
- 40-49: 4.08 %
- 50-59: 22.45 %
- 60+: 65.31 %
Common drugs people take besides Lactulose *:
- Pantoprazole: 10 people, 18.87%
- Omeprazole: 8 people, 15.09%
- Revlimid: 7 people, 13.21%
- Lasix: 7 people, 13.21%
- Amlodipine: 6 people, 11.32%
- Seroquel: 6 people, 11.32%
- Baclofen: 6 people, 11.32%
- Valproic Acid: 6 people, 11.32%
- Norvasc: 5 people, 9.43%
- Xifaxan: 5 people, 9.43%
Common side effects people have besides Metabolic encephalopathy *:
- Hyperammonaemia: 9 people, 16.98%
- Anaemia (lack of blood): 8 people, 15.09%
- Thrombocytopenia (decrease of platelets in blood): 8 people, 15.09%
- Depressed Level Of Consciousness: 8 people, 15.09%
- Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 7 people, 13.21%
- Sepsis (a severe blood infection that can lead to organ failure and death): 7 people, 13.21%
- Mental Status Changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 7 people, 13.21%
- Blood Bilirubin Increased: 6 people, 11.32%
- Urinary Tract Infection: 6 people, 11.32%
- Abdominal Pain: 6 people, 11.32%
Common conditions people have *:
- Multiple Myeloma (cancer of the plasma cells): 8 people, 15.09%
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 6 people, 11.32%
- Pain: 5 people, 9.43%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 7.55%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 7.55%
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 7.55%
- High Blood Pressure: 4 people, 7.55%
- Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 3 people, 5.66%
- Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 5.66%
- Depression: 2 people, 3.77%
* Approximation only. Some reports may have incomplete information.
Do you take Lactulose and have Metabolic encephalopathy?Check whether Metabolic encephalopathy is associated with a drug or a condition
How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
How severe was Metabolic encephalopathy and when was it recovered:
Expand to all the drugs that have ingredients of lactulose:
Alternative drugs to, pros and cons of Lactulose:
- Lactulose (40,907 reports)
Common Lactulose side effects:
Browse all side effects of Lactulose:a b c d e f g h i j k l m n o p q r s t u v w x y z
Metabolic encephalopathy treatments and more:
- Metabolic encephalopathy (3,063 reports)
COVID vaccines that are related to Metabolic encephalopathy:
- Metabolic encephalopathy in Moderna COVID Vaccine
- Metabolic encephalopathy in Pfizer BioNTech Covid Vaccine
- Metabolic encephalopathy in Johnson and Johnson Covid Vaccine
Common drugs associated with Metabolic encephalopathy:
All the drugs that are associated with Metabolic encephalopathy:
- Metabolic encephalopathy (978 drugs)
Common conditions associated with Metabolic encephalopathy:
- Depression: 117 reports
- Hbp: 215 reports
- High blood pressure: 264 reports
- Hypertension aggravated: 270 reports
- Ms: 132 reports
- Multiple myeloma: 139 reports
- Multiple sclerosis: 141 reports
- Multiple sclerosis aggravated: 132 reports
- Pain: 188 reports
All the conditions that are associated with Metabolic encephalopathy:
- Metabolic encephalopathy (551 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on lactulose (the active ingredients of Lactulose) and Lactulose (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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