Lamictal and Drug exposure during pregnancy - a phase IV clinical study of FDA data

Summary:

We study 72,153 people who have side effects when taking Lamictal. Drug exposure during pregnancy is found, especially among people who are 30-39 old, have been taking the drug for 6 - 12 months, also take Folic acid and have Depression.

The phase IV clinical study analyzes which people take Lamictal and have Drug exposure during pregnancy. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 26, 2023

72,153 people reported to have side effects when taking Lamictal.
Among them, 1,489 people (2.06%) have Drug exposure during pregnancy.

What is Lamictal?

Lamictal has active ingredients of lamotrigine. It is used in bipolar disorder. Currently, eHealthMe is studying from 80,389 Lamictal users.

What is Drug exposure during pregnancy?

Drug exposure during pregnancy is found to be associated with 1,797 drugs and 1,489 conditions by eHealthMe. Currently, we are studying 58,630 people who have Drug exposure during pregnancy.

Number of Lamictal and Drug exposure during pregnancy reports submitted per year:

Could Lamictal cause Drug exposure during pregnancy?

* Approximation only. Some reports may have incomplete information.

Do you take Lamictal and have Drug exposure during pregnancy?

Check whether Drug exposure during pregnancy is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Alonso-Navarro H, Montes JM, Plaza-Nieto JF, Jiménez-Jiménez FJ, "Cataplexy Possibly Associated With Lamotrigine", Journal of clinical psychopharmacology, 2016 Aug .
Gupta MC, Khanna J, Mathur R, Mittal N, "Lamotrigine-induced fulminant hepatic failure: an unusual presentation", IMSEAR, 2015 Jan .

Related studies

Lamictal side effects by duration, gender and age:

Lamictal side effects (80,389 reports)

Drug exposure during pregnancy treatments and more:

Drug exposure during pregnancy (58,630 reports)

Common drugs associated with Drug exposure during pregnancy:

All the drugs that are associated with Drug exposure during pregnancy:

Drug exposure during pregnancy (1,797 drugs)

Common conditions associated with Drug exposure during pregnancy:

All the conditions that are associated with Drug exposure during pregnancy:

Drug exposure during pregnancy (1,489 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lamotrigine (the active ingredients of Lamictal) and Lamictal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.