Lamotrigine and Clonus - a phase IV clinical study of FDA data
We study 61,601 people who have side effects when taking Lamotrigine. Clonus is found, especially among people who are female, 20-29 old, have been taking the drug for < 1 month, also take Fluoxetine and have Upper respiratory tract infection.
The phase IV clinical study analyzes which people take Lamotrigine and have Clonus. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
61,601 people reported to have side effects when taking Lamotrigine.
Among them, 134 people (0.22%) have Clonus.
What is Lamotrigine?
Lamotrigine has active ingredients of lamotrigine. It is used in bipolar disorder. Currently, eHealthMe is studying from 71,306 Lamotrigine users.
What is Clonus?
Clonus (series of involuntary, rhythmic, muscular contractions and relaxations) is found to be associated with 891 drugs and 553 conditions by eHealthMe. Currently, we are studying 3,058 people who have Clonus.
Number of Lamotrigine and Clonus reports submitted per year:
Time on Lamotrigine when people have Clonus *:
Gender of people who have Clonus when taking Lamotrigine*:
Age of people who have Clonus when taking Lamotrigine *:
Common drugs people take besides Lamotrigine *:
Common side effects people have besides Clonus *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Lamotrigine and have Clonus?Check whether Clonus is associated with a drug or a condition
How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Alonso-Navarro H, Montes JM, Plaza-Nieto JF, Jiménez-Jiménez FJ, "Cataplexy Possibly Associated With Lamotrigine", Journal of clinical psychopharmacology, 2016 Aug .
- Gupta MC, Khanna J, Mathur R, Mittal N, "Lamotrigine-induced fulminant hepatic failure: an unusual presentation", IMSEAR, 2015 Jan .
Lamotrigine side effects by duration, gender and age:
- Lamotrigine side effects (71,306 reports)
Clonus treatments and more:
- Clonus (3,058 reports)
Common drugs associated with Clonus:
- Baclofen: 191 reports
- Lioresal: 182 reports
- Paroxetine: 153 reports
- Tramadol: 152 reports
- Escitalopram: 142 reports
- Lamotrigine: 134 reports
- Propofol: 119 reports
- Sertraline: 115 reports
All the drugs that are associated with Clonus:
- Clonus (891 drugs)
Common conditions associated with Clonus:
All the conditions that are associated with Clonus:
- Clonus (553 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on lamotrigine (the active ingredients of Lamotrigine) and Lamotrigine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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