Lamotrigine and Escherichia infection - a phase IV clinical study of FDA data

Summary:

Escherichia infection is found among people who take Lamotrigine, especially for people who are female, 30-39 old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Lamotrigine and have Escherichia infection. It is created by eHealthMe based on reports of 61,601 people who have side effects when taking Lamotrigine from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Oct, 04, 2022

61,601 people reported to have side effects when taking Lamotrigine.
Among them, 28 people (0.05%) have Escherichia infection.


What is Lamotrigine?

Lamotrigine has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 64,928 Lamotrigine users for its effectiveness, alternative drugs and more.

What is Escherichia infection?

Escherichia infection (bacterial infection by escherichia coli) is found to be associated with 1,330 drugs and 801 conditions by eHealthMe.

Number of Lamotrigine and Escherichia infection reports submitted per year:

Could Lamotrigine cause Escherichia infection?

Time on Lamotrigine when people have Escherichia infection *:

  • < 1 month: 66.67 %
  • 1 - 6 months: 33.33 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Escherichia infection when taking Lamotrigine *:

  • female: 70.37 %
  • male: 29.63 %

Age of people who have Escherichia infection when taking Lamotrigine *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 8.7 %
  • 20-29: 4.35 %
  • 30-39: 39.13 %
  • 40-49: 8.7 %
  • 50-59: 13.04 %
  • 60+: 26.09 %

Common drugs people take besides Lamotrigine *:

  1. Vicodin: 7 people, 25.00%
  2. Seroquel: 7 people, 25.00%
  3. Clonazepam: 6 people, 21.43%
  4. Marijuana: 5 people, 17.86%
  5. Flexeril: 5 people, 17.86%
  6. Topamax: 5 people, 17.86%
  7. Acetaminophen: 4 people, 14.29%
  8. Xanax: 4 people, 14.29%
  9. Excedrin: 4 people, 14.29%
  10. Paxil: 4 people, 14.29%

Common side effects people have besides Escherichia infection *:

  1. Urinary Tract Infection: 10 people, 35.71%
  2. Kidney Infection (Pyelonephritis): 9 people, 32.14%
  3. Fever: 6 people, 21.43%
  4. Sepsis (a severe blood infection that can lead to organ failure and death): 6 people, 21.43%
  5. Cellulitis (infection under the skin): 5 people, 17.86%
  6. Suicide Attempt: 5 people, 17.86%
  7. Abdominal Pain: 4 people, 14.29%
  8. Multiple Drug Overdose Intentional: 4 people, 14.29%
  9. Erythema Multiforme (a type of hypersensitivity reaction): 4 people, 14.29%
  10. Fall: 4 people, 14.29%

Common conditions people have *:

  1. Psoriasis (immune-mediated disease that affects the skin): 8 people, 28.57%
  2. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 3 people, 10.71%
  3. Metastases To Bone (cancer spreads to bone): 2 people, 7.14%
  4. Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 2 people, 7.14%
  5. Birth Control: 2 people, 7.14%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 7.14%
  7. Breast Cancer: 2 people, 7.14%
  8. Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 2 people, 7.14%
  9. Stress And Anxiety: 2 people, 7.14%
  10. Immunodeficiency Common Variable: 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Lamotrigine and have Escherichia infection?

Check whether Escherichia infection is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



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How severe was Escherichia infection and when was it recovered:

Expand to all the drugs that have ingredients of lamotrigine:

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Common Lamotrigine side effects:

Browse all side effects of Lamotrigine:

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Escherichia infection treatments and more:

COVID vaccines that are related to Escherichia infection:

Common drugs associated with Escherichia infection:

All the drugs that are associated with Escherichia infection:

Common conditions associated with Escherichia infection:

All the conditions that are associated with Escherichia infection:

How the study uses the data?

The study uses data from the FDA. It is based on lamotrigine (the active ingredients of Lamotrigine) and Lamotrigine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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