Lamotrigine and Primary intestinal pseudo-obstruction - a phase IV clinical study of FDA data
Primary intestinal pseudo-obstruction is found among people who take Lamotrigine, especially for people who are male, 40-49 old.
The phase IV clinical study analyzes which people take Lamotrigine and have Primary intestinal pseudo-obstruction. It is created by eHealthMe based on reports of 61,601 people who have side effects when taking Lamotrigine from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
61,601 people reported to have side effects when taking Lamotrigine.
Among them, 8 people (0.01%) have Primary intestinal pseudo-obstruction.
What is Lamotrigine?
Lamotrigine has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 65,013 Lamotrigine users for its effectiveness, alternative drugs and more.
What is Primary intestinal pseudo-obstruction?
Primary intestinal pseudo-obstruction (symptoms of intestinal blockage without any physical signs of a blockage) is found to be associated with 545 drugs and 439 conditions by eHealthMe.
Number of Lamotrigine and Primary intestinal pseudo-obstruction reports submitted per year:
Gender of people who have Primary intestinal pseudo-obstruction when taking Lamotrigine *:
- female: 37.5 %
- male: 62.5 %
Age of people who have Primary intestinal pseudo-obstruction when taking Lamotrigine *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 28.57 %
- 40-49: 42.86 %
- 50-59: 28.57 %
- 60+: 0.0 %
Common drugs people take besides Lamotrigine *:
- Lioresal: 2 people, 25.00%
- Morphine: 2 people, 25.00%
- Clobazam: 2 people, 25.00%
- Amlodipine: 2 people, 25.00%
- Tamsulosin: 2 people, 25.00%
- Primidone: 1 person, 12.50%
- Paracetamol: 1 person, 12.50%
- Stelara: 1 person, 12.50%
- Lyrica: 1 person, 12.50%
- Topiramate: 1 person, 12.50%
Common side effects people have besides Primary intestinal pseudo-obstruction *:
- Intestinal Obstruction: 3 people, 37.50%
- Sinus Tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 2 people, 25.00%
- Mallory-Weiss Syndrome (gastro-oesophageal laceration syndrome refers to bleeding from tears): 2 people, 25.00%
- Atelectasis (partial or complete collapse of the lung): 2 people, 25.00%
- Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 2 people, 25.00%
- Shunt Malfunction: 2 people, 25.00%
- Gastrostomy Failure (failure of surgically made opening in stomach): 2 people, 25.00%
- Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 2 people, 25.00%
- Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 2 people, 25.00%
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 25.00%
Common conditions people have *:
- Psoriasis (immune-mediated disease that affects the skin): 2 people, 25.00%
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1 person, 12.50%
- Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 12.50%
- Psychotic Disorder: 1 person, 12.50%
* Approximation only. Some reports may have incomplete information.
Do you take Lamotrigine and have Primary intestinal pseudo-obstruction?Check whether Primary intestinal pseudo-obstruction is associated with a drug or a condition
How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Alonso-Navarro H, Montes JM, Plaza-Nieto JF, Jiménez-Jiménez FJ, "Cataplexy Possibly Associated With Lamotrigine", Journal of clinical psychopharmacology, 2016 Aug .
- Gupta MC, Khanna J, Mathur R, Mittal N, "Lamotrigine-induced fulminant hepatic failure: an unusual presentation", IMSEAR, 2015 Jan .
How severe was Primary intestinal pseudo-obstruction and when was it recovered:
Expand to all the drugs that have ingredients of lamotrigine:
Alternative drugs to, pros and cons of Lamotrigine:
- Lamotrigine (65,013 reports)
Common Lamotrigine side effects:
- Drug ineffective: 4,944 reports
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3,463 reports
- Rashes (redness): 3,102 reports
- Dizziness: 2,881 reports
- Fatigue (feeling of tiredness): 2,878 reports
- Headache (pain in head): 2,487 reports
Browse all side effects of Lamotrigine:a b c d e f g h i j k l m n o p q r s t u v w x y z
Primary intestinal pseudo-obstruction treatments and more:
- Primary intestinal pseudo-obstruction (903 reports)
COVID vaccines that are related to Primary intestinal pseudo-obstruction:
- Primary intestinal pseudo-obstruction in Moderna COVID Vaccine
- Primary intestinal pseudo-obstruction in Pfizer BioNTech Covid Vaccine
- Primary intestinal pseudo-obstruction in Johnson and Johnson Covid Vaccine
Common drugs associated with Primary intestinal pseudo-obstruction:
- Morphine: 107 reports
All the drugs that are associated with Primary intestinal pseudo-obstruction:
- Primary intestinal pseudo-obstruction (545 drugs)
All the conditions that are associated with Primary intestinal pseudo-obstruction:
- Primary intestinal pseudo-obstruction (439 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on lamotrigine (the active ingredients of Lamotrigine) and Lamotrigine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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