Lariam and Cfs - a phase IV clinical study of FDA data
Summary:
Cfs is found among people who take Lariam, especially for people who are female, 10-19 old, have been taking the drug for 1 - 6 months.
The phase IV clinical study analyzes which people take Lariam and have Cfs. It is created by eHealthMe based on reports of 3,077 people who have side effects when taking Lariam from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
3,077 people reported to have side effects when taking Lariam.
Among them, 9 people (0.29%) have Cfs.
What is Lariam?
Lariam has active ingredients of mefloquine hydrochloride. It is often used in malaria. eHealthMe is studying from 3,139 Lariam users for its effectiveness, alternative drugs and more.
What is Cfs?
Cfs (chronic fatigue syndrome) is found to be associated with 1,034 drugs and 852 conditions by eHealthMe.
Number of Lariam and Cfs reports submitted per year:

Time on Lariam when people have Cfs *:
- < 1 month: 0.0 %
- 1 - 6 months: 100 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Cfs when taking Lariam *:
- female: 55.56 %
- male: 44.44 %
Age of people who have Cfs when taking Lariam *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 57.14 %
- 20-29: 14.29 %
- 30-39: 0.0 %
- 40-49: 28.57 %
- 50-59: 0.0 %
- 60+: 0.0 %
Common drugs people take besides Lariam *:
- Zoloft: 2 people, 22.22%
Common side effects people have besides Cfs *:
- Memory Loss: 8 people, 88.89%
- Depression: 7 people, 77.78%
- Headache (pain in head): 7 people, 77.78%
- Confusion: 6 people, 66.67%
- Constipation: 6 people, 66.67%
- Tinnitus (a ringing in the ears): 6 people, 66.67%
- Dry Mouth: 6 people, 66.67%
- Dry Skin: 6 people, 66.67%
- Nausea (feeling of having an urge to vomit): 6 people, 66.67%
- Fatigue (feeling of tiredness): 5 people, 55.56%
Common conditions people have *:
- Depression: 1 person, 11.11%
* Approximation only. Some reports may have incomplete information.
Do you take Lariam and have Cfs?
Check whether Cfs is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Cfs and when was it recovered:
Expand to all the drugs that have ingredients of mefloquine hydrochloride:
Alternative drugs to, pros and cons of Lariam:
- Lariam (3,139 reports)
Common Lariam side effects:
- Abnormal behavior: 107 reports
- Abnormal dreams: 185 reports
- Aggression: 139 reports
- Agitation (state of anxiety or nervous excitement): 230 reports
- Balance disorder: 141 reports
- Breathing difficulty: 103 reports
- Chest pain: 158 reports
- Chills (felling of cold): 103 reports
- Confusion: 201 reports
- Confusional state: 115 reports
- Depression: 603 reports
- Diarrhea: 273 reports
- Disturbance in attention: 259 reports
- Dizziness: 243 reports
- Fatigue (feeling of tiredness): 415 reports
- Fever: 227 reports
- Hallucinations (sensations that appear real but are created by your mind): 236 reports
- Headache (pain in head): 387 reports
- Heart palpitations (feelings or sensations that your heart is pounding or racing): 128 reports
- High blood pressure: 105 reports
- Hypoaesthesia (reduced sense of touch or sensation): 135 reports
- Insomnia (sleeplessness): 281 reports
- Joint pain: 102 reports
- Malaise (a feeling of general discomfort or uneasiness): 144 reports
- Memory loss: 281 reports
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 119 reports
- Mood swings (an extreme or rapid change in mood): 147 reports
- Muscle aches (muscle pain): 110 reports
- Nausea (feeling of having an urge to vomit): 316 reports
- Nightmares (unpleasant dreams): 209 reports
- Panic disorder: 327 reports
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 210 reports
- Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur): 228 reports
- Psychotic disorder: 249 reports
- Stress and anxiety: 348 reports
- Suicidal ideation: 258 reports
- Tinnitus (a ringing in the ears): 219 reports
- Tremor (trembling or shaking movements in one or more parts of your body): 201 reports
- Vestibular disorder (disorders of the body's balance (vestibular) system in the inner ear): 109 reports
- Vision blurred: 121 reports
- Visual disturbance: 135 reports
- Weakness: 246 reports
- Weight decreased: 120 reports
Browse all side effects of Lariam:
a b c d e f g h i j k l m n o p q r s t u v w x y zCfs treatments and more:
- Cfs (4,827 reports)
COVID vaccines that are related to Cfs:
- Cfs in Moderna COVID Vaccine
- Cfs in Pfizer BioNTech Covid Vaccine
- Cfs in Johnson and Johnson Covid Vaccine
Common drugs associated with Cfs:
All the drugs that are associated with Cfs:
- Cfs (1,034 drugs)
Common conditions associated with Cfs:
- Acne: 177 reports
- Acne aggravated: 177 reports
- Acne vulgaris: 177 reports
- Blood pressure - high: 101 reports
- Cystic acne: 177 reports
- Depression: 107 reports
- Hbp: 101 reports
- High blood pressure: 101 reports
- Hypertension: 101 reports
- Hypertension aggravated: 102 reports
- Pain: 120 reports
- Pain exacerbated: 120 reports
- Pain relief: 119 reports
- Pain relief by acupuncture: 120 reports
- Pimples: 177 reports
- Zits: 177 reports
All the conditions that are associated with Cfs:
- Cfs (852 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on mefloquine hydrochloride (the active ingredients of Lariam) and Lariam (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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