Leflunomide and Fatigue - a phase IV clinical study of FDA data
Summary:
We study 72,488 people who have side effects when taking Leflunomide. Fatigue is found, especially among people who are female, 40-49 old, have been taking the drug for 1 - 6 months, also take Enbrel and have Psoriatic arthropathy.
The phase IV clinical study analyzes which people take Leflunomide and have Fatigue. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
72,488 people reported to have side effects when taking Leflunomide.
Among them, 11,212 people (15.47%) have Fatigue.
What is Leflunomide?
Leflunomide has active ingredients of leflunomide. It is used in rheumatoid arthritis. Currently, eHealthMe is studying from 76,654 Leflunomide users.
What is Fatigue?
Fatigue (feeling of tiredness) is found to be associated with 5,404 drugs and 6,221 conditions by eHealthMe. Currently, we are studying 905,049 people who have Fatigue.
Number of Leflunomide and Fatigue reports submitted per year:
Time on Leflunomide when people have Fatigue *:
Gender of people who have Fatigue when taking Leflunomide*:
Age of people who have Fatigue when taking Leflunomide *:
Common drugs people take besides Leflunomide *:
Common side effects people have besides Fatigue *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Leflunomide and have Fatigue?
Check whether Fatigue is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Peel MM, Cooke M, Lewis-Peel HJ, Lea RA, Moyle W, "A randomized controlled trial of coenzyme Q 10 for fatigue in the late-onset sequelae of poliomyelitis", Complementary therapies in medicine, 2015 Dec .
Related studies
Leflunomide side effects by duration, gender and age:
- Leflunomide side effects (76,654 reports)
Fatigue treatments and more:
- Fatigue (905,049 reports)
Common drugs associated with Fatigue:
- Prednisone: 46,071 reports
- Methotrexate: 42,271 reports
- Aspirin: 41,687 reports
- Humira: 38,407 reports
- Enbrel: 32,387 reports
- Revlimid: 23,683 reports
- Vitamin d: 23,634 reports
- Tysabri: 23,185 reports
- Lisinopril: 23,114 reports
- Amlodipine: 22,987 reports
All the drugs that are associated with Fatigue:
- Fatigue (5,404 drugs)
Common conditions associated with Fatigue:
- Multiple sclerosis: 66,133 reports
- Rheumatoid arthritis: 50,897 reports
- Multiple myeloma: 30,410 reports
- High blood pressure: 29,311 reports
- Pain: 21,635 reports
- Depression: 21,501 reports
All the conditions that are associated with Fatigue:
- Fatigue (6,221 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on leflunomide (the active ingredients of Leflunomide) and Leflunomide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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