Letrozole and Ocular hyperaemia - a phase IV clinical study of FDA data


Ocular hyperaemia is found among people who take Letrozole, especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months.

The phase IV clinical study analyzes which people take Letrozole and have Ocular hyperaemia. It is created by eHealthMe based on reports of 39,784 people who have side effects when taking Letrozole from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Oct, 08, 2022

39,784 people reported to have side effects when taking Letrozole.
Among them, 57 people (0.14%) have Ocular hyperaemia.

What is Letrozole?

Letrozole has active ingredients of letrozole. It is often used in breast cancer. eHealthMe is studying from 40,306 Letrozole users for its effectiveness, alternative drugs and more.

What is Ocular hyperaemia?

Ocular hyperaemia (an abnormally large amount of blood in eye) is found to be associated with 1,844 drugs and 1,410 conditions by eHealthMe.

Number of Letrozole and Ocular hyperaemia reports submitted per year:

Could Letrozole cause Ocular hyperaemia?

Time on Letrozole when people have Ocular hyperaemia *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 83.33 %
  • 6 - 12 months: 16.67 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Ocular hyperaemia when taking Letrozole *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Ocular hyperaemia when taking Letrozole *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 10.26 %
  • 40-49: 20.51 %
  • 50-59: 41.03 %
  • 60+: 28.21 %

Common drugs people take besides Letrozole *:

  1. Ibrance: 14 people, 24.56%
  2. Zometa: 14 people, 24.56%
  3. Kisqali: 13 people, 22.81%
  4. Zoledronic Acid: 9 people, 15.79%
  5. Morphine: 6 people, 10.53%
  6. Amlodipine: 6 people, 10.53%
  7. Zoladex: 5 people, 8.77%
  8. Celebrex: 5 people, 8.77%
  9. Rebif: 5 people, 8.77%
  10. Medrol: 5 people, 8.77%

Common side effects people have besides Ocular hyperaemia *:

  1. Dizziness: 31 people, 54.39%
  2. Rashes (redness): 27 people, 47.37%
  3. Itching: 27 people, 47.37%
  4. Pain In Extremity: 26 people, 45.61%
  5. Influenza Like Illness: 24 people, 42.11%
  6. Joint Pain: 23 people, 40.35%
  7. Lacrimation Increased: 22 people, 38.60%
  8. Constipation: 21 people, 36.84%
  9. Fatigue (feeling of tiredness): 21 people, 36.84%
  10. Diarrhea: 21 people, 36.84%

Common conditions people have *:

  1. Muscle Spasms (muscle contraction): 8 people, 14.04%
  2. High Blood Pressure: 7 people, 12.28%
  3. Itching: 6 people, 10.53%
  4. Chest Pain: 5 people, 8.77%
  5. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 5 people, 8.77%
  6. Osteopenia (a condition where bone mineral density is lower than normal): 5 people, 8.77%
  7. Bone Disorder: 5 people, 8.77%
  8. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 8.77%
  9. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 5 people, 8.77%
  10. Depression: 5 people, 8.77%

* Approximation only. Some reports may have incomplete information.

Do you take Letrozole and have Ocular hyperaemia?

Check whether Ocular hyperaemia is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Ocular hyperaemia and when was it recovered:

Expand to all the drugs that have ingredients of letrozole:

Alternative drugs to, pros and cons of Letrozole:

Common Letrozole side effects:

Browse all side effects of Letrozole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Ocular hyperaemia treatments and more:

COVID vaccines that are related to Ocular hyperaemia:

Common drugs associated with Ocular hyperaemia:

All the drugs that are associated with Ocular hyperaemia:

Common conditions associated with Ocular hyperaemia:

All the conditions that are associated with Ocular hyperaemia:

How the study uses the data?

The study uses data from the FDA. It is based on letrozole (the active ingredients of Letrozole) and Letrozole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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