Levoleucovorin calcium and Hepatitis - a phase IV clinical study of FDA data


Hepatitis is found among people who take Levoleucovorin calcium, especially for people who are female, 60+ old.

The phase IV clinical study analyzes which people take Levoleucovorin calcium and have Hepatitis. It is created by eHealthMe based on reports of 1,216 people who have side effects when taking Levoleucovorin calcium from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Aug, 16, 2022

1,216 people reported to have side effects when taking Levoleucovorin calcium.
Among them, 15 people (1.23%) have Hepatitis.

What is Levoleucovorin calcium?

Levoleucovorin calcium has active ingredients of levoleucovorin calcium. eHealthMe is studying from 1,216 Levoleucovorin calcium users for its effectiveness, alternative drugs and more.

What is Hepatitis?

Hepatitis (inflammation of the liver) is found to be associated with 1,917 drugs and 1,468 conditions by eHealthMe.

Number of Levoleucovorin calcium and Hepatitis reports submitted per year:

Could Levoleucovorin calcium cause Hepatitis?

Gender of people who have Hepatitis when taking Levoleucovorin calcium *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Hepatitis when taking Levoleucovorin calcium *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 46.67 %
  • 60+: 53.33 %

Common drugs people take besides Levoleucovorin calcium *:

  1. Oxaliplatin: 8 people, 53.33%
  2. Orencia: 7 people, 46.67%
  3. Fluorouracil: 7 people, 46.67%
  4. Actemra: 7 people, 46.67%
  5. Prednisolone: 1 person, 6.67%

Common side effects people have besides Hepatitis *:

  1. Weight Decreased: 7 people, 46.67%
  2. Nausea (feeling of having an urge to vomit): 7 people, 46.67%
  3. Gingival Bleeding (bleeding gums): 7 people, 46.67%
  4. Headache (pain in head): 7 people, 46.67%
  5. High Blood Pressure: 7 people, 46.67%
  6. Indigestion: 7 people, 46.67%
  7. Vaginal Infection: 7 people, 46.67%
  8. Migraine (headache): 7 people, 46.67%
  9. Body Temperature Decreased: 7 people, 46.67%
  10. Oedema Peripheral (superficial swelling): 7 people, 46.67%

Common conditions people have *:

  1. Colon Cancer: 8 people, 53.33%
  2. Vaginal Infection: 7 people, 46.67%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 46.67%
  4. Interstitial Lung Disease: 1 person, 6.67%
  5. Hepatocellular Carcinoma (liver cancer): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Levoleucovorin calcium and have Hepatitis?

Check whether Hepatitis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

How severe was Hepatitis and when was it recovered:

Expand to all the drugs that have ingredients of levoleucovorin calcium:

Alternative drugs to, pros and cons of Levoleucovorin calcium:

Hepatitis treatments and more:

COVID vaccines that are related to Hepatitis:

Common drugs associated with Hepatitis:

All the drugs that are associated with Hepatitis:

Common conditions associated with Hepatitis:

All the conditions that are associated with Hepatitis:

How the study uses the data?

The study uses data from the FDA. It is based on levoleucovorin calcium (the active ingredients of Levoleucovorin calcium) and Levoleucovorin calcium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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