Lialda and Metabolic acidosis - a phase IV clinical study of FDA data

Summary:

Metabolic acidosis is reported only by a few people who take Lialda.

The phase IV clinical study analyzes which people take Lialda and have Metabolic acidosis. It is created by eHealthMe based on reports of 9,133 people who have side effects while taking Lialda from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Dec, 07, 2022

9,133 people reported to have side effects when taking Lialda.
Among them, 4 people (0.04%) have Metabolic acidosis.


What is Lialda?

Lialda has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 9,502 Lialda users for its effectiveness, alternative drugs and more.

What is Metabolic acidosis?

Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body) is found to be associated with 2,047 drugs and 1,584 conditions by eHealthMe.

Number of Lialda and Metabolic acidosis reports submitted per year:

Could Lialda cause Metabolic acidosis?

Common drugs people take besides Lialda *:

  1. Ambien: 2 people, 50.00%
  2. Vancomycin: 2 people, 50.00%
  3. Rowasa: 2 people, 50.00%
  4. Benicar: 2 people, 50.00%
  5. Lomotil: 1 person, 25.00%
  6. Amlodipine: 1 person, 25.00%
  7. Azor: 1 person, 25.00%
  8. Benicar Hct: 1 person, 25.00%
  9. Cimzia: 1 person, 25.00%
  10. Fish Oil: 1 person, 25.00%

Common side effects people have besides Metabolic acidosis *:

  1. Stress And Anxiety: 2 people, 50.00%
  2. Pancreatitis (inflammation of pancreas): 2 people, 50.00%
  3. Diverticulum Intestinal (a pouch that is attached to the first part of the small intestine): 2 people, 50.00%
  4. Gastric Polyps (abnormal growth of stomach tissue projecting from a mucous membrane): 1 person, 25.00%
  5. Aseptic Necrosis (the death of bone tissue due to a lack of blood supply): 1 person, 25.00%
  6. Barrett's Oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach): 1 person, 25.00%
  7. Breathing Difficulty: 1 person, 25.00%
  8. Celiac Disease - Sprue (a disease of the small intestine): 1 person, 25.00%
  9. Clostridium Difficile Colitis (inflammation of colon by clostridium difficile bacteria infection): 1 person, 25.00%
  10. Constipation: 1 person, 25.00%

Common conditions people have *:

  1. High Blood Pressure: 2 people, 50.00%
  2. Vitamin B12 Deficiency: 1 person, 25.00%
  3. Nausea (feeling of having an urge to vomit): 1 person, 25.00%
  4. Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 25.00%
  5. High Blood Cholesterol: 1 person, 25.00%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 25.00%
  7. Erection Problems: 1 person, 25.00%
  8. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 25.00%

* Approximation only. Some reports may have incomplete information.

Do you take Lialda and have Metabolic acidosis?

Check whether Metabolic acidosis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related publications that referenced our studies

Related studies

How severe was Metabolic acidosis and when was it recovered:

Expand to all the drugs that have ingredients of mesalamine:

Alternative drugs to, pros and cons of Lialda:

Common Lialda side effects:

Browse all side effects of Lialda:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Metabolic acidosis treatments and more:

COVID vaccines that are related to Metabolic acidosis:

Common drugs associated with Metabolic acidosis:

All the drugs that are associated with Metabolic acidosis:

Common conditions associated with Metabolic acidosis:

All the conditions that are associated with Metabolic acidosis:

How the study uses the data?

The study uses data from the FDA. It is based on mesalamine (the active ingredients of Lialda) and Lialda (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe: