Lioresal and Decreased activity - a phase IV clinical study of FDA data


Decreased activity is found among people who take Lioresal, especially for people who are male, 50-59 old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Lioresal and have Decreased activity. It is created by eHealthMe based on reports of 19,812 people who have side effects when taking Lioresal from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Oct, 02, 2022

19,812 people reported to have side effects when taking Lioresal.
Among them, 14 people (0.07%) have Decreased activity.

What is Lioresal?

Lioresal has active ingredients of baclofen. It is often used in multiple sclerosis. eHealthMe is studying from 19,861 Lioresal users for its effectiveness, alternative drugs and more.

What is Decreased activity?

Decreased activity is found to be associated with 2,208 drugs and 1,201 conditions by eHealthMe.

Number of Lioresal and Decreased activity reports submitted per year:

Could Lioresal cause Decreased activity?

Time on Lioresal when people have Decreased activity *:

  • < 1 month: 66.67 %
  • 1 - 6 months: 33.33 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Decreased activity when taking Lioresal *:

  • female: 46.15 %
  • male: 53.85 %

Age of people who have Decreased activity when taking Lioresal *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 9.09 %
  • 20-29: 18.18 %
  • 30-39: 18.18 %
  • 40-49: 9.09 %
  • 50-59: 36.36 %
  • 60+: 9.09 %

Common drugs people take besides Lioresal *:

  1. Zyrtec: 2 people, 14.29%
  2. Reglan: 2 people, 14.29%
  3. Methocarbamol: 2 people, 14.29%
  4. Hydrocodone Bitartrate And Acetaminophen: 2 people, 14.29%
  5. Plavix: 2 people, 14.29%
  6. Depakene: 2 people, 14.29%
  7. Primidone: 2 people, 14.29%
  8. Vyvanse: 2 people, 14.29%
  9. Ativan: 1 person, 7.14%
  10. Fluoxetine: 1 person, 7.14%

Common side effects people have besides Decreased activity *:

  1. Weakness: 4 people, 28.57%
  2. Overdose: 4 people, 28.57%
  3. Pain: 3 people, 21.43%
  4. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 3 people, 21.43%
  5. Respiratory Rate Decreased (less breathing rate/min): 2 people, 14.29%
  6. Hypokinesia (decreased bodily movement): 2 people, 14.29%
  7. Hypopnea: 2 people, 14.29%
  8. Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions): 2 people, 14.29%
  9. Fatigue (feeling of tiredness): 2 people, 14.29%
  10. Dyskinesia (abnormality or impairment of voluntary movement): 2 people, 14.29%

Common conditions people have *:

  1. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 7 people, 50.00%
  2. High Blood Pressure: 2 people, 14.29%
  3. High Blood Cholesterol: 2 people, 14.29%
  4. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 2 people, 14.29%
  5. Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 7.14%
  6. Back Pain: 1 person, 7.14%
  7. Bacterial Infection: 1 person, 7.14%
  8. Bipolar Disorder (mood disorder): 1 person, 7.14%
  9. Cerebral Palsy: 1 person, 7.14%
  10. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Lioresal and have Decreased activity?

Check whether Decreased activity is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Decreased activity and when was it recovered:

Expand to all the drugs that have ingredients of baclofen:

Alternative drugs to, pros and cons of Lioresal:

Common Lioresal side effects:

Browse all side effects of Lioresal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Decreased activity treatments and more:

COVID vaccines that are related to Decreased activity:

Common drugs associated with Decreased activity:

All the drugs that are associated with Decreased activity:

Common conditions associated with Decreased activity:

All the conditions that are associated with Decreased activity:

How the study uses the data?

The study uses data from the FDA. It is based on baclofen (the active ingredients of Lioresal) and Lioresal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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