Lioresal and Xerophthalmia - a phase IV clinical study of FDA data


Xerophthalmia is reported only by a few people who take Lioresal.

The phase IV clinical study analyzes which people take Lioresal and have Xerophthalmia. It is created by eHealthMe based on reports of 19,315 people who have side effects while taking Lioresal from the FDA, and is updated regularly.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On Jul, 15, 2022

19,315 people reported to have side effects when taking Lioresal.
Among them, 1 person (0.01%) has Xerophthalmia.

What is Lioresal?

Lioresal has active ingredients of baclofen. It is often used in multiple sclerosis. eHealthMe is studying from 19,364 Lioresal users for its effectiveness, alternative drugs and more.

What is Xerophthalmia?

Xerophthalmia (eye fails to produce tears) is found to be associated with 877 drugs and 602 conditions by eHealthMe.

Number of Lioresal and Xerophthalmia reports submitted per year:

Could Lioresal cause Xerophthalmia?

Gender of people who have Xerophthalmia when taking Lioresal *:

  • female: 0.0 %
  • male: 100 %

Age of people who have Xerophthalmia when taking Lioresal *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

Common drugs people take besides Lioresal *:

  1. Ditropan: 1 person, 100.00%
  2. Botox: 1 person, 100.00%

Common side effects people have besides Xerophthalmia *:

  1. Glossitis (infection of tongue with soreness): 1 person, 100.00%
  2. Fainting (loss of consciousness and postural tone): 1 person, 100.00%
  3. Dry Mouth: 1 person, 100.00%
  4. Arrhythmias (irregular heartbeat): 1 person, 100.00%

Common conditions people have *:

  1. Neurogenic Bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion): 1 person, 100.00%

* Approximation only. Some reports may have incomplete information.

Do you take Lioresal and have Xerophthalmia?

Check whether Xerophthalmia is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Alternative drugs to, pros and cons of Lioresal:

Xerophthalmia treatments and more:

COVID vaccines that are related to Xerophthalmia:

How severe was Xerophthalmia and when was it recovered:

Expand to all the drugs that have ingredients of baclofen:

All the drugs that are associated with Xerophthalmia:

All the conditions that are associated with Xerophthalmia:

How the study uses the data?

The study uses data from the FDA. It is based on baclofen (the active ingredients of Lioresal) and Lioresal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe: