Liothyronine sodium and Weight loss - a phase IV clinical study of FDA data


We study 3,359 people who have side effects when taking Liothyronine sodium. Weight loss is found, especially among people who are female, 60+ old, have been taking the drug for 5 - 10 years, also take Synthroid and have Narcolepsy.

The phase IV clinical study analyzes which people take Liothyronine sodium and have Weight loss. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 28, 2023

3,359 people reported to have side effects when taking Liothyronine sodium.
Among them, 15 people (0.45%) have Weight loss.

What is Liothyronine sodium?

Liothyronine sodium has active ingredients of liothyronine sodium. It is used in hypothyroidism. Currently, eHealthMe is studying from 3,798 Liothyronine sodium users.

What is Weight loss?

Weight loss is found to be associated with 2,577 drugs and 2,224 conditions by eHealthMe. Currently, we are studying 55,836 people who have Weight loss.

Number of Liothyronine sodium and Weight loss reports submitted per year:

Could Liothyronine sodium cause Weight loss?

Time on Liothyronine sodium when people have Weight loss *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 100 %
  • 10+ years: 0.0 %

Gender of people who have Weight loss when taking Liothyronine sodium *:

  • female: 86.67 %
  • male: 13.33 %

Age of people who have Weight loss when taking Liothyronine sodium *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 10 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 10 %
  • 60+: 80 %

Common drugs people take besides Liothyronine sodium *:

  1. Xyrem: 4 people, 26.67%
  2. Synthroid: 4 people, 26.67%
  3. Singulair: 3 people, 20.00%
  4. Pantoprazole: 2 people, 13.33%
  5. Proair Hfa: 2 people, 13.33%
  6. Glumetza: 2 people, 13.33%
  7. Escitalopram: 2 people, 13.33%
  8. Hydrocortisone Sodium Succinate: 2 people, 13.33%
  9. Lantus: 2 people, 13.33%
  10. Cyclobenzaprine Hydrochloride: 2 people, 13.33%

Common side effects people have besides Weight loss *:

  1. Oedema (fluid collection in tissue): 5 people, 33.33%
  2. Heart Rate Decreased: 4 people, 26.67%
  3. Body Temperature Decreased: 4 people, 26.67%
  4. Hair Loss: 4 people, 26.67%
  5. Feeling Cold: 4 people, 26.67%
  6. Hypotension (abnormally low blood pressure): 4 people, 26.67%
  7. Malaise (a feeling of general discomfort or uneasiness): 4 people, 26.67%
  8. Cataract (clouding of the lens inside the eye): 4 people, 26.67%
  9. Cardiac Failure: 4 people, 26.67%
  10. Breathing Difficulty: 4 people, 26.67%

Common conditions people have *:

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 33.33%
  2. Drowsiness: 3 people, 20.00%
  3. Type 2 Diabetes: 2 people, 13.33%
  4. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 13.33%
  5. Sleep Disorder: 1 person, 6.67%
  6. Seasonal Allergy (allergic condition due to certain season): 1 person, 6.67%
  7. Neck Injury: 1 person, 6.67%
  8. Mania (a state of abnormally elevated or irritable mood): 1 person, 6.67%
  9. Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 1 person, 6.67%
  10. Gastric Ulcer (stomach ulcer): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Liothyronine sodium and have Weight loss?

Check whether Weight loss is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Liothyronine sodium side effects by duration, gender and age:

Weight loss treatments and more:

Common drugs associated with Weight loss:

All the drugs that are associated with Weight loss:

Common conditions associated with Weight loss:

All the conditions that are associated with Weight loss:

How the study uses the data?

The study uses data from the FDA. It is based on liothyronine sodium (the active ingredients of Liothyronine sodium) and Liothyronine sodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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