Lisinopril and Drug level above therapeutic - a phase IV clinical study of FDA data

Summary:

We study 331,454 people who have side effects when taking Lisinopril. Drug level above therapeutic is found, especially among people who are male, 60+ old, have been taking the drug for < 1 month, also take Omeprazole and have Type 2 diabetes.

The phase IV clinical study analyzes which people take Lisinopril and have Drug level above therapeutic. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 30, 2023

331,454 people reported to have side effects when taking Lisinopril.
Among them, 68 people (0.02%) have Drug level above therapeutic.

What is Lisinopril?

Lisinopril has active ingredients of lisinopril. It is used in high blood pressure. Currently, eHealthMe is studying from 345,933 Lisinopril users.

What is Drug level above therapeutic?

Drug level above therapeutic is found to be associated with 759 drugs and 387 conditions by eHealthMe. Currently, we are studying 5,397 people who have Drug level above therapeutic.

Number of Lisinopril and Drug level above therapeutic reports submitted per year:

Could Lisinopril cause Drug level above therapeutic?

Time on Lisinopril when people have Drug level above therapeutic *:

Gender of people who have Drug level above therapeutic when taking Lisinopril *:

female: 36.36 %
male: 63.64 %

Age of people who have Drug level above therapeutic when taking Lisinopril *:

Common drugs people take besides Lisinopril *:

Common side effects people have besides Drug level above therapeutic *:

Lactic Acidosis (low ph in body tissues): 15 people, 22.06%
Nausea (feeling of having an urge to vomit): 13 people, 19.12%
Dehydration (dryness resulting from the removal of water): 10 people, 14.71%
Blood Glucose Increased: 10 people, 14.71%
Diarrhea: 10 people, 14.71%
Blood Creatinine Increased: 9 people, 13.24%
Hypotension (abnormally low blood pressure): 9 people, 13.24%
Weakness: 8 people, 11.76%
Nausea And Vomiting: 8 people, 11.76%
Unresponsive To Stimuli: 7 people, 10.29%

Common conditions people have *:

Type 2 Diabetes: 10 people, 14.71%
Stress And Anxiety: 9 people, 13.24%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 7.35%
Bipolar Disorder (mood disorder): 3 people, 4.41%
Cardiac Failure Congestive: 3 people, 4.41%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 3 people, 4.41%
Hepatitis C: 3 people, 4.41%
Neuropathy Peripheral (surface nerve damage): 2 people, 2.94%
Allergic Rhinitis: 2 people, 2.94%
Constipation: 2 people, 2.94%

* Approximation only. Some reports may have incomplete information.

Do you take Lisinopril and have Drug level above therapeutic?

Check whether Drug level above therapeutic is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Dobrosavljevi? Vukojevi? D, Stojkovi? Filipovi? J, Sjerobabin M, Vukovi? J, Vesi? S, "Lisinopril-induced pemphigus foliaceus in a patient with diabetes mellitus and Kaposi-Juliusberg varicelliform eruption", Serbian Journal of Dermatology and Venerology, 2012 Dec .

Related studies

Lisinopril side effects by duration, gender and age:

Lisinopril side effects (345,933 reports)

Drug level above therapeutic treatments and more:

Drug level above therapeutic (5,397 reports)

Common drugs associated with Drug level above therapeutic:

All the drugs that are associated with Drug level above therapeutic:

Drug level above therapeutic (759 drugs)

Common conditions associated with Drug level above therapeutic:

Pain: 146 reports

All the conditions that are associated with Drug level above therapeutic:

Drug level above therapeutic (387 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lisinopril (the active ingredients of Lisinopril) and Lisinopril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.