Loraz and Female genital tract fistula - a phase IV clinical study of FDA data

Summary:

We study 153,224 people who have side effects when taking Loraz. Female genital tract fistula is found, especially among people who are 60+ old, have been taking the drug for < 1 month, also take Vitamin d and have Crohn's disease.

The phase IV clinical study analyzes which people take Loraz and have Female genital tract fistula. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 26, 2023

153,224 people reported to have side effects when taking Loraz.
Among them, 25 people (0.02%) have Female genital tract fistula.

What is Loraz?

Loraz has active ingredients of lorazepam. It is used in stress and anxiety. Currently, eHealthMe is studying from 157,157 Loraz users.

What is Female genital tract fistula?

Female genital tract fistula (passage in genital tract of female) is found to be associated with 566 drugs and 318 conditions by eHealthMe. Currently, we are studying 1,941 people who have Female genital tract fistula.

Number of Loraz and Female genital tract fistula reports submitted per year:

Could Loraz cause Female genital tract fistula?

Time on Loraz when people have Female genital tract fistula *:

Age of people who have Female genital tract fistula when taking Loraz *:

Common drugs people take besides Loraz *:

Common side effects people have besides Female genital tract fistula *:

Crohn's Disease (condition that causes inflammation of the gastrointestinal tract): 7 people, 28.00%
Intestinal Obstruction: 6 people, 24.00%
Infection: 4 people, 16.00%
Peripheral Swelling: 4 people, 16.00%
Heart Rate Increased: 4 people, 16.00%
Cellulitis (infection under the skin): 4 people, 16.00%
Chills (felling of cold): 4 people, 16.00%
Post Procedural Complication: 4 people, 16.00%
Dehydration (dryness resulting from the removal of water): 4 people, 16.00%
Impaired Healing: 4 people, 16.00%

Common conditions people have *:

Crohn's Disease (condition that causes inflammation of the gastrointestinal tract): 10 people, 40.00%
Pain: 7 people, 28.00%
Nausea (feeling of having an urge to vomit): 4 people, 16.00%
High Blood Pressure: 3 people, 12.00%
High Blood Cholesterol: 3 people, 12.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 12.00%
Delusion (a false belief or opinion): 3 people, 12.00%
Nausea And Vomiting: 3 people, 12.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 12.00%
Electrolyte Imbalance: 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

Do you take Loraz and have Female genital tract fistula?

Check whether Female genital tract fistula is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Loraz side effects by duration, gender and age:

Loraz side effects (157,157 reports)

Female genital tract fistula treatments and more:

Female genital tract fistula (1,941 reports)

Common drugs associated with Female genital tract fistula:

How the study uses the data?

The study uses data from the FDA. It is based on lorazepam (the active ingredients of Loraz) and Loraz (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.