Losartan and Thrombotic stroke - a phase IV clinical study of FDA data

Summary:

Thrombotic stroke is found among people who take Losartan, especially for people who are male, 60+ old.

The phase IV clinical study analyzes which people take Losartan and have Thrombotic stroke. It is created by eHealthMe based on reports of 140,693 people who have side effects when taking Losartan from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Mar, 17, 2023

140,693 people reported to have side effects when taking Losartan.
Among them, 12 people (0.01%) have Thrombotic stroke.

What is Losartan?

Losartan has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 146,744 Losartan users for its effectiveness, alternative drugs and more.

What is Thrombotic stroke?

Thrombotic stroke (stroke due to clot formation) is found to be associated with 523 drugs and 280 conditions by eHealthMe.

Number of Losartan and Thrombotic stroke reports submitted per year:

Gender of people who have Thrombotic stroke when taking Losartan *:

female: 33.33 %
male: 66.67 %

Age of people who have Thrombotic stroke when taking Losartan *:

Common drugs people take besides Losartan *:

Common side effects people have besides Thrombotic stroke *:

Haemorrhagic Stroke (stroke caused by the rupture of a blood vessel in the brain): 3 people, 25.00%
Memory Loss: 3 people, 25.00%
Speech Impairment (Adult) (inability to speak (adult)): 2 people, 16.67%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 16.67%
Fever: 2 people, 16.67%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 16.67%
White Blood Cell Count Decreased: 1 person, 8.33%
Cerebral Haemorrhage (bleeding within the brain): 1 person, 8.33%
Consciousness - Decreased: 1 person, 8.33%
Death: 1 person, 8.33%

Common conditions people have *:

Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 2 people, 16.67%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 16.67%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 16.67%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 16.67%
Gout (uric acid crystals building up in the body): 1 person, 8.33%
Arrhythmias (irregular heartbeat): 1 person, 8.33%
Chronic Kidney Disease: 1 person, 8.33%
Diabetes: 1 person, 8.33%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 1 person, 8.33%
Fluid Retention (an abnormal accumulation of fluid in the blood): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Losartan and have Thrombotic stroke?

Check whether Thrombotic stroke is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Lai SW, Lin HF, Lin CL, Liao KF, "No association between losartan use and acute pancreatitis in hypertensive patients", Eur J Hosp Pharm, 2017 Mar .

Related studies

How severe was Thrombotic stroke and when was it recovered:

Thrombotic stroke in Losartan

Expand to all the drugs that have ingredients of losartan potassium:

Thrombotic stroke and drugs with ingredients of losartan potassium (18 reports)

Alternative drugs to, pros and cons of Losartan:

Losartan (146,744 reports)

Common Losartan side effects:

Fatigue (feeling of tiredness): 10,299 reports
Diarrhea: 8,336 reports
High blood pressure: 8,037 reports
Drug ineffective: 7,816 reports
Breathing difficulty: 7,473 reports
Dizziness: 7,393 reports

Browse all side effects of Losartan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Thrombotic stroke treatments and more:

Thrombotic stroke (1,012 reports)

COVID vaccines that are related to Thrombotic stroke:

All the drugs that are associated with Thrombotic stroke:

Thrombotic stroke (523 drugs)

All the conditions that are associated with Thrombotic stroke:

Thrombotic stroke (280 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on losartan potassium (the active ingredients of Losartan) and Losartan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.