Lotemax and Knee joint replacement - a phase IV clinical study of FDA data


Knee joint replacement is found among people who take Lotemax, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months.

The phase IV clinical study analyzes which people take Lotemax and have Knee joint replacement. It is created by eHealthMe based on reports of 3,801 people who have side effects when taking Lotemax from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Dec, 07, 2022

3,801 people reported to have side effects when taking Lotemax.
Among them, 6 people (0.16%) have Knee joint replacement.

What is Lotemax?

Lotemax has active ingredients of loteprednol etabonate. It is often used in uveitis. eHealthMe is studying from 3,869 Lotemax users for its effectiveness, alternative drugs and more.

What is Knee joint replacement?

Knee joint replacement is found to be associated with 1,745 drugs and 1,077 conditions by eHealthMe.

Number of Lotemax and Knee joint replacement reports submitted per year:

Could Lotemax cause Knee joint replacement?

Time on Lotemax when people have Knee joint replacement *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 50 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Knee joint replacement when taking Lotemax *:

  • female: 66.67 %
  • male: 33.33 %

Age of people who have Knee joint replacement when taking Lotemax *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 25 %
  • 60+: 75 %

Common drugs people take besides Lotemax *:

  1. Advair Diskus 100/50: 2 people, 33.33%
  2. Enbrel: 2 people, 33.33%
  3. Forteo: 2 people, 33.33%
  4. Diclofenac: 2 people, 33.33%
  5. Hydrocodone: 2 people, 33.33%
  6. Demerol: 2 people, 33.33%
  7. Imitrex: 2 people, 33.33%
  8. Klonopin: 2 people, 33.33%
  9. Lovenox: 2 people, 33.33%
  10. Cymbalta: 2 people, 33.33%

Common side effects people have besides Knee joint replacement *:

  1. Fatigue (feeling of tiredness): 3 people, 50.00%
  2. Vitreous Injury (eye injury): 2 people, 33.33%
  3. Head Injury: 2 people, 33.33%
  4. Gait Disturbance: 2 people, 33.33%
  5. Flatulence (flatus expelled through the anus): 2 people, 33.33%
  6. Fever: 2 people, 33.33%
  7. Fear: 2 people, 33.33%
  8. Eye Pain: 2 people, 33.33%
  9. Dysstasia (difficulty in standing): 2 people, 33.33%
  10. Drug Ineffective: 2 people, 33.33%

Common conditions people have *:

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 33.33%
  2. Osteoporosis (bones weak and more likely to break): 2 people, 33.33%
  3. Oral Herpes (viral infection of mouth): 2 people, 33.33%
  4. Diarrhea: 2 people, 33.33%
  5. Sleep Disorder: 1 person, 16.67%
  6. Pain: 1 person, 16.67%
  7. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 16.67%
  8. Insomnia (sleeplessness): 1 person, 16.67%
  9. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 16.67%
  10. Anaemia (lack of blood): 1 person, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Lotemax and have Knee joint replacement?

Check whether Knee joint replacement is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Knee joint replacement and when was it recovered:

Expand to all the drugs that have ingredients of loteprednol etabonate:

Alternative drugs to, pros and cons of Lotemax:

Common Lotemax side effects:

Browse all side effects of Lotemax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Knee joint replacement treatments and more:

COVID vaccines that are related to Knee joint replacement:

Common drugs associated with Knee joint replacement:

All the drugs that are associated with Knee joint replacement:

Common conditions associated with Knee joint replacement:

All the conditions that are associated with Knee joint replacement:

How the study uses the data?

The study uses data from the FDA. It is based on loteprednol etabonate (the active ingredients of Lotemax) and Lotemax (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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