Lupron and Skin cancer - a phase IV clinical study of FDA data


Skin cancer is found among people who take Lupron, especially for people who are male, 60+ old.

The phase IV clinical study analyzes which people take Lupron and have Skin cancer. It is created by eHealthMe based on reports of 37,338 people who have side effects when taking Lupron from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Jan, 30, 2023

37,338 people reported to have side effects when taking Lupron.
Among them, 54 people (0.14%) have Skin cancer.

What is Lupron?

Lupron has active ingredients of leuprolide acetate. It is often used in endometriosis. eHealthMe is studying from 37,941 Lupron users for its effectiveness, alternative drugs and more.

What is Skin cancer?

Skin cancer is found to be associated with 1,361 drugs and 741 conditions by eHealthMe.

Number of Lupron and Skin cancer reports submitted per year:

Could Lupron cause Skin cancer?

Gender of people who have Skin cancer when taking Lupron *:

  • female: 3.7 %
  • male: 96.3 %

Age of people who have Skin cancer when taking Lupron *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 7.89 %
  • 60+: 92.11 %

Common drugs people take besides Lupron *:

  1. Zometa: 28 people, 51.85%
  2. Peridex: 23 people, 42.59%
  3. Percocet: 20 people, 37.04%
  4. Casodex: 19 people, 35.19%
  5. Gabapentin: 15 people, 27.78%
  6. Aspirin: 14 people, 25.93%
  7. Elavil: 13 people, 24.07%
  8. Benicar: 13 people, 24.07%
  9. Ms Contin: 13 people, 24.07%
  10. Lidoderm: 13 people, 24.07%

Common side effects people have besides Skin cancer *:

  1. Oedema Peripheral (superficial swelling): 28 people, 51.85%
  2. Stress And Anxiety: 28 people, 51.85%
  3. Breathing Difficulty: 27 people, 50.00%
  4. Pain: 27 people, 50.00%
  5. Osteonecrosis Of Jaw (death of bone of jaw): 27 people, 50.00%
  6. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 27 people, 50.00%
  7. Back Pain: 26 people, 48.15%
  8. Fatigue (feeling of tiredness): 24 people, 44.44%
  9. Pain In Jaw: 21 people, 38.89%
  10. Intervertebral Disc Protrusion (spinal disc protrusion): 21 people, 38.89%

Common conditions people have *:

  1. Metastases To Bone (cancer spreads to bone): 14 people, 25.93%
  2. Pain: 4 people, 7.41%
  3. Osteoporosis (bones weak and more likely to break): 4 people, 7.41%
  4. Hot Flush (sudden feelings of heat): 3 people, 5.56%
  5. Primary Myelofibrosis (primary disorder of the bone marrow): 3 people, 5.56%
  6. Gout (uric acid crystals building up in the body): 3 people, 5.56%
  7. Tumor: 2 people, 3.70%
  8. Cardiac Infection (an infection of the heart): 1 person, 1.85%
  9. Crohn's Disease (condition that causes inflammation of the gastrointestinal tract): 1 person, 1.85%
  10. Fungal Infection: 1 person, 1.85%

* Approximation only. Some reports may have incomplete information.

Do you take Lupron and have Skin cancer?

Check whether Skin cancer is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

How severe was Skin cancer and when was it recovered:

Expand to all the drugs that have ingredients of leuprolide acetate:

Alternative drugs to, pros and cons of Lupron:

Common Lupron side effects:

Browse all side effects of Lupron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Skin cancer treatments and more:

COVID vaccines that are related to Skin cancer:

Common drugs associated with Skin cancer:

All the drugs that are associated with Skin cancer:

Common conditions associated with Skin cancer:

All the conditions that are associated with Skin cancer:

How the study uses the data?

The study uses data from the FDA. It is based on leuprolide acetate (the active ingredients of Lupron) and Lupron (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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