Lyrica and Insomnia - a phase IV clinical study of FDA data

Summary:

Insomnia is found among people who take Lyrica, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Lyrica and have Insomnia. It is created by eHealthMe based on reports of 243,378 people who have side effects when taking Lyrica from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Dec, 14, 2022

243,378 people reported to have side effects when taking Lyrica.
Among them, 10,535 people (4.33%) have Insomnia.

What is Lyrica?

Lyrica has active ingredients of pregabalin. It is often used in fibromyalgia. eHealthMe is studying from 249,011 Lyrica users for its effectiveness, alternative drugs and more.

What is Insomnia?

Insomnia (sleeplessness) is found to be associated with 4,629 drugs and 4,943 conditions by eHealthMe.

Number of Lyrica and Insomnia reports submitted per year:

* Approximation only. Some reports may have incomplete information.

Do you take Lyrica and have Insomnia?

Check whether Insomnia is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
Bonnet U, Taazimi B, Grabbe HD, "Pregabalin-Related Hypertriglyceridemia", Psychosomatics, 2014 Nov .

Related studies

How severe was Insomnia and when was it recovered:

Insomnia in Lyrica

Expand to all the drugs that have ingredients of pregabalin:

Insomnia and drugs with ingredients of pregabalin (11,733 reports)

Alternative drugs to, pros and cons of Lyrica:

Lyrica (249,011 reports)

Common Lyrica side effects:

Pain: 30,908 reports
Drug ineffective: 25,036 reports
Dizziness: 14,707 reports
Malaise (a feeling of general discomfort or uneasiness): 13,952 reports
Fatigue (feeling of tiredness): 13,177 reports
Weight increased: 12,245 reports

Browse all side effects of Lyrica:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Insomnia treatments and more:

Insomnia (388,133 reports)

COVID vaccines that are related to Insomnia:

Common drugs associated with Insomnia:

All the drugs that are associated with Insomnia:

Insomnia (4,629 drugs)

Common conditions associated with Insomnia:

All the conditions that are associated with Insomnia:

Insomnia (4,943 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pregabalin (the active ingredients of Lyrica) and Lyrica (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.