Macrobid and Neuralgia - a phase IV clinical study of FDA data


Neuralgia is found among people who take Macrobid, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Macrobid and have Neuralgia. It is created by eHealthMe based on reports of 7,497 people who have side effects when taking Macrobid from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Dec, 07, 2022

7,497 people reported to have side effects when taking Macrobid.
Among them, 29 people (0.39%) have Neuralgia.

What is Macrobid?

Macrobid has active ingredients of nitrofurantoin; nitrofurantoin, macrocrystalline. It is often used in urinary tract infection. eHealthMe is studying from 8,326 Macrobid users for its effectiveness, alternative drugs and more.

What is Neuralgia?

Neuralgia (pain in one or more nerves) is found to be associated with 2,187 drugs and 1,650 conditions by eHealthMe.

Number of Macrobid and Neuralgia reports submitted per year:

Could Macrobid cause Neuralgia?

Time on Macrobid when people have Neuralgia *:

  • < 1 month: 66.67 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 33.33 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Neuralgia when taking Macrobid *:

  • female: 89.29 %
  • male: 10.71 %

Age of people who have Neuralgia when taking Macrobid *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 4 %
  • 20-29: 4 %
  • 30-39: 32 %
  • 40-49: 4 %
  • 50-59: 8 %
  • 60+: 48 %

Common drugs people take besides Macrobid *:

  1. Ativan: 10 people, 34.48%
  2. Ambien: 8 people, 27.59%
  3. Lorazepam: 7 people, 24.14%
  4. Lyrica: 6 people, 20.69%
  5. Tylenol: 6 people, 20.69%
  6. Lipitor: 6 people, 20.69%
  7. Norco: 6 people, 20.69%
  8. Valtrex: 6 people, 20.69%
  9. Tagamet: 6 people, 20.69%
  10. Prilosec: 6 people, 20.69%

Common side effects people have besides Neuralgia *:

  1. Pain: 14 people, 48.28%
  2. Weakness: 13 people, 44.83%
  3. Insomnia (sleeplessness): 13 people, 44.83%
  4. Back Pain: 12 people, 41.38%
  5. Pain In Extremity: 11 people, 37.93%
  6. Heart Palpitations (feelings or sensations that your heart is pounding or racing): 11 people, 37.93%
  7. Dizziness: 11 people, 37.93%
  8. Nausea (feeling of having an urge to vomit): 11 people, 37.93%
  9. Fatigue (feeling of tiredness): 10 people, 34.48%
  10. Fever: 9 people, 31.03%

Common conditions people have *:

  1. Pain: 8 people, 27.59%
  2. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 17.24%
  3. Oral Herpes (viral infection of mouth): 3 people, 10.34%
  4. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 10.34%
  5. Fever: 3 people, 10.34%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 6.90%
  7. Ovarian Cancer (cancer of ovary): 2 people, 6.90%
  8. Cardiac Failure Congestive: 1 person, 3.45%
  9. High Blood Cholesterol: 1 person, 3.45%
  10. Heart Attack: 1 person, 3.45%

* Approximation only. Some reports may have incomplete information.

Do you take Macrobid and have Neuralgia?

Check whether Neuralgia is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Neuralgia and when was it recovered:

Expand to all the drugs that have ingredients of nitrofurantoin; nitrofurantoin, macrocrystalline:

Alternative drugs to, pros and cons of Macrobid:

Common Macrobid side effects:

Browse all side effects of Macrobid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Neuralgia treatments and more:

COVID vaccines that are related to Neuralgia:

Common drugs associated with Neuralgia:

All the drugs that are associated with Neuralgia:

Common conditions associated with Neuralgia:

All the conditions that are associated with Neuralgia:

How the study uses the data?

The study uses data from the FDA. It is based on nitrofurantoin; nitrofurantoin, macrocrystalline (the active ingredients of Macrobid) and Macrobid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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