Maxzide and Rib fracture - a phase IV clinical study of FDA data


Rib fracture is found among people who take Maxzide, especially for people who are female, 60+ old.

The phase IV clinical study analyzes which people take Maxzide and have Rib fracture. It is created by eHealthMe based on reports of 8,629 people who have side effects when taking Maxzide from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 22, 2022

8,629 people reported to have side effects when taking Maxzide.
Among them, 48 people (0.56%) have Rib fracture.

What is Maxzide?

Maxzide has active ingredients of hydrochlorothiazide; triamterene. It is often used in high blood pressure. eHealthMe is studying from 8,914 Maxzide users for its effectiveness, alternative drugs and more.

What is Rib fracture?

Rib fracture is found to be associated with 1,871 drugs and 1,153 conditions by eHealthMe.

Number of Maxzide and Rib fracture reports submitted per year:

Could Maxzide cause Rib fracture?

Gender of people who have Rib fracture when taking Maxzide *:

  • female: 91.49 %
  • male: 8.51 %

Age of people who have Rib fracture when taking Maxzide *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 16.13 %
  • 50-59: 12.9 %
  • 60+: 70.97 %

Common drugs people take besides Maxzide *:

  1. Lasix: 26 people, 54.17%
  2. Prevacid: 24 people, 50.00%
  3. Prednisone: 23 people, 47.92%
  4. Prilosec: 19 people, 39.58%
  5. Arimidex: 18 people, 37.50%
  6. Effexor: 18 people, 37.50%
  7. Zometa: 17 people, 35.42%
  8. Cytoxan: 17 people, 35.42%
  9. Morphine: 17 people, 35.42%
  10. Proventil: 17 people, 35.42%

Common side effects people have besides Rib fracture *:

  1. Fall: 34 people, 70.83%
  2. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 24 people, 50.00%
  3. Pain: 22 people, 45.83%
  4. Arthritis (form of joint disorder that involves inflammation of one or more joints): 20 people, 41.67%
  5. Chest Pain: 20 people, 41.67%
  6. Gait Disturbance: 19 people, 39.58%
  7. Injury: 19 people, 39.58%
  8. Stress And Anxiety: 19 people, 39.58%
  9. Road Traffic Accident: 18 people, 37.50%
  10. Kyphosis (a condition of over-curvature of the thoracic vertebrae (upper back)): 18 people, 37.50%

Common conditions people have *:

  1. Muscle Spasms (muscle contraction): 16 people, 33.33%
  2. Breast Cancer: 16 people, 33.33%
  3. Breast Cancer Metastatic: 16 people, 33.33%
  4. Metastases To Bone (cancer spreads to bone): 16 people, 33.33%
  5. Constipation: 16 people, 33.33%
  6. Osteoporosis (bones weak and more likely to break): 8 people, 16.67%
  7. Hypersensitivity: 3 people, 6.25%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 4.17%
  9. Psoriasis (immune-mediated disease that affects the skin): 2 people, 4.17%
  10. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 2.08%

* Approximation only. Some reports may have incomplete information.

Do you take Maxzide and have Rib fracture?

Check whether Rib fracture is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Rib fracture and when was it recovered:

Expand to all the drugs that have ingredients of hydrochlorothiazide; triamterene:

Alternative drugs to, pros and cons of Maxzide:

Common Maxzide side effects:

Browse all side effects of Maxzide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Rib fracture treatments and more:

COVID vaccines that are related to Rib fracture:

Common drugs associated with Rib fracture:

All the drugs that are associated with Rib fracture:

Common conditions associated with Rib fracture:

All the conditions that are associated with Rib fracture:

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide; triamterene (the active ingredients of Maxzide) and Maxzide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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