Mayzent and Decreased muscle tone - a phase IV clinical study of FDA data


Decreased muscle tone is reported only by a few people who take Mayzent.

The phase IV clinical study analyzes which people take Mayzent and have Decreased muscle tone. It is created by eHealthMe based on reports of 7,239 people who have side effects while taking Mayzent from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 14, 2022

7,239 people reported to have side effects when taking Mayzent.
Among them, 4 people (0.06%) have Decreased muscle tone.

What is Mayzent?

Mayzent has active ingredients of siponimod fumaric acid. eHealthMe is studying from 7,240 Mayzent users for its effectiveness, alternative drugs and more.

What is Decreased muscle tone?

Decreased muscle tone is found to be associated with 2,102 drugs and 1,629 conditions by eHealthMe.

Number of Mayzent and Decreased muscle tone reports submitted per year:

Could Mayzent cause Decreased muscle tone?

Time on Mayzent when people have Decreased muscle tone *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Decreased muscle tone when taking Mayzent *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Decreased muscle tone when taking Mayzent *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

Common drugs people take besides Mayzent *:

  1. Zinbryta: 3 people, 75.00%
  2. Valacyclovir: 3 people, 75.00%
  3. Tylenol: 3 people, 75.00%
  4. Synthroid: 3 people, 75.00%
  5. Percocet: 3 people, 75.00%
  6. Benadryl: 3 people, 75.00%
  7. Medrol: 2 people, 50.00%
  8. Ampyra: 2 people, 50.00%
  9. Tysabri: 1 person, 25.00%
  10. Solu-Medrol: 1 person, 25.00%

Common side effects people have besides Decreased muscle tone *:

  1. Lymphocyte Count Decreased: 4 people, 100.00%
  2. Pain: 4 people, 100.00%
  3. Weakness: 4 people, 100.00%
  4. Cough: 4 people, 100.00%
  5. Fall: 4 people, 100.00%
  6. Hypoaesthesia (reduced sense of touch or sensation): 3 people, 75.00%
  7. Hoarseness Or Changing Voice: 3 people, 75.00%
  8. Hemiplegia (paralysis of one side of the body): 3 people, 75.00%
  9. Hemiparesis (weakness on one side of the body): 3 people, 75.00%
  10. Head Injury: 3 people, 75.00%

Common conditions people have *:

  1. Secondary Progressive Multiple Sclerosis (a stage of ms which comes after relapsing remitting ms in many cases): 2 people, 50.00%
  2. Progressive Relapsing Multiple Sclerosis (chronic autoimmune disease of the central nervous system in which gradual destruction of myelin occurs in patches throughout the brain or spinal cord or both): 2 people, 50.00%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 50.00%
  4. Hyperthyroidism (over activity of the thyroid gland): 2 people, 50.00%
  5. High Blood Pressure: 2 people, 50.00%

* Approximation only. Some reports may have incomplete information.

Do you take Mayzent and have Decreased muscle tone?

Check whether Decreased muscle tone is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Decreased muscle tone and when was it recovered:

Expand to all the drugs that have ingredients of siponimod fumaric acid:

Alternative drugs to, pros and cons of Mayzent:

Common Mayzent side effects:

Browse all side effects of Mayzent:

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Decreased muscle tone treatments and more:

COVID vaccines that are related to Decreased muscle tone:

Common drugs associated with Decreased muscle tone:

All the drugs that are associated with Decreased muscle tone:

Common conditions associated with Decreased muscle tone:

All the conditions that are associated with Decreased muscle tone:

How the study uses the data?

The study uses data from the FDA. It is based on siponimod fumaric acid (the active ingredients of Mayzent) and Mayzent (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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