Mefenamic acid and Gastric ulcer - a phase IV clinical study of FDA data


Gastric ulcer is found among people who take Mefenamic acid, especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years.

The phase IV clinical study analyzes which people take Mefenamic acid and have Gastric ulcer. It is created by eHealthMe based on reports of 4,056 people who have side effects when taking Mefenamic acid from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Jun, 04, 2022

4,056 people reported to have side effects when taking Mefenamic acid.
Among them, 59 people (1.45%) have Gastric ulcer.

What is Mefenamic acid?

Mefenamic acid has active ingredients of mefenamic acid. It is often used in painful menstrual periods. eHealthMe is studying from 4,135 Mefenamic acid users for its effectiveness, alternative drugs and more.

What is Gastric ulcer?

Gastric ulcer (stomach ulcer) is found to be associated with 3,264 drugs and 3,084 conditions by eHealthMe.

Number of Mefenamic acid and Gastric ulcer reports submitted per year:

Could Mefenamic acid cause Gastric ulcer?

Time on Mefenamic acid when people have Gastric ulcer *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 36.36 %
  • 6 - 12 months: 9.09 %
  • 1 - 2 years: 54.55 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Gastric ulcer when taking Mefenamic acid *:

  • female: 56.36 %
  • male: 43.64 %

Age of people who have Gastric ulcer when taking Mefenamic acid *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 11.36 %
  • 30-39: 4.55 %
  • 40-49: 34.09 %
  • 50-59: 9.09 %
  • 60+: 40.91 %

Common drugs people take besides Mefenamic acid *:

  1. Omeprazole: 12 people, 20.34%
  2. Diclofenac Sodium: 11 people, 18.64%
  3. Acetylsalicylic Acid: 11 people, 18.64%
  4. Paracetamol: 11 people, 18.64%
  5. Diclofenac: 10 people, 16.95%
  6. Kaletra: 9 people, 15.25%
  7. Norvir: 9 people, 15.25%
  8. Triazolam: 9 people, 15.25%
  9. Ribavirin: 8 people, 13.56%
  10. Lorazepam: 7 people, 11.86%

Common side effects people have besides Gastric ulcer *:

  1. Anaemia (lack of blood): 12 people, 20.34%
  2. Haematemesis (vomiting of blood): 9 people, 15.25%
  3. Hyperlactacidaemia (the acidosis and also reduces the capacity of the kidney): 9 people, 15.25%
  4. Fever: 9 people, 15.25%
  5. Pancreatitis Acute (sudden inflammation of pancreas): 9 people, 15.25%
  6. Disseminated Intravascular Coagulation (systemic activation of blood coagulation): 9 people, 15.25%
  7. Abdominal Pain: 9 people, 15.25%
  8. Aphthous Stomatitis (mouth ulcer): 7 people, 11.86%
  9. Behcet's Syndrome (involves inflammation of the blood vessels): 7 people, 11.86%
  10. Melaena (the passage of black, tarry stools): 7 people, 11.86%

Common conditions people have *:

  1. Hiv Infection: 12 people, 20.34%
  2. Migraine (headache): 11 people, 18.64%
  3. High Blood Pressure: 9 people, 15.25%
  4. Hepatitis C: 7 people, 11.86%
  5. Nausea And Vomiting: 7 people, 11.86%
  6. Insomnia (sleeplessness): 7 people, 11.86%
  7. Headache (pain in head): 6 people, 10.17%
  8. Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 5 people, 8.47%
  9. Oral Candidiasis (fungal infection of mouth): 5 people, 8.47%
  10. Heavy Or Prolong Menstrual Bleeding: 4 people, 6.78%

* Approximation only. Some reports may have incomplete information.

Do you take Mefenamic acid and have Gastric ulcer?

Check whether Gastric ulcer is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

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Common Mefenamic acid side effects:

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Common drugs associated with Gastric ulcer:

All the drugs that are associated with Gastric ulcer:

Common conditions associated with Gastric ulcer:

All the conditions that are associated with Gastric ulcer:

How the study uses the data?

The study uses data from the FDA. It is based on mefenamic acid (the active ingredients of Mefenamic acid) and Mefenamic acid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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