Melphalan hydrochloride and Waldenstrom's macroglobulinaemia - a phase IV clinical study of FDA data
Summary:
Waldenstrom's macroglobulinaemia is reported only by a few people who take Melphalan Hydrochloride.
The phase IV clinical study analyzes which people take Melphalan hydrochloride and have Waldenstrom's macroglobulinaemia. It is created by eHealthMe based on reports of 3,866 people who have side effects while taking Melphalan hydrochloride from the FDA, and is updated regularly.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
3,866 people reported to have side effects when taking Melphalan hydrochloride.
Among them, 3 people (0.08%) have Waldenstrom's macroglobulinaemia.
What is Melphalan hydrochloride?
Melphalan hydrochloride has active ingredients of melphalan hydrochloride. eHealthMe is studying from 3,872 Melphalan hydrochloride users for its effectiveness, alternative drugs and more.
What is Waldenstrom's macroglobulinaemia?
Waldenstrom's macroglobulinaemia (cancer affects small lymphocytes (white blood cells)) is found to be associated with 471 drugs and 284 conditions by eHealthMe.
Number of Melphalan hydrochloride and Waldenstrom's macroglobulinaemia reports submitted per year:

Gender of people who have Waldenstrom's macroglobulinaemia when taking Melphalan hydrochloride *:
- female: 0.0 %
- male: 100 %
Age of people who have Waldenstrom's macroglobulinaemia when taking Melphalan hydrochloride *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 100 %
- 60+: 0.0 %
Common drugs people take besides Melphalan hydrochloride *:
- Zosyn: 3 people, 100.00%
- Zometa: 3 people, 100.00%
- Ambien: 3 people, 100.00%
- Amoxicillin: 3 people, 100.00%
- Aredia: 3 people, 100.00%
- Aspirin: 3 people, 100.00%
- Ceftriaxone: 3 people, 100.00%
- Clonidine: 3 people, 100.00%
- Colace: 3 people, 100.00%
- Diovan: 3 people, 100.00%
Common side effects people have besides Waldenstrom's macroglobulinaemia *:
- Weakness: 3 people, 100.00%
- Viith Nerve Paralysis: 3 people, 100.00%
- Left Ventricular Hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart): 3 people, 100.00%
- Joint Swelling: 3 people, 100.00%
- Joint Range Of Motion Decreased (disease of joint movement): 3 people, 100.00%
- Joint Pain: 3 people, 100.00%
- Intervertebral Disc Space Narrowing (spinal disc space narrowing): 3 people, 100.00%
- Intervertebral Disc Degeneration (spinal disc degeneration): 3 people, 100.00%
- Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 3 people, 100.00%
- Hyperviscosity Syndrome (condition in which blood is not able to flow freely through your arteries): 3 people, 100.00%
Common conditions people have *:
- Multiple Myeloma (cancer of the plasma cells): 3 people, 100.00%
- High Blood Pressure: 3 people, 100.00%
* Approximation only. Some reports may have incomplete information.
Do you take Melphalan hydrochloride and have Waldenstrom's macroglobulinaemia?
Check whether Waldenstrom's macroglobulinaemia is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Waldenstrom's macroglobulinaemia and when was it recovered:
Expand to all the drugs that have ingredients of melphalan hydrochloride:
Alternative drugs to, pros and cons of Melphalan hydrochloride:
- Melphalan hydrochloride (3,872 reports)
Common Melphalan hydrochloride side effects:
- Abdominal pain: 160 reports
- Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant): 147 reports
- Acute graft versus host disease in skin (acute complication on skin following an allogeneic tissue/blood transplant): 105 reports
- Acute kidney failure: 153 reports
- Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 109 reports
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 217 reports
- Anaemia (lack of blood): 370 reports
- Anhedonia (inability to experience pleasure from activities usually found enjoyable): 192 reports
- Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 151 reports
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 109 reports
- Aseptic necrosis (the death of bone tissue due to a lack of blood supply): 145 reports
- Atelectasis (partial or complete collapse of the lung): 181 reports
- Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 117 reports
- Back pain: 222 reports
- Bone disorder: 273 reports
- Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries): 148 reports
- Bone pain: 107 reports
- Breathing difficulty: 245 reports
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 116 reports
- Cardiac failure congestive: 140 reports
- Cataract (clouding of the lens inside the eye): 107 reports
- Cellulitis (infection under the skin): 140 reports
- Chest pain: 188 reports
- Confusional state: 112 reports
- Constipation: 206 reports
- Cough: 121 reports
- Death: 196 reports
- Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 130 reports
- Depression: 167 reports
- Diarrhea: 290 reports
- Dizziness: 143 reports
- Emotional distress: 121 reports
- Enlarged heart: 110 reports
- Fall: 150 reports
- Fatigue (feeling of tiredness): 242 reports
- Febrile neutropenia (fever with reduced white blood cells): 206 reports
- Fever: 369 reports
- Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 157 reports
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract): 134 reports
- General physical health deterioration (weak health status): 167 reports
- Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 101 reports
- Headache (pain in head): 115 reports
- Herpes zoster: 136 reports
- High blood pressure: 207 reports
- Hypoaesthesia (reduced sense of touch or sensation): 140 reports
- Hypotension (abnormally low blood pressure): 123 reports
- Infection: 228 reports
- Injury: 210 reports
- Insomnia (sleeplessness): 107 reports
- Intervertebral disc degeneration (spinal disc degeneration): 124 reports
- Joint pain: 164 reports
- Leukopenia (less number of white blood cells in blood): 102 reports
- Mucosal inflammation (infection of mucous membrane): 222 reports
- Multi-organ failure (multisystem organ failure): 108 reports
- Multiple myeloma (cancer of the plasma cells): 227 reports
- Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 119 reports
- Nausea (feeling of having an urge to vomit): 253 reports
- Nausea and vomiting: 184 reports
- Neoplasm malignant (cancer tumour): 101 reports
- Neuropathy peripheral (surface nerve damage): 275 reports
- Oedema peripheral (superficial swelling): 199 reports
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 179 reports
- Osteolysis (dissolution of bone): 103 reports
- Osteomyelitis (infection of bone): 165 reports
- Osteonecrosis of jaw (death of bone of jaw): 348 reports
- Osteopenia (a condition where bone mineral density is lower than normal): 175 reports
- Osteoporosis (bones weak and more likely to break): 160 reports
- Pain: 435 reports
- Pain in jaw: 192 reports
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 254 reports
- Pleural effusion (water on the lungs): 187 reports
- Pneumonia: 358 reports
- Rashes (redness): 202 reports
- Renal failure acute (rapid kidney dysfunction): 101 reports
- Renal failure chronic (long lasting kidney dysfunction): 115 reports
- Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 127 reports
- Rib fracture: 112 reports
- Sepsis (a severe blood infection that can lead to organ failure and death): 222 reports
- Spinal osteoarthritis (joint cartilage loss in spine): 157 reports
- Stem cell transplant: 125 reports
- Stress and anxiety: 367 reports
- Swallowing difficulty: 115 reports
- Swelling: 125 reports
- Thrombocytopenia (decrease of platelets in blood): 339 reports
- Tooth extraction: 156 reports
- Urinary tract infection: 114 reports
- Weakness: 251 reports
- Weight decreased: 176 reports
Browse all side effects of Melphalan hydrochloride:
a b c d e f g h i j k l m n o p q r s t u v w x y zWaldenstrom's macroglobulinaemia treatments and more:
- Waldenstrom's macroglobulinaemia (6,558 reports)
COVID vaccines that are related to Waldenstrom's macroglobulinaemia:
- Waldenstrom's macroglobulinaemia in Moderna COVID Vaccine
- Waldenstrom's macroglobulinaemia in Pfizer BioNTech Covid Vaccine
- Waldenstrom's macroglobulinaemia in Johnson and Johnson Covid Vaccine
All the drugs that are associated with Waldenstrom's macroglobulinaemia:
- Waldenstrom's macroglobulinaemia (471 drugs)
All the conditions that are associated with Waldenstrom's macroglobulinaemia:
- Waldenstrom's macroglobulinaemia (284 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on melphalan hydrochloride (the active ingredients of Melphalan hydrochloride) and Melphalan hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
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DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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