Memantine and Pancytopenia - a phase IV clinical study of FDA data


Pancytopenia is found among people who take Memantine, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Memantine and have Pancytopenia. It is created by eHealthMe based on reports of 6,442 people who have side effects when taking Memantine from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On Jun, 28, 2022

6,442 people reported to have side effects when taking Memantine.
Among them, 9 people (0.14%) have Pancytopenia.

What is Memantine?

Memantine has active ingredients of memantine. It is often used in alzheimer's disease. eHealthMe is studying from 6,530 Memantine users for its effectiveness, alternative drugs and more.

What is Pancytopenia?

Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets) is found to be associated with 2,391 drugs and 2,304 conditions by eHealthMe.

Number of Memantine and Pancytopenia reports submitted per year:

Could Memantine cause Pancytopenia?

Time on Memantine when people have Pancytopenia *:

  • < 1 month: 50 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Pancytopenia when taking Memantine *:

  • female: 55.56 %
  • male: 44.44 %

Age of people who have Pancytopenia when taking Memantine *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 12.5 %
  • 40-49: 0.0 %
  • 50-59: 12.5 %
  • 60+: 75.0 %

Common drugs people take besides Memantine *:

  1. Aricept: 2 people, 22.22%
  2. Pantoprazole: 2 people, 22.22%
  3. Namenda: 2 people, 22.22%
  4. Zolpidem: 1 person, 11.11%
  5. Lantus: 1 person, 11.11%
  6. Amoxicillin And Clavulanate Potassium: 1 person, 11.11%
  7. Augmentin: 1 person, 11.11%
  8. Botox: 1 person, 11.11%
  9. Butalbital And Acetaminophen: 1 person, 11.11%
  10. Cambia: 1 person, 11.11%

Common side effects people have besides Pancytopenia *:

  1. Weakness: 3 people, 33.33%
  2. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 2 people, 22.22%
  3. Fatigue (feeling of tiredness): 2 people, 22.22%
  4. Weight Decreased: 1 person, 11.11%
  5. Drug Eruption (adverse drug reaction of the skin): 1 person, 11.11%
  6. Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 1 person, 11.11%
  7. Gait Disturbance: 1 person, 11.11%
  8. Fall: 1 person, 11.11%
  9. Eschar (dead tissue that falls off (sheds) from healthy skin): 1 person, 11.11%
  10. Erythema Multiforme (a type of hypersensitivity reaction): 1 person, 11.11%

Common conditions people have *:

  1. Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 3 people, 33.33%
  2. Stress And Anxiety: 1 person, 11.11%
  3. Schizoaffective Disorder (a mental disorder characterized by disordered thought): 1 person, 11.11%
  4. Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 1 person, 11.11%
  5. Osteoporosis (bones weak and more likely to break): 1 person, 11.11%
  6. Multiple Myeloma (cancer of the plasma cells): 1 person, 11.11%
  7. Breast Cancer: 1 person, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Memantine and have Pancytopenia?

Check whether Pancytopenia is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

Alternative drugs to, pros and cons of Memantine:

Pancytopenia treatments and more:

COVID vaccines that are related to Pancytopenia:

How severe was Pancytopenia and when was it recovered:

Expand to all the drugs that have ingredients of memantine:

Common drugs associated with Pancytopenia:

All the drugs that are associated with Pancytopenia:

Common conditions associated with Pancytopenia:

All the conditions that are associated with Pancytopenia:

How the study uses the data?

The study uses data from the FDA. It is based on memantine (the active ingredients of Memantine) and Memantine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe: