Mercaptopurine and Cytomegalovirus infection - a phase IV clinical study of FDA data

• Mercaptopurine (17,983 reports)

• Abdominal distension: 156 reports
• Abdominal pain: 692 reports
• Abdominal pain upper: 182 reports
• Acute lymphocytic leukaemia recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent): 140 reports
• Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 196 reports
• Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 578 reports
• Alanine aminotransferase increased: 286 reports
• Anaemia (lack of blood): 486 reports
• Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 127 reports
• Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 196 reports
• Arrhythmias (irregular heartbeat): 209 reports
• Aseptic necrosis (the death of bone tissue due to a lack of blood supply): 194 reports
• Aspartate aminotransferase increased: 205 reports
• Back pain: 259 reports
• Bacterial infection: 407 reports
• Blood bilirubin increased: 166 reports
• Blood pressure fluctuation: 129 reports
• Bone marrow failure: 227 reports
• Breathing difficulty: 399 reports
• Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi): 211 reports
• Cellulitis (infection under the skin): 218 reports
• Chest pain: 237 reports
• Chills (felling of cold): 243 reports
• Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection): 315 reports
• Colitis (inflammation of colon): 239 reports
• Constipation: 235 reports
• Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 125 reports
• Cough: 310 reports
• Crohn's disease (condition that causes inflammation of the gastrointestinal tract): 906 reports
• Cytomegalovirus chorioretinitis (infection of choroid and retina of the eye from virus): 166 reports
• Cytomegalovirus infection: 136 reports
• Cytomegalovirus viraemia (cytomegalo virus in blood stream): 137 reports
• Death: 326 reports
• Dehydration (dryness resulting from the removal of water): 223 reports
• Depression: 111 reports
• Diarrhea: 762 reports
• Disease progression: 102 reports
• Dizziness: 293 reports
• Drowsiness: 137 reports
• Drug hypersensitivity: 205 reports
• Drug ineffective: 1,050 reports
• Drug intolerance (drug sensitivity): 130 reports
• Enteritis (inflammation of the small intestine): 152 reports
• Enterobacter infection (infection caused by bacteria of the family enterobacteriaceae): 137 reports
• Fall: 124 reports
• Fatigue (feeling of tiredness): 670 reports
• Febrile bone marrow aplasia (bone marrow greatly decreases or stops production of blood cells): 242 reports
• Febrile neutropenia (fever with reduced white blood cells): 1,401 reports
• Fever: 1,229 reports
• Fungal infection: 230 reports
• Gait disturbance: 118 reports
• Haematochezia (passage of stools containing blood): 134 reports
• Haematotoxicity (toxins that destroy red blood cells): 241 reports
• Haemoglobin decreased: 256 reports
• Haemorrhage (bleeding): 115 reports
• Hair loss: 114 reports
• Headache (pain in head): 626 reports
• Head injury: 114 reports
• Hepatosplenic t-cell lymphoma (neoplasm comprising medium-sized cytotoxic t-cells that show a significant sinusoidal infiltration in the liver, spleen, and bone marrow): 174 reports
• Hepatotoxicity (chemical-driven liver damage): 146 reports
• Herpes zoster: 173 reports
• High blood pressure: 286 reports
• Hyperbilirubinaemia (excess of bilirubin in the blood): 142 reports
• Hyperglycemia (high blood sugar): 116 reports
• Hypersensitivity: 170 reports
• Hypertriglyceridaemia (excess of triglycerides in the blood): 141 reports
• Hypoaesthesia (reduced sense of touch or sensation): 143 reports
• Hypotension (abnormally low blood pressure): 389 reports
• Infection: 220 reports
• Infusion related reaction: 176 reports
• Injection site erythema (redness at injection site): 115 reports
• Injection site pain: 346 reports
• Insomnia (sleeplessness): 108 reports
• Intestinal obstruction: 167 reports
• Itching: 179 reports
• Joint pain: 430 reports
• Leukopenia (less number of white blood cells in blood): 240 reports
• Lymph follicular hypertrophy (an increase in the size of the lymph node follicles): 114 reports
• Malaise (a feeling of general discomfort or uneasiness): 326 reports
• Mucosal inflammation (infection of mucous membrane): 197 reports
• Multi-organ failure (multisystem organ failure): 110 reports
• Muscle aches (muscle pain): 170 reports
• Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 149 reports
• Nasopharyngitis (inflammation of the nasopharynx): 137 reports
• Nausea (feeling of having an urge to vomit): 761 reports
• Nausea and vomiting: 707 reports
• Neuropathy peripheral (surface nerve damage): 180 reports
• Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system): 130 reports
• Neutrophil count decreased (less than normal number of neutrophil a type of blood cell): 177 reports
• Nosebleed (bleeding from nose): 121 reports
• Oedema peripheral (superficial swelling): 101 reports
• Oesophageal candidiasis (fungal infection of oesophagus): 128 reports
• Oral herpes (viral infection of mouth): 115 reports
• Oropharyngeal pain: 174 reports
• Pain: 381 reports
• Pain in extremity: 270 reports
• Pancreatitis (inflammation of pancreas): 334 reports
• Pancreatitis acute (sudden inflammation of pancreas): 133 reports
• Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 465 reports
• Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 156 reports
• Parainfluenzae virus infection: 246 reports
• Pleural effusion (water on the lungs): 138 reports
• Pneumatosis intestinalis (air or gas in an intestine): 129 reports
• Pneumonia: 640 reports
• Pseudomonal sepsis (pseudomonas infections are diseases caused by a bacterium from the genus pseudomonas): 171 reports
• Rashes (redness): 462 reports
• Rectal haemorrhage (bleeding from anus): 162 reports
• Renal impairment (severely reduced kidney function): 103 reports
• Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 171 reports
• Respiratory distress (difficulty in breathing): 128 reports
• Rhinovirus infection: 170 reports
• Seizures (abnormal excessive or synchronous neuronal activity in the brain): 177 reports
• Sepsis (a severe blood infection that can lead to organ failure and death): 487 reports
• Septic shock (shock due to blood infection): 166 reports
• Sinusitis (inflammation of sinus): 167 reports
• Small intestinal obstruction (blockage in small intestine): 115 reports
• Speech impairment (adult) (inability to speak (adult)): 112 reports
• Staphylococcal infection (an infection with staphylococcus bacteria): 122 reports
• Stomatitis (inflammation of mucous membrane of mouth): 165 reports
• Stress and anxiety: 190 reports
• Thrombocytopenia (decrease of platelets in blood): 597 reports
• Ulcerative colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 297 reports
• Upper respiratory tract infection: 160 reports
• Urinary tract infection: 258 reports
• Urticaria (rash of round, red welts on the skin that itch intensely): 107 reports
• Venoocclusive liver disease (small veins in the liver are obstructed): 192 reports
• Venous thrombosis (blood clot (thrombus) that forms within a vein): 110 reports
• Viral infection: 300 reports
• Vision blurred: 102 reports
• Weakness: 471 reports
• Weight decreased: 324 reports
• Weight increased: 234 reports
• White blood cell count decreased: 228 reports

• Cytomegalovirus infection (20,015 reports)

• Acetaminophen: 151 reports
• Acyclovir: 440 reports
• Allopurinol: 363 reports
• Amlodipine: 286 reports
• Amphotericin b: 197 reports
• Aspirin: 311 reports
• Atenolol: 134 reports
• Azathioprine: 809 reports
• Bactrim: 594 reports
• Bendamustine hydrochloride: 164 reports
• Bortezomib: 123 reports
• Budesonide: 144 reports
• Busulfan: 805 reports
• Busulfex: 141 reports
• Campath: 310 reports
• Carboplatin: 123 reports
• Ceftazidime: 106 reports
• Cellcept: 842 reports
• Ciclosporin: 192 reports
• Cisplatin: 173 reports
• Cotrim: 170 reports
• Cyclophosphamide: 2,166 reports
• Cyclosporine: 1,878 reports
• Cytarabine: 492 reports
• Dexamethasone: 323 reports
• Diflucan: 180 reports
• Enbrel: 131 reports
• Epivir: 113 reports
• Etoposide: 492 reports
• Famotidine: 206 reports
• Fluconazole: 576 reports
• Fludara: 1,716 reports
• Fludarabine phosphate: 546 reports
• Folic acid: 104 reports
• Foscavir: 122 reports
• Furosemide: 375 reports
• Ganciclovir: 549 reports
• Ganciclovir sodium: 124 reports
• Heparin: 202 reports
• Humira: 215 reports
• Imuran: 159 reports
• Insulin: 103 reports
• Isoniazid: 117 reports
• Itraconazole: 167 reports
• Lansoprazole: 213 reports
• Lasix: 252 reports
• Levofloxacin: 104 reports
• Lipitor: 111 reports
• Lopurin: 364 reports
• Magnesium: 133 reports
• Medrol: 217 reports
• Melphalan: 300 reports
• Mercaptopurine: 136 reports
• Meropenem: 209 reports
• Methotrexate: 1,484 reports
• Methotrexate sodium: 141 reports
• Methylprednisolone: 737 reports
• Methylprednisolone sodium succinate: 241 reports
• Metronidazole: 139 reports
• Morphine: 147 reports
• Mycophenolate mofetil: 3,461 reports
• Mycophenolic acid: 536 reports
• Myfortic: 271 reports
• Neoral: 760 reports
• Nexium: 135 reports
• Nifedipine: 115 reports
• Norvasc: 187 reports
• Nystatin: 195 reports
• Omeprazole: 465 reports
• Ondansetron: 105 reports
• Pantoprazole: 290 reports
• Paracetamol: 138 reports
• Pentam: 113 reports
• Prednisolone: 2,704 reports
• Prednisone: 2,551 reports
• Prograf: 1,065 reports
• Rabeprazole: 106 reports
• Ranitidine: 175 reports
• Rapamune: 176 reports
• Remicade: 686 reports
• Revlimid: 115 reports
• Rituxan: 193 reports
• Sandimmune: 239 reports
• Simulect: 259 reports
• Sirolimus: 233 reports
• Sodium bicarbonate: 131 reports
• Soliris: 141 reports
• Solu-medrol: 319 reports
• Sulfamethoxazole: 119 reports
• Sulfamethoxazole and trimethoprim: 257 reports
• Tacrolimus: 2,935 reports
• Thiotepa: 453 reports
• Tylenol: 103 reports
• Ursodeoxycholic acid: 118 reports
• Valacyclovir: 137 reports
• Valcyte: 431 reports
• Valganciclovir hydrochloride: 158 reports
• Valtrex: 108 reports
• Velcade: 284 reports
• Vincristine sulfate: 159 reports
• Voriconazole: 153 reports
• Zantac: 102 reports
• Zovirax: 113 reports

All the drugs that are associated with Cytomegalovirus infection:

• Cytomegalovirus infection (1,256 drugs)

• Acute graft versus host disease: 142 reports
• Acute lymphocytic leukemia (all): 224 reports
• Acute myeloid leukaemia: 133 reports
• Acute myeloid leukaemia aggravated: 133 reports
• Aplastic anaemia: 131 reports
• Aplastic anemia: 131 reports
• B-cell lymphoma: 245 reports
• Blood pressure increased: 453 reports
• Bone marrow conditioning regimen: 883 reports
• Burkitt lymphoma: 244 reports
• Cancer - acute childhood leukemia (all): 237 reports
• Cancer chemotherapy: 110 reports
• Chronic lymphocytic leukaemia: 287 reports
• Colitis ulcerative: 588 reports
• Constipation: 124 reports
• Crohn's disease: 384 reports
• Crohns disease: 384 reports
• Cytomegalovirus infection: 303 reports
• Diffuse large b-cell lymphoma: 276 reports
• Disseminated lupus erythematosus: 126 reports
• Gastritis: 106 reports
• Graft rejection: 147 reports
• Graft versus host disease: 298 reports
• Hbp: 453 reports
• Hepatic transplant: 342 reports
• High blood pressure: 453 reports
• Hiv: 286 reports
• Hiv antibody positive: 286 reports
• Hiv infection: 313 reports
• Human immunodeficiency virus infection: 303 reports
• Hypertension: 472 reports
• Ileitis: 384 reports
• Immunodeficiency disorders: 1,008 reports
• Immunosuppression: 1,009 reports
• Inability to sleep: 119 reports
• Infection: 558 reports
• Inflammatory bowel disease - crohn's disease: 403 reports
• Insomnia: 119 reports
• Kidney transplant: 1,398 reports
• Liver transplant: 327 reports
• Lupus erythematosus: 126 reports
• Lymphoma - non-hodgkin's: 276 reports
• Ms: 135 reports
• Multiple myeloma: 478 reports
• Multiple sclerosis: 135 reports
• Non-hodgkin's lymphoma: 293 reports
• Osteoporosis: 139 reports
• Plasma cell myeloma: 422 reports
• Preventive health care: 621 reports
• Regional enteritis: 403 reports
• Renal transplant: 1,398 reports
• Rheumatoid arthritis: 400 reports
• Small non-cleaved cell lymphoma: 261 reports
• Stem cell transplant: 672 reports
• Systemic lupus erythematosus: 126 reports
• Thrombosis: 118 reports
• Transplant - kidney: 1,441 reports
• Transplant - liver: 327 reports
• Ulcerative colitis: 553 reports

All the conditions that are associated with Cytomegalovirus infection:

• Cytomegalovirus infection (990 conditions)

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