Mercaptopurine and Febrile bone marrow aplasia - a phase IV clinical study of FDA data
Summary:
Febrile bone marrow aplasia is found among people who take Mercaptopurine, especially for people who are female, 2-9 old, have been taking the drug for < 1 month.
The phase IV clinical study analyzes which people take Mercaptopurine and have Febrile bone marrow aplasia. It is created by eHealthMe based on reports of 17,723 people who have side effects when taking Mercaptopurine from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.
17,723 people reported to have side effects when taking Mercaptopurine.
Among them, 242 people (1.37%) have Febrile bone marrow aplasia.
What is Mercaptopurine?
Mercaptopurine has active ingredients of mercaptopurine. It is often used in crohn's disease. eHealthMe is studying from 17,983 Mercaptopurine users for its effectiveness, alternative drugs and more.
What is Febrile bone marrow aplasia?
Febrile bone marrow aplasia (bone marrow greatly decreases or stops production of blood cells) is found to be associated with 453 drugs and 375 conditions by eHealthMe.
Number of Mercaptopurine and Febrile bone marrow aplasia reports submitted per year:

Time on Mercaptopurine when people have Febrile bone marrow aplasia *:
Gender of people who have Febrile bone marrow aplasia when taking Mercaptopurine*:
Age of people who have Febrile bone marrow aplasia when taking Mercaptopurine *:
Common drugs people take besides Mercaptopurine *:
Common side effects people have besides Febrile bone marrow aplasia *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Mercaptopurine and have Febrile bone marrow aplasia?
Check whether Febrile bone marrow aplasia is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Alternative drugs to, pros and cons of Mercaptopurine:
- Mercaptopurine (17,983 reports)
Febrile bone marrow aplasia treatments and more:
- Febrile bone marrow aplasia (3,997 reports)
COVID vaccines that are related to Febrile bone marrow aplasia:
- Febrile bone marrow aplasia in Moderna COVID Vaccine
- Febrile bone marrow aplasia in Pfizer BioNTech Covid Vaccine
- Febrile bone marrow aplasia in Johnson and Johnson Covid Vaccine
How severe was Febrile bone marrow aplasia and when was it recovered:
Expand to all the drugs that have ingredients of mercaptopurine:
Common drugs associated with Febrile bone marrow aplasia:
- Bactrim: 429 reports
- Carboplatin: 243 reports
- Cisplatin: 266 reports
- Cyclophosphamide: 725 reports
- Cytarabine: 749 reports
- Dexamethasone: 286 reports
- Docetaxel: 110 reports
- Emend: 109 reports
- Etoposide: 404 reports
- Fluorouracil: 167 reports
- Ifosfamide: 194 reports
- Mercaptopurine: 242 reports
- Methotrexate: 946 reports
- Neulasta: 125 reports
- Ondansetron: 173 reports
- Paracetamol: 249 reports
- Polaramine: 113 reports
- Prednisolone: 130 reports
- Prednisone: 247 reports
- Solu-medrol: 106 reports
- Vincristine sulfate: 202 reports
All the drugs that are associated with Febrile bone marrow aplasia:
- Febrile bone marrow aplasia (453 drugs)
Common conditions associated with Febrile bone marrow aplasia:
- Acute myeloid leukaemia: 140 reports
- Acute myeloid leukaemia aggravated: 152 reports
- Breast cancer: 157 reports
- Chronic lymphocytic leukaemia: 113 reports
- High blood pressure: 111 reports
- Infection: 132 reports
- Leukemia - acute childhood (all): 723 reports
- Multiple myeloma: 117 reports
- Pain: 185 reports
All the conditions that are associated with Febrile bone marrow aplasia:
- Febrile bone marrow aplasia (375 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on mercaptopurine (the active ingredients of Mercaptopurine) and Mercaptopurine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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