Mercaptopurine and Hyperbilirubinaemia - a phase IV clinical study of FDA data
Summary:
Hyperbilirubinaemia is found among people who take Mercaptopurine, especially for people who are male, 10-19 old, have been taking the drug for < 1 month.
The phase IV clinical study analyzes which people take Mercaptopurine and have Hyperbilirubinaemia. It is created by eHealthMe based on reports of 17,723 people who have side effects when taking Mercaptopurine from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.
17,723 people reported to have side effects when taking Mercaptopurine.
Among them, 142 people (0.8%) have Hyperbilirubinaemia.
What is Mercaptopurine?
Mercaptopurine has active ingredients of mercaptopurine. It is often used in crohn's disease. eHealthMe is studying from 17,982 Mercaptopurine users for its effectiveness, alternative drugs and more.
What is Hyperbilirubinaemia?
Hyperbilirubinaemia (excess of bilirubin in the blood) is found to be associated with 1,364 drugs and 996 conditions by eHealthMe.
Number of Mercaptopurine and Hyperbilirubinaemia reports submitted per year:
Time on Mercaptopurine when people have Hyperbilirubinaemia *:
Gender of people who have Hyperbilirubinaemia when taking Mercaptopurine*:
Age of people who have Hyperbilirubinaemia when taking Mercaptopurine *:
Common drugs people take besides Mercaptopurine *:
Common side effects people have besides Hyperbilirubinaemia *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Mercaptopurine and have Hyperbilirubinaemia?
Check whether Hyperbilirubinaemia is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Alternative drugs to, pros and cons of Mercaptopurine:
- Mercaptopurine (17,982 reports)
Hyperbilirubinaemia treatments and more:
- Hyperbilirubinaemia (10,968 reports)
COVID vaccines that are related to Hyperbilirubinaemia:
- Hyperbilirubinaemia in Moderna COVID Vaccine
- Hyperbilirubinaemia in Pfizer BioNTech Covid Vaccine
- Hyperbilirubinaemia in Johnson and Johnson Covid Vaccine
How severe was Hyperbilirubinaemia and when was it recovered:
Expand to all the drugs that have ingredients of mercaptopurine:
Common drugs associated with Hyperbilirubinaemia:
- Acetaminophen: 192 reports
- Acyclovir: 178 reports
- Albuterol: 101 reports
- Aldactone: 174 reports
- Allopurinol: 337 reports
- Amlodipine: 152 reports
- Amoxicillin: 127 reports
- Aspirin: 229 reports
- Augmentin: 110 reports
- Bactrim: 278 reports
- Capecitabine: 184 reports
- Carboplatin: 117 reports
- Ceftazidime: 111 reports
- Cisplatin: 181 reports
- Crixivan: 143 reports
- Cyclophosphamide: 403 reports
- Cyclosporine: 218 reports
- Cytarabine: 535 reports
- Dexamethasone: 292 reports
- Digoxin: 128 reports
- Epivir: 137 reports
- Etoposide: 199 reports
- Famotidine: 153 reports
- Fluconazole: 199 reports
- Fludara: 198 reports
- Fluorouracil: 290 reports
- Folic acid: 105 reports
- Furosemide: 347 reports
- Heparin: 177 reports
- Ibuprofen: 180 reports
- Kaletra: 151 reports
- Lactulose: 110 reports
- Lansoprazole: 166 reports
- Lasix: 319 reports
- Lisinopril: 130 reports
- Loraz: 166 reports
- Lorazepam: 169 reports
- Mercaptopurine: 142 reports
- Meropenem: 136 reports
- Metformin: 233 reports
- Methotrexate: 710 reports
- Metoclopramide: 129 reports
- Metronidazole: 108 reports
- Morphine: 213 reports
- Mycophenolate mofetil: 194 reports
- Nexium: 118 reports
- Norvasc: 102 reports
- Norvir: 359 reports
- Omeprazole: 356 reports
- Oncaspar: 142 reports
- Ondansetron: 237 reports
- Oxaliplatin: 192 reports
- Oxycodone: 131 reports
- Paclitaxel: 109 reports
- Pantoprazole: 293 reports
- Paracetamol: 271 reports
- Prednisolone: 272 reports
- Prednisone: 528 reports
- Ramipril: 123 reports
- Ranitidine: 112 reports
- Rebetol: 118 reports
- Revlimid: 105 reports
- Reyataz: 350 reports
- Ribavirin: 624 reports
- Ritonavir: 144 reports
- Simvastatin: 103 reports
- Sovaldi: 162 reports
- Spironolactone: 153 reports
- Stavudine: 161 reports
- Tacrolimus: 162 reports
- Truvada: 230 reports
- Tylenol: 181 reports
- Vincristine sulfate: 233 reports
- Xeloda: 119 reports
- Zofran: 204 reports
All the drugs that are associated with Hyperbilirubinaemia:
- Hyperbilirubinaemia (1,364 drugs)
Common conditions associated with Hyperbilirubinaemia:
- Acute childhood leukemia: 373 reports
- Acute lymphoblastic anemia: 378 reports
- Acute lymphoblastic leukemia: 373 reports
- Acute lymphocytic leukaemia: 373 reports
- Acute lymphocytic leukemia: 373 reports
- Acute lymphocytic leukemia (all): 378 reports
- Acute myeloid leukaemia: 292 reports
- All: 373 reports
- Antidepressant therapy: 215 reports
- Anxiety: 122 reports
- Blood pressure increased: 426 reports
- Breast cancer: 173 reports
- Cancer - acute childhood leukemia (all): 378 reports
- Carcinoma - ductal: 180 reports
- Carcinoma - lobular: 172 reports
- Chronic myeloid leukaemia: 158 reports
- Constipation: 136 reports
- Depression: 218 reports
- Fever: 126 reports
- Hbp: 426 reports
- Hepatitis c: 541 reports
- High blood pressure: 426 reports
- Hiv: 643 reports
- Hiv antibody positive: 655 reports
- Hiv infection: 646 reports
- Hiv test: 643 reports
- Human immunodeficiency virus infection: 643 reports
- Hypertension: 426 reports
- Leukemia - acute childhood (all): 373 reports
- Nausea: 225 reports
- Pain: 300 reports
- Pain management: 295 reports
- Preventive health care: 299 reports
- Stress and anxiety: 122 reports
- Type 2 diabetes: 115 reports
All the conditions that are associated with Hyperbilirubinaemia:
- Hyperbilirubinaemia (996 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on mercaptopurine (the active ingredients of Mercaptopurine) and Mercaptopurine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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