Mercaptopurine and Pneumatosis intestinalis - a phase IV clinical study of FDA data
Summary:
We study 21,456 people who have side effects when taking Mercaptopurine. Pneumatosis intestinalis is found, especially among people who are female, 2-9 old, have been taking the drug for < 1 month, also take Oncaspar and have Acute lymphocytic leukemia (all).
The phase IV clinical study analyzes which people take Mercaptopurine and have Pneumatosis intestinalis. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
21,456 people reported to have side effects when taking Mercaptopurine.
Among them, 172 people (0.8%) have Pneumatosis intestinalis.
What is Mercaptopurine?
Mercaptopurine has active ingredients of mercaptopurine. It is used in crohn's disease. Currently, eHealthMe is studying from 21,724 Mercaptopurine users.
What is Pneumatosis intestinalis?
Pneumatosis intestinalis (air or gas in an intestine) is found to be associated with 564 drugs and 465 conditions by eHealthMe. Currently, we are studying 2,869 people who have Pneumatosis intestinalis.
Number of Mercaptopurine and Pneumatosis intestinalis reports submitted per year:
Time on Mercaptopurine when people have Pneumatosis intestinalis *:
Gender of people who have Pneumatosis intestinalis when taking Mercaptopurine*:
Age of people who have Pneumatosis intestinalis when taking Mercaptopurine *:
Common drugs people take besides Mercaptopurine *:
Common side effects people have besides Pneumatosis intestinalis *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Mercaptopurine and have Pneumatosis intestinalis?
Check whether Pneumatosis intestinalis is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- O'rafferty C, McElligott F, Storey L, O'marcaigh A, Smith O, "Pneumatosis intestinalis and imatinib mesylate", Annals of hematology, 2014 Oct .
Related studies
Mercaptopurine side effects by duration, gender and age:
- Mercaptopurine side effects (21,724 reports)
Pneumatosis intestinalis treatments and more:
- Pneumatosis intestinalis (2,869 reports)
Common drugs associated with Pneumatosis intestinalis:
- Prednisolone: 359 reports
- Prednisone: 342 reports
- Tacrolimus: 322 reports
- Methotrexate: 300 reports
- Cyclophosphamide: 294 reports
- Mycophenolate mofetil: 249 reports
- Etoposide: 227 reports
- Methylprednisolone: 196 reports
- Cytarabine: 193 reports
- Mercaptopurine: 172 reports
All the drugs that are associated with Pneumatosis intestinalis:
- Pneumatosis intestinalis (564 drugs)
Common conditions associated with Pneumatosis intestinalis:
- Acute lymphocytic leukemia (all): 232 reports
All the conditions that are associated with Pneumatosis intestinalis:
- Pneumatosis intestinalis (465 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on mercaptopurine (the active ingredients of Mercaptopurine) and Mercaptopurine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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