Metaxalone and Nail discolouration - a phase IV clinical study of FDA data


Nail discolouration is reported only by a few people who take Metaxalone.

The phase IV clinical study analyzes which people take Metaxalone and have Nail discolouration. It is created by eHealthMe based on reports of 3,664 people who have side effects while taking Metaxalone from the FDA, and is updated regularly.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On Jul, 30, 2022

3,664 people reported to have side effects when taking Metaxalone.
Among them, 2 people (0.05%) have Nail discolouration.

What is Metaxalone?

Metaxalone has active ingredients of metaxalone. It is often used in back pain - low. eHealthMe is studying from 3,829 Metaxalone users for its effectiveness, alternative drugs and more.

What is Nail discolouration?

Nail discolouration (change in nail colour) is found to be associated with 1,276 drugs and 894 conditions by eHealthMe.

Number of Metaxalone and Nail discolouration reports submitted per year:

Could Metaxalone cause Nail discolouration?

Gender of people who have Nail discolouration when taking Metaxalone *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Nail discolouration when taking Metaxalone *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 50 %
  • 50-59: 50 %
  • 60+: 0.0 %

Common drugs people take besides Metaxalone *:

  1. Zolpidem Tartrate: 1 person, 50.00%
  2. Vitamin D2: 1 person, 50.00%
  3. Tylenol: 1 person, 50.00%
  4. Pilocarpine Hydrochloride: 1 person, 50.00%
  5. Myrbetriq: 1 person, 50.00%
  6. Methotrexate Sodium: 1 person, 50.00%
  7. Levothyroxine Sodium: 1 person, 50.00%
  8. Leflunomide: 1 person, 50.00%
  9. Imodium: 1 person, 50.00%
  10. Humira: 1 person, 50.00%

Common side effects people have besides Nail discolouration *:

  1. Fall: 2 people, 100.00%
  2. Weight Increased: 1 person, 50.00%
  3. Weakness: 1 person, 50.00%
  4. Anger: 1 person, 50.00%
  5. Back Injury: 1 person, 50.00%
  6. Constipation: 1 person, 50.00%
  7. Diarrhea: 1 person, 50.00%
  8. Dizziness: 1 person, 50.00%
  9. Drowsiness: 1 person, 50.00%
  10. Excoriation (to tear or wear off the skin of): 1 person, 50.00%

Common conditions people have *:

  1. Tremor (trembling or shaking movements in one or more parts of your body): 1 person, 50.00%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 50.00%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 50.00%

* Approximation only. Some reports may have incomplete information.

Do you take Metaxalone and have Nail discolouration?

Check whether Nail discolouration is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Alternative drugs to, pros and cons of Metaxalone:

Nail discolouration treatments and more:

COVID vaccines that are related to Nail discolouration:

How severe was Nail discolouration and when was it recovered:

Expand to all the drugs that have ingredients of metaxalone:

Common drugs associated with Nail discolouration:

All the drugs that are associated with Nail discolouration:

Common conditions associated with Nail discolouration:

All the conditions that are associated with Nail discolouration:

How the study uses the data?

The study uses data from the FDA. It is based on metaxalone (the active ingredients of Metaxalone) and Metaxalone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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