Metformin and Coughing up blood - a phase IV clinical study of FDA data
Summary:
Coughing up blood is found among people who take Metformin, especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months.
The phase IV clinical study analyzes which people take Metformin and have Coughing up blood. It is created by eHealthMe based on reports of 363,447 people who have side effects when taking Metformin from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.
On Jun, 30, 2022
363,447 people reported to have side effects when taking Metformin.
Among them, 692 people (0.19%) have Coughing up blood.
What is Metformin?
Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 373,350 Metformin users for its effectiveness, alternative drugs and more.
What is Coughing up blood?
Coughing up blood is found to be associated with 2,433 drugs and 1,914 conditions by eHealthMe.
Number of Metformin and Coughing up blood reports submitted per year:
Time on Metformin when people have Coughing up blood *:
Gender of people who have Coughing up blood when taking Metformin*:
Age of people who have Coughing up blood when taking Metformin *:
Common drugs people take besides Metformin *:
Common side effects people have besides Coughing up blood *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Metformin and have Coughing up blood?
Check whether Coughing up blood is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- T.Audi Yanto, I.Huang, F.Nathania Kosasih, NP Hardjo Lugito, "Nightmare and Abnormal Dreams: Rare Side Effects of Metformin?", Case Reports in Endocrinology, 2018 Jan .
- Al-Hamdy RA, "Assessment of electrolytes and HbA1c in type 2 diabetic patients using metformin and evaluation of guidelines obedience regarding renal impairment", J.Thi-Qar Sci., 2015 Jan .
- Wiwanitkit S, Wiwanitkit V, "Metformin and sleep disorders", Indian journal of endocrinology and metabolism, 2012 Jan .
Related studies
Alternative drugs to, pros and cons of Metformin:
- Metformin (373,350 reports)
Coughing up blood treatments and more:
- Coughing up blood (30,726 reports)
COVID vaccines that are related to Coughing up blood:
- Coughing up blood in Moderna COVID Vaccine
- Coughing up blood in Pfizer BioNTech Covid Vaccine
- Coughing up blood in Johnson and Johnson Covid Vaccine
How severe was Coughing up blood and when was it recovered:
Expand to all the drugs that have ingredients of metformin hydrochloride:
Common drugs associated with Coughing up blood:
- Abraxane: 102 reports
- Acetaminophen: 306 reports
- Acetylsalicylic acid: 677 reports
- Actemra: 102 reports
- Acyclovir: 124 reports
- Adcirca: 458 reports
- Adempas: 382 reports
- Advair diskus 100/50: 240 reports
- Advair hfa: 360 reports
- Afinitor: 105 reports
- Albuterol: 999 reports
- Albuterol sulfate: 156 reports
- Aldactone: 277 reports
- Aleve: 114 reports
- Alimta: 119 reports
- Allegra: 129 reports
- Allopurinol: 692 reports
- Alprazolam: 273 reports
- Alvesco: 131 reports
- Ambien: 340 reports
- Amlodipine: 777 reports
- Amlodipine besylate: 112 reports
- Amoxicillin: 373 reports
- Apixaban: 223 reports
- Aranesp: 143 reports
- Aredia: 276 reports
- Asa: 147 reports
- Aspirin: 2,332 reports
- Atenolol: 452 reports
- Ativan: 255 reports
- Atorvastatin calcium: 133 reports
- Atrovent: 336 reports
- Augmentin: 219 reports
- Avastin: 429 reports
- Avelox: 141 reports
- Azathioprine: 154 reports
- Azithromycin: 183 reports
- Baclofen: 108 reports
- Bactrim: 259 reports
- Benadryl: 279 reports
- Budesonide: 135 reports
- Calcium: 294 reports
- Carboplatin: 829 reports
- Cardizem: 115 reports
- Carvedilol: 319 reports
- Cayston: 229 reports
- Ceftriaxone: 135 reports
- Celebrex: 359 reports
- Celexa: 182 reports
- Centrum: 159 reports
- Chantix: 101 reports
- Cipro: 115 reports
- Cisplatin: 495 reports
- Clarithromycin: 222 reports
- Claritin: 181 reports
- Clonazepam: 250 reports
- Clonidine: 161 reports
- Clopidogrel: 453 reports
- Clopidogrel bisulfate: 105 reports
- Clopra: 210 reports
- Codeine: 126 reports
- Colace: 230 reports
- Combivent: 235 reports
- Cordarone: 129 reports
- Coreg: 228 reports
- Coumadin: 1,168 reports
- Cozaar: 126 reports
- Creon: 273 reports
- Crestor: 307 reports
- Cyclophosphamide: 264 reports
- Cyclosporine: 108 reports
- Cymbalta: 200 reports
- Cytarabine: 192 reports
- Decadron: 332 reports
- Dexamethasone: 435 reports
- Diazepam: 247 reports
- Diflucan: 144 reports
- Digoxin: 566 reports
- Dilaudid: 185 reports
- Diovan: 183 reports
- Docetaxel: 213 reports
- Doxycycline: 277 reports
- Duoneb: 125 reports
- Duragesic: 160 reports
- Duragesic-100: 121 reports
- Effexor: 201 reports
- Elavil: 118 reports
- Eliquis: 587 reports
- Enbrel: 363 reports
- Enoxaparin sodium: 103 reports
- Esbriet: 141 reports
- Escitalopram: 115 reports
- Etoposide: 189 reports
- Famotidine: 243 reports
- Fentanyl: 222 reports
- Finasteride: 117 reports
- Fish oil: 210 reports
- Flexeril: 143 reports
- Flolan: 235 reports
- Flomax: 227 reports
- Flonase: 276 reports
- Flovent: 203 reports
- Fluconazole: 246 reports
- Fluorouracil: 158 reports
- Fluoxetine: 155 reports
- Fluticasone propionate: 120 reports
- Folic acid: 336 reports
- Fosamax: 308 reports
- Furosemide: 1,296 reports
- Gabapentin: 584 reports
- Gemcitabine: 155 reports
- Gemzar: 148 reports
- Glipizide: 184 reports
- Glucophage: 143 reports
- Glyburide: 118 reports
- Guaifenesin: 107 reports
- Heparin: 679 reports
- Heparin sodium: 134 reports
- Humalog: 164 reports
- Humira: 733 reports
- Hydrochlorothiazide: 434 reports
- Ibu: 542 reports
- Ibuprofen: 540 reports
- Imbruvica: 263 reports
- Imdur: 119 reports
- Imodium: 111 reports
- Insulin: 120 reports
- Ipratropium bromide: 131 reports
- Iressa: 121 reports
- Isosorbide mononitrate: 127 reports
- Keflex: 130 reports
- Keytruda: 142 reports
- Klonopin: 152 reports
- Klor-con: 137 reports
- Lactulose: 178 reports
- Lansoprazole: 513 reports
- Lantus: 285 reports
- Lasix: 1,090 reports
- Letairis: 396 reports
- Letrozole: 102 reports
- Levaquin: 404 reports
- Levofloxacin: 108 reports
- Levothyroxine sodium: 295 reports
- Lexapro: 217 reports
- Lipitor: 662 reports
- Lisinopril: 919 reports
- Lopressor: 153 reports
- Lopurin: 692 reports
- Loratadine: 127 reports
- Loraz: 423 reports
- Lorazepam: 423 reports
- Lortab: 202 reports
- Losartan: 297 reports
- Lovenox: 372 reports
- Lyrica: 354 reports
- Lys: 157 reports
- Lysine: 157 reports
- Magnesium: 238 reports
- Melatonin: 102 reports
- Meropenem: 127 reports
- Metformin: 692 reports
- Methotrexate: 711 reports
- Methylprednisolone: 117 reports
- Metoclopramide: 210 reports
- Metoprolol succinate: 185 reports
- Metoprolol tartrate: 294 reports
- Metronidazole: 114 reports
- Miralax: 203 reports
- Morphine: 575 reports
- Morphine sulfate: 208 reports
- Motrin: 109 reports
- Ms contin: 138 reports
- Mucinex: 230 reports
- Multivitamin: 196 reports
- Mycophenolate mofetil: 162 reports
- Naproxen: 124 reports
- Nasonex: 145 reports
- Navelbine: 120 reports
- Neurontin: 366 reports
- Nexavar: 170 reports
- Nexium: 659 reports
- Nifedipine: 128 reports
- Nitroglycerin: 324 reports
- Norco: 168 reports
- Norvasc: 382 reports
- Novolog: 113 reports
- Nuvaring: 158 reports
- Nystatin: 134 reports
- Ofev: 156 reports
- Omeprazole: 1,113 reports
- Ondansetron: 258 reports
- Opdivo: 101 reports
- Opsumit: 516 reports
- Orkambi: 145 reports
- Oxycodone: 343 reports
- Oxycontin: 350 reports
- Paclitaxel: 375 reports
- Pantoprazole: 700 reports
- Pantoprazole sodium: 120 reports
- Paracetamol: 366 reports
- Paroxetine: 111 reports
- Paxil: 176 reports
- Pegasys: 177 reports
- Pemetrexed: 119 reports
- Pepcid: 157 reports
- Percocet: 264 reports
- Phenergan: 129 reports
- Plaquenil: 125 reports
- Plavix: 811 reports
- Potassium: 183 reports
- Pradaxa: 733 reports
- Prednisolone: 569 reports
- Prednisone: 1,727 reports
- Pregabalin: 146 reports
- Premarin: 134 reports
- Prevacid: 278 reports
- Prilosec: 523 reports
- Proair hfa: 180 reports
- Profen: 549 reports
- Prograf: 106 reports
- Propofol: 111 reports
- Protonix: 398 reports
- Prozac: 188 reports
- Pulmicort: 250 reports
- Pulmozyme: 538 reports
- Ramipril: 303 reports
- Ranitidine: 353 reports
- Reglan: 154 reports
- Remicade: 163 reports
- Remodulin: 358 reports
- Reopro: 113 reports
- Revatio: 327 reports
- Revlimid: 403 reports
- Ribavirin: 218 reports
- Rituxan: 138 reports
- Rivaroxaban: 177 reports
- Rocephin: 126 reports
- Sandostatin: 162 reports
- Sandostatin lar: 124 reports
- Senna: 145 reports
- Serevent: 127 reports
- Seroquel: 122 reports
- Sertraline: 189 reports
- Sildenafil citrate: 140 reports
- Simvastatin: 818 reports
- Singulair: 572 reports
- Soliris: 101 reports
- Solu-medrol: 165 reports
- Spiriva: 877 reports
- Spironolactone: 466 reports
- Sutent: 253 reports
- Symbicort: 618 reports
- Synthroid: 582 reports
- Tacrolimus: 215 reports
- Tadalafil: 103 reports
- Tamsulosin: 155 reports
- Tarceva: 270 reports
- Taxol: 237 reports
- Taxotere: 262 reports
- Temaz: 114 reports
- Temazepam: 114 reports
- Theophylline: 139 reports
- Tobi: 318 reports
- Tobi podhaler: 136 reports
- Toprol-xl: 183 reports
- Torsemide: 120 reports
- Tracleer: 464 reports
- Tramadol: 364 reports
- Tylenol: 626 reports
- Tyvaso: 311 reports
- Valium: 111 reports
- Valsartan: 141 reports
- Velcade: 164 reports
- Veletri: 193 reports
- Ventavis: 126 reports
- Ventolin: 348 reports
- Vfend: 101 reports
- Vicodin: 322 reports
- Vioxx: 331 reports
- Vitamin b12: 173 reports
- Vitamin c: 173 reports
- Vitamin d: 526 reports
- Vitamin d3: 222 reports
- Vitamin e: 150 reports
- Vitamins: 232 reports
- Voltaren: 118 reports
- Voriconazole: 131 reports
- Votrient: 106 reports
- Warfarin sodium: 686 reports
- Wellbutrin: 180 reports
- Xanax: 414 reports
- Xarelto: 2,535 reports
- Xeljanz: 104 reports
- Xolair: 304 reports
- Yasmin: 109 reports
- Zantac: 298 reports
- Zide: 435 reports
- Zithromax: 232 reports
- Zocor: 330 reports
- Zofran: 398 reports
- Zoloft: 298 reports
- Zolpidem: 232 reports
- Zometa: 529 reports
- Zopiclone: 142 reports
- Zyprexa: 105 reports
- Zyrtec: 218 reports
All the drugs that are associated with Coughing up blood:
- Coughing up blood (2,433 drugs)
Common conditions associated with Coughing up blood:
- Acid reflux: 425 reports
- Acupuncture and pain: 553 reports
- Acute myeloid leukaemia: 167 reports
- Adult hypothyroidism: 197 reports
- A-fib: 2,454 reports
- Agrypnia: 217 reports
- Anaemia: 154 reports
- Ankylosing spondylitis: 126 reports
- Anticoagulant therapy: 326 reports
- Antidepressant therapy: 403 reports
- Anxiety: 280 reports
- Anxiety and stress: 280 reports
- Apprehension: 280 reports
- Arrhythmia: 105 reports
- Arteriosclerotic heart disease: 180 reports
- Arthritis: 133 reports
- Asthma: 886 reports
- Atrial fibrillation: 2,454 reports
- Atrial fibrillation/flutter: 2,454 reports
- Atrial flutter: 2,454 reports
- Auricular fibrillation: 2,454 reports
- Back pain: 222 reports
- Birth control: 233 reports
- Blood cholesterol abnormal: 493 reports
- Blood cholesterol increased: 493 reports
- Blood clot in the legs: 610 reports
- Blood pressure - high: 1,174 reports
- Blood pressure increased: 1,174 reports
- Blood triglycerides abnormal: 493 reports
- Blood triglycerides increased: 493 reports
- Breast cancer: 172 reports
- Breast cancer aggravated: 172 reports
- Breast cancer metastatic: 143 reports
- Breathing difficulty: 189 reports
- Bronchitis: 123 reports
- Bronchopneumonia: 198 reports
- Cad: 170 reports
- Cancer - breast: 169 reports
- Cancer - kidney: 291 reports
- Cancer - prostate: 136 reports
- Cannot sleep: 205 reports
- Cardiac disorder: 165 reports
- Cardiac failure: 123 reports
- Cerebrovascular accident: 1,430 reports
- Cfa: 346 reports
- Chronic asthma: 875 reports
- Chronic lymphocytic leukaemia: 283 reports
- Chronic obstructive airway disease: 517 reports
- Chronic obstructive lung disease: 517 reports
- Chronic obstructive pulmonary disease: 517 reports
- Constipation: 253 reports
- Constipation aggravated: 253 reports
- Contraception: 233 reports
- Copd: 517 reports
- Coronary artery disease aggravated: 170 reports
- Coronary heart disease: 170 reports
- Cough: 241 reports
- Cough aggravated: 241 reports
- Coughing: 241 reports
- Crohns: 225 reports
- Crohn's disease: 225 reports
- Crohns disease: 225 reports
- Crohn's disease aggravated: 225 reports
- Cva: 1,450 reports
- Cystic fibrosis: 827 reports
- Deep vein thrombosis: 610 reports
- Deep venous thrombosis: 610 reports
- Depression: 403 reports
- Diabetes: 327 reports
- Diabetes mellitus: 331 reports
- Diabetes mellitus management: 327 reports
- Diarrhea: 113 reports
- Diarrhea aggravated: 113 reports
- Diarrhoea: 113 reports
- Difficulty breathing: 189 reports
- Difficulty falling asleep: 212 reports
- Difficulty in breathing: 189 reports
- Dm: 327 reports
- Dvt: 612 reports
- Dyslipidemia: 493 reports
- Dyspnea exacerbated: 189 reports
- Dyssomnia: 212 reports
- Excessive sleepiness: 157 reports
- Exercise-induced asthma: 875 reports
- Family planning and contraception: 232 reports
- Feeling uptight: 280 reports
- Fever: 142 reports
- Gastritis: 111 reports
- Gastroesophageal reflux disease: 425 reports
- Gastrooesophageal reflux disease: 425 reports
- Gerd: 425 reports
- Granulomatous ileocolitis: 225 reports
- Hbp: 1,174 reports
- Headache: 124 reports
- Hepatitis c: 358 reports
- High blood cholesterol: 493 reports
- High blood cholesterol and triglycerides: 493 reports
- High blood pressure: 1,174 reports
- High cholesterol: 477 reports
- Hiv infection: 120 reports
- Htn: 1,174 reports
- Human immunodeficiency virus infection: 119 reports
- Hypercholesterolaemia: 493 reports
- Hypercholesterolemia: 493 reports
- Hyperlipidaemia: 128 reports
- Hyperlipidemia: 493 reports
- Hyperlipoproteinemia: 493 reports
- Hypernephroma: 291 reports
- Hypersensitivity: 114 reports
- Hypertension: 1,178 reports
- Hypothyroid: 197 reports
- Hypothyroidism: 197 reports
- Idiopathic pulmonary fibrosis: 346 reports
- Ileitis: 225 reports
- Infection: 184 reports
- Insomnia: 212 reports
- Insomnia exacerbated: 212 reports
- Insomnolence: 212 reports
- Ipf: 346 reports
- Irregularity of bowels: 242 reports
- Jitters: 280 reports
- Joint pain: 101 reports
- Kidney transplant: 114 reports
- Lack of regular bowel movements: 242 reports
- Ldl/hdl ratio increased: 493 reports
- Lipid test: 493 reports
- Lipoprotein test: 493 reports
- Low thyroid: 197 reports
- Lung adenocarcinoma: 186 reports
- Lung cancer - non-small cell: 1,067 reports
- Lung neoplasm malignant: 423 reports
- Metastases to bone: 120 reports
- Metastatic renal cell carcinoma: 188 reports
- Ms: 362 reports
- Ms hug: 362 reports
- Multiple myeloma: 537 reports
- Multiple sclerosis: 362 reports
- Myeloma - multiple: 537 reports
- Myxedema: 184 reports
- Nausea: 246 reports
- Niddm: 155 reports
- Non-a or non-b hepatitis: 358 reports
- Non-small cell lung cancer: 1,075 reports
- Nonspecific back pain: 222 reports
- Osteoporosis: 335 reports
- Pain: 883 reports
- Pain exacerbated: 883 reports
- Pain management: 847 reports
- Pain relief by acupuncture: 847 reports
- Peptic esophagitis: 413 reports
- Plaque psoriasis: 288 reports
- Plasma cell myeloma: 537 reports
- Pneumonia: 200 reports
- Pneumonitis: 198 reports
- Preventive health care: 377 reports
- Primary myelofibrosis: 112 reports
- Primary pulmonary hypertension: 1,457 reports
- Prostate cancer: 140 reports
- Pseudomonas infection: 170 reports
- Psoriasis: 288 reports
- Psoriatic arthropathy: 182 reports
- Psoriatic arthropathy aggravated: 182 reports
- Pulmonary arterial hypertension: 1,457 reports
- Pulmonary embolism: 631 reports
- Pulmonary embolus: 657 reports
- Pulmonary fibrosis: 346 reports
- Pulmonary hypertension: 665 reports
- Ra: 1,002 reports
- Reflux: 425 reports
- Regional enteritis: 225 reports
- Renal cancer: 291 reports
- Renal cell carcinoma: 291 reports
- Renal transplant: 114 reports
- Rheumatoid arthritis: 1,002 reports
- Short of breath: 189 reports
- Sleep disorder: 157 reports
- Sleep disorder due to general medical condition, insomnia type: 157 reports
- Sleep disorder therapy: 157 reports
- Sleeping difficulty: 212 reports
- Sleeplessness: 212 reports
- Spondylitis: 126 reports
- Stiffness in a joint: 101 reports
- Stress: 280 reports
- Stress and anxiety: 280 reports
- Stroke: 1,450 reports
- Supplementation therapy: 110 reports
- Tension: 280 reports
- Thin bones: 322 reports
- Thrombosis: 1,363 reports
- Transplant - kidney: 114 reports
- Type 2 diabetes: 149 reports
- Type 2 diabetes mellitus: 155 reports
- Uip: 346 reports
- Underactive thyroid: 197 reports
All the conditions that are associated with Coughing up blood:
- Coughing up blood (1,914 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on metformin hydrochloride (the active ingredients of Metformin) and Metformin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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