Who have Diabetes with Metformin - from FDA reports


Diabetes is found among people who take Metformin, especially for people who are female, 60+ old , have been taking the drug for 1 - 6 months, also take medication Seroquel, and have High blood pressure. This study is created by eHealthMe based on reports of 240,947 people who have side effects when taking Metformin from FDA, and is updated regularly.

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On Dec, 25, 2018

240,947 people reported to have side effects when taking Metformin.
Among them, 4,177 people (1.73%) have Diabetes


Number of reports submitted per year:

Could Metformin cause Diabetes?

Time on Metformin when people have Diabetes *:

  • < 1 month: 19.09 %
  • 1 - 6 months: 24.55 %
  • 6 - 12 months: 10.91 %
  • 1 - 2 years: 10.0 %
  • 2 - 5 years: 20.91 %
  • 5 - 10 years: 9.09 %
  • 10+ years: 5.45 %

Gender of people who have Diabetes when taking Metformin *:

  • female: 59.27 %
  • male: 40.73 %

Age of people who have Diabetes when taking Metformin *:

  • 0-1: 0.1 %
  • 2-9: 0.16 %
  • 10-19: 0.64 %
  • 20-29: 2.32 %
  • 30-39: 8.32 %
  • 40-49: 19.7 %
  • 50-59: 28.25 %
  • 60+: 40.5 %

Top conditions involved for these people *:

  1. High Blood Pressure: 638 people, 15.27%
  2. Depression: 567 people, 13.57%
  3. High Blood Cholesterol: 495 people, 11.85%
  4. Stress And Anxiety: 318 people, 7.61%
  5. Pain: 288 people, 6.89%
  6. Bipolar Disorder (mood disorder): 269 people, 6.44%
  7. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 250 people, 5.99%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 243 people, 5.82%
  9. Sleep Disorder: 225 people, 5.39%
  10. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 224 people, 5.36%

Top co-used drugs for these people *:

  1. Seroquel: 639 people, 15.30%
  2. Lipitor: 512 people, 12.26%
  3. Aspirin: 446 people, 10.68%
  4. Lisinopril: 420 people, 10.06%
  5. Nexium: 383 people, 9.17%
  6. Crestor: 305 people, 7.30%
  7. Lantus: 304 people, 7.28%
  8. Simvastatin: 292 people, 6.99%
  9. Lyrica: 269 people, 6.44%
  10. Zyprexa: 252 people, 6.03%

Top other side effects for these people *:

  1. High Blood Pressure: 881 people, 21.09%
  2. Pain: 506 people, 12.11%
  3. Fatigue (feeling of tiredness): 467 people, 11.18%
  4. Breathing Difficulty: 437 people, 10.46%
  5. High Blood Cholesterol: 429 people, 10.27%
  6. Nausea (feeling of having an urge to vomit): 396 people, 9.48%
  7. Stress And Anxiety: 365 people, 8.74%
  8. Dizziness: 351 people, 8.40%
  9. Weight Increased: 351 people, 8.40%
  10. Drug Ineffective: 345 people, 8.26%

* Approximation only. Some reports may have incomplete information.

FDA reports used in this study



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Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+


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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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