Metformin and Flatulence - a phase IV clinical study of FDA data

Summary:

Flatulence is found among people who take Metformin, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Metformin and have Flatulence. It is created by eHealthMe based on reports of 395,495 people who have side effects when taking Metformin from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On May, 11, 2023

395,495 people reported to have side effects when taking Metformin.
Among them, 2,185 people (0.55%) have Flatulence.

What is Metformin?

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 406,224 Metformin users for its effectiveness, alternative drugs and more.

What is Flatulence?

Flatulence (flatus expelled through the anus) is found to be associated with 2,632 drugs and 1,863 conditions by eHealthMe.

Number of Metformin and Flatulence reports submitted per year:

* Approximation only. Some reports may have incomplete information.

Do you take Metformin and have Flatulence?

Check whether Flatulence is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

T.Audi Yanto, I.Huang, F.Nathania Kosasih, NP Hardjo Lugito, "Nightmare and Abnormal Dreams: Rare Side Effects of Metformin?", Case Reports in Endocrinology, 2018 Jan .
Al-Hamdy RA, "Assessment of electrolytes and HbA1c in type 2 diabetic patients using metformin and evaluation of guidelines obedience regarding renal impairment", J.Thi-Qar Sci., 2015 Jan .
Wiwanitkit S, Wiwanitkit V, "Metformin and sleep disorders", Indian journal of endocrinology and metabolism, 2012 Jan .

Related studies

How severe was Flatulence and when was it recovered:

Flatulence in Metformin

Expand to all the drugs that have ingredients of metformin hydrochloride:

Flatulence and drugs with ingredients of metformin hydrochloride (2,393 reports)

Alternative drugs to, pros and cons of Metformin:

Metformin (406,224 reports)

Common Metformin side effects:

Diarrhea: 25,489 reports
Fatigue (feeling of tiredness): 22,049 reports
Drug ineffective: 20,041 reports
Nausea and vomiting: 17,857 reports
Weight decreased: 17,682 reports
Breathing difficulty: 16,617 reports

Browse all side effects of Metformin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Flatulence treatments and more:

Flatulence (61,500 reports)

COVID vaccines that are related to Flatulence:

Common drugs associated with Flatulence:

All the drugs that are associated with Flatulence:

Flatulence (2,632 drugs)

Common conditions associated with Flatulence:

High blood pressure: 2,539 reports
High blood cholesterol: 2,496 reports
Crohn's disease: 1,971 reports
Type 2 diabetes: 1,924 reports
Multiple sclerosis: 1,759 reports
Gastroesophageal reflux disease: 1,629 reports
Quit smoking: 1,528 reports

All the conditions that are associated with Flatulence:

Flatulence (1,863 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on metformin hydrochloride (the active ingredients of Metformin) and Metformin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.