Metformin and Gallstones - a phase IV clinical study of FDA data
We study 395,495 people who have side effects when taking Metformin. Gallstones is found, especially among people who are female, 60+ old, have been taking the drug for < 1 month, also take Yasmin and have High blood pressure.
The phase IV clinical study analyzes which people take Metformin and have Gallstones. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
395,495 people reported to have side effects when taking Metformin.
Among them, 2,140 people (0.54%) have Gallstones.
What is Metformin?
Metformin has active ingredients of metformin hydrochloride. It is used in diabetes. Currently, eHealthMe is studying from 440,868 Metformin users.
What is Gallstones?
Gallstones (stone formation by bile component) is found to be associated with 2,911 drugs and 2,059 conditions by eHealthMe. Currently, we are studying 48,349 people who have Gallstones.
Number of Metformin and Gallstones reports submitted per year:
Time on Metformin when people have Gallstones *:
Gender of people who have Gallstones when taking Metformin*:
Age of people who have Gallstones when taking Metformin *:
Common drugs people take besides Metformin *:
Common side effects people have besides Gallstones *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Metformin and have Gallstones?Check whether Gallstones is associated with a drug or a condition
How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- T.Audi Yanto, I.Huang, F.Nathania Kosasih, NP Hardjo Lugito, "Nightmare and Abnormal Dreams: Rare Side Effects of Metformin?", Case Reports in Endocrinology, 2018 Jan .
- Al-Hamdy RA, "Assessment of electrolytes and HbA1c in type 2 diabetic patients using metformin and evaluation of guidelines obedience regarding renal impairment", J.Thi-Qar Sci., 2015 Jan .
- Wiwanitkit S, Wiwanitkit V, "Metformin and sleep disorders", Indian journal of endocrinology and metabolism, 2012 Jan .
Metformin side effects by duration, gender and age:
- Metformin side effects (440,868 reports)
Gallstones treatments and more:
- Gallstones (48,349 reports)
Common drugs associated with Gallstones:
- Yasmin: 5,611 reports
- Yaz: 5,016 reports
- Aspirin: 2,291 reports
- Prednisone: 2,220 reports
- Metformin: 2,140 reports
- Humira: 2,012 reports
- Ibu: 1,926 reports
- Profen: 1,885 reports
- Ibuprofen: 1,865 reports
- Methotrexate: 1,686 reports
All the drugs that are associated with Gallstones:
- Gallstones (2,911 drugs)
Common conditions associated with Gallstones:
- Birth control: 3,414 reports
- High blood pressure: 3,234 reports
- Rheumatoid arthritis: 2,737 reports
- Multiple sclerosis: 2,269 reports
- Pain: 2,023 reports
All the conditions that are associated with Gallstones:
- Gallstones (2,059 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on metformin hydrochloride (the active ingredients of Metformin) and Metformin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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