Methimazole and Basedow's disease - a phase IV clinical study of FDA data
Summary:
Basedow's disease is found among people who take Methimazole, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years.
The phase IV clinical study analyzes which people take Methimazole and have Basedow's disease. It is created by eHealthMe based on reports of 5,705 people who have side effects when taking Methimazole from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
5,705 people reported to have side effects when taking Methimazole.
Among them, 118 people (2.07%) have Basedow's disease.
What is Methimazole?
Methimazole has active ingredients of methimazole. It is often used in hyperthyroidism. eHealthMe is studying from 6,255 Methimazole users for its effectiveness, alternative drugs and more.
What is Basedow's disease?
Basedow's disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones) is found to be associated with 752 drugs and 382 conditions by eHealthMe.
Number of Methimazole and Basedow's disease reports submitted per year:

Time on Methimazole when people have Basedow's disease *:
Gender of people who have Basedow's disease when taking Methimazole*:
Age of people who have Basedow's disease when taking Methimazole *:
Common drugs people take besides Methimazole *:
Common side effects people have besides Basedow's disease *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Methimazole and have Basedow's disease?
Check whether Basedow's disease is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Basedow's disease and when was it recovered:
Expand to all the drugs that have ingredients of methimazole:
Alternative drugs to, pros and cons of Methimazole:
- Methimazole (6,255 reports)
Common Methimazole side effects:
- Drug ineffective: 348 reports
- Fatigue (feeling of tiredness): 320 reports
- Hyperthyroidism (over activity of the thyroid gland): 282 reports
- Weakness: 271 reports
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 262 reports
- Rashes (redness): 250 reports
- Headache (pain in head): 249 reports
- Breathing difficulty: 239 reports
Browse all side effects of Methimazole:
a b c d e f g h i j k l m n o p q r s t u v w x y zBasedow's disease treatments and more:
- Basedow's disease (5,952 reports)
COVID vaccines that are related to Basedow's disease:
- Basedow's disease in Moderna COVID Vaccine
- Basedow's disease in Pfizer BioNTech Covid Vaccine
- Basedow's disease in Johnson and Johnson Covid Vaccine
Common drugs associated with Basedow's disease:
- Synthroid: 187 reports
- Lemtrada: 138 reports
- Prednisone: 124 reports
- Methimazole: 118 reports
All the drugs that are associated with Basedow's disease:
- Basedow's disease (752 drugs)
Common conditions associated with Basedow's disease:
- Multiple sclerosis: 465 reports
- Primary pulmonary hypertension: 114 reports
All the conditions that are associated with Basedow's disease:
- Basedow's disease (382 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on methimazole (the active ingredients of Methimazole) and Methimazole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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