Methotrexate and Bladder discomfort - a phase IV clinical study of FDA data
Bladder discomfort is found among people who take Methotrexate, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months.
The phase IV clinical study analyzes which people take Methotrexate and have Bladder discomfort. It is created by eHealthMe based on reports of 517,446 people who have side effects when taking Methotrexate from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
517,446 people reported to have side effects when taking Methotrexate.
Among them, 30 people (0.01%) have Bladder discomfort.
What is Methotrexate?
Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. eHealthMe is studying from 475,317 Methotrexate users for its effectiveness, alternative drugs and more.
What is Bladder discomfort?
Bladder discomfort is found to be associated with 464 drugs and 267 conditions by eHealthMe.
Number of Methotrexate and Bladder discomfort reports submitted per year:
Time on Methotrexate when people have Bladder discomfort *:
- < 1 month: 0.0 %
- 1 - 6 months: 100 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Bladder discomfort when taking Methotrexate *:
- female: 90 %
- male: 10 %
Age of people who have Bladder discomfort when taking Methotrexate *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 24 %
- 50-59: 24 %
- 60+: 52 %
Common drugs people take besides Methotrexate *:
- Humira: 7 people, 23.33%
- Cosentyx: 5 people, 16.67%
- Prednisone: 5 people, 16.67%
- Enbrel: 5 people, 16.67%
- Vitamin D: 5 people, 16.67%
- Carafate: 4 people, 13.33%
- Fosamax: 4 people, 13.33%
- Simponi: 4 people, 13.33%
- Neurontin: 3 people, 10.00%
- Prevacid: 3 people, 10.00%
Common side effects people have besides Bladder discomfort *:
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 12 people, 40.00%
- Micturition Urgency (urgency to pass the urine): 10 people, 33.33%
- Urination - Painful: 10 people, 33.33%
- Pain: 9 people, 30.00%
- Insomnia (sleeplessness): 8 people, 26.67%
- Fainting (loss of consciousness and postural tone): 7 people, 23.33%
- Flatulence (flatus expelled through the anus): 7 people, 23.33%
- Back Pain: 7 people, 23.33%
- Constipation: 6 people, 20.00%
- Fatigue (feeling of tiredness): 6 people, 20.00%
Common conditions people have *:
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 6 people, 20.00%
- Ankylosing Spondylitis (type of arthritis affecting the spine): 4 people, 13.33%
- Depression: 4 people, 13.33%
- Constipation: 3 people, 10.00%
- Pain: 2 people, 6.67%
- Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 2 people, 6.67%
- Psoriasis (immune-mediated disease that affects the skin): 2 people, 6.67%
- Gastritis (inflammation of stomach): 2 people, 6.67%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 6.67%
- Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough): 1 person, 3.33%
* Approximation only. Some reports may have incomplete information.
Do you take Methotrexate and have Bladder discomfort?Check whether Bladder discomfort is associated with a drug or a condition
How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Henien M, Carey B, Hullah E, Sproat C, Patel V, "methotrexate-associated osteonecrosis of the jaw: A report of two cases", Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2017 Dec .
How severe was Bladder discomfort and when was it recovered:
Expand to all the drugs that have ingredients of methotrexate sodium:
Alternative drugs to, pros and cons of Methotrexate:
- Methotrexate (475,317 reports)
Common Methotrexate side effects:
Browse all side effects of Methotrexate:a b c d e f g h i j k l m n o p q r s t u v w x y z
Bladder discomfort treatments and more:
- Bladder discomfort (1,345 reports)
COVID vaccines that are related to Bladder discomfort:
- Bladder discomfort in Moderna COVID Vaccine
- Bladder discomfort in Pfizer BioNTech Covid Vaccine
- Bladder discomfort in Johnson and Johnson Covid Vaccine
All the drugs that are associated with Bladder discomfort:
- Bladder discomfort (464 drugs)
All the conditions that are associated with Bladder discomfort:
- Bladder discomfort (267 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on methotrexate sodium (the active ingredients of Methotrexate) and Methotrexate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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