Methotrexate and Pml - from FDA reports
Pml is found among people who take Methotrexate, especially for people who are female, 60+ old , have been taking the drug for 5 - 10 years, also take medication Prednisone, and have Tonsil cancer. This review analyzes which people have Pml with Methotrexate. It is created by eHealthMe based on reports of 231,270 people who have side effects when taking Methotrexate from FDA , and is updated regularly.
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On Oct, 22, 2017
231,270 people reported to have side effects when taking Methotrexate.
Among them, 342 people (0.15%) have Pml
Number of reports submitted per year:
Time on Methotrexate when people have Pml *:
- < 1 month: 9.43 %
- 1 - 6 months: 22.64 %
- 6 - 12 months: 18.87 %
- 1 - 2 years: 1.89 %
- 2 - 5 years: 13.21 %
- 5 - 10 years: 30.19 %
- 10+ years: 3.77 %
Gender of people who have Pml when taking Methotrexate *:
- female: 65.87 %
- male: 34.13 %
Age of people who have Pml when taking Methotrexate *:
- 0-1: 0.0 %
- 2-9: 0.67 %
- 10-19: 6.71 %
- 20-29: 2.35 %
- 30-39: 6.38 %
- 40-49: 18.12 %
- 50-59: 21.81 %
- 60+: 43.96 %
Top conditions involved for these people *:
- Tonsil Cancer (22 people, 6.43%)
- Systemic Lupus Erythematosus (21 people, 6.14%)
- Polymyositis (15 people, 4.39%)
- Dermatomyositis (15 people, 4.39%)
- Acute Lymphocytic Leukemia (all) (14 people, 4.09%)
Top co-used drugs for these people *:
- Prednisone (62 people, 18.13%)
- Folic Acid (53 people, 15.50%)
- Cyclophosphamide (50 people, 14.62%)
- Rituxan (43 people, 12.57%)
- Prednisolone (42 people, 12.28%)
Top other side effects for these people *:
- Jc Virus Infection (39 people, 11.40%)
- Speech Impairment (adult) (32 people, 9.36%)
- Pneumonia (23 people, 6.73%)
- Weakness (19 people, 5.56%)
- Drug Ineffective (18 people, 5.26%)
* Approximation only. Some reports may have incomplete information.
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Do you have Pml when taking Methotrexate?
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Expand the study to include all drugs with the same ingredientsPml and drugs with ingredients of methotrexate sodium.
Expand the study to include reports from both FDA and eHealthMePml and Methotrexate from FDA and eHealthMe reports
Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 234,881 users)
Pml has been reported by people with multiple sclerosis, relapsing-remitting multiple sclerosis, chronic lymphocytic leukaemia, non-hodgkin's lymphoma, rheumatoid arthritis (latest reports from 7,860 Pml patients).
Browse all side effects of Methotrexatea b c d e f g h i j k l m n o p q r s t u v w x y z
Drugs that are associated with PmlPml
Could your condition cause PmlPml
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Questions to the study
Hi, I started on methotrexate approx 2mths ago to help with my rheumatoid condition Ankylosing Spondylitis. I also take Sulphasalazine and pre gabalin and have done since diagnosis 2.5yrs ago. Since starting in the methotrexate I have started to suffer with some unpleasant symptoms around ...
I started a low dose (10 mg) of methotrexate for rheumatoid arthritis last week and noticed this week, after taking my second does, that my face is breaking out. Does anyone have any similar experiences? I also take 5 mg of folic acid daily. Thanks for any help you can offer up.
Not sure what where to go with this. I have fibromyalgia and relapsing polchondritus also a disability from va.. I have my flares mostly under control. As well as what to do when they become apparent. After many years on pharmaceuticals I went a different direction. With medical marijauna. ...
Hi there, My names Adele I am 41 and have RA. I had my Gall Bladder removed in March of this year due to stones and constant infections. 2 years ago I stopped taking MTX subcutaneous and unfortunately my RA has progressed to a point I have (today) re-started these. I have headache, nausea and ...
Several years ago in 2013 I was"diagnosed" with RA. I went through every medication including, humira, embral, to now IV fusions of remicade which has been almost a year. I am not feeling any better and body aches and joint pains getting worse. I started researching my symptoms and lyme kept ...
User reviews to the study
It's been years since I've taken Methotrexate and when I was taking it years ago I had the numbness in my feet. Years later, it has returned and they're not sure what is the reason for my neuropathy. This time it's also in my hands. I took it for arthritis but now the military and the VA are ...
Hi everyone. I've been on methotrexate for about 10 years for psoriatic arthritis. My friends and family think it's funny how I'm always sweaty and hot when everyone else is comfortable or even cold. I, however, do not find it so funny that while sitting at a restaurant I start literally ...
Hi there, I have advanced RH, no medications for over past 12 years. Had an extreme flare up a few months back so went to rheumatologist who has prescribed 10 mg methotrexate, weekly and daily palquil, 5mg prednisone and 2x weekly folic acid. I have been on them nearly 3 months now. This ...