Methotrexate and Restless leg syndrome - a phase IV clinical study of FDA data
Restless leg syndrome is found among people who take Methotrexate, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years.
The phase IV clinical study analyzes which people take Methotrexate and have Restless leg syndrome. It is created by eHealthMe based on reports of 471,063 people who have side effects when taking Methotrexate from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.
471,063 people reported to have side effects when taking Methotrexate.
Among them, 384 people (0.08%) have Restless leg syndrome.
What is Methotrexate?
Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. eHealthMe is studying from 475,317 Methotrexate users for its effectiveness, alternative drugs and more.
What is Restless leg syndrome?
Restless leg syndrome (a powerful urge to move your legs) is found to be associated with 2,300 drugs and 1,735 conditions by eHealthMe.
Number of Methotrexate and Restless leg syndrome reports submitted per year:
Time on Methotrexate when people have Restless leg syndrome *:
Gender of people who have Restless leg syndrome when taking Methotrexate*:
Age of people who have Restless leg syndrome when taking Methotrexate *:
Common drugs people take besides Methotrexate *:
Common side effects people have besides Restless leg syndrome *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Methotrexate and have Restless leg syndrome?Check whether Restless leg syndrome is associated with a drug or a condition
How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Henien M, Carey B, Hullah E, Sproat C, Patel V, "methotrexate-associated osteonecrosis of the jaw: A report of two cases", Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2017 Dec .
Alternative drugs to, pros and cons of Methotrexate:
- Methotrexate (475,317 reports)
Restless leg syndrome treatments and more:
- Restless leg syndrome (41,962 reports)
COVID vaccines that are related to Restless leg syndrome:
- Restless leg syndrome in Moderna COVID Vaccine
- Restless leg syndrome in Pfizer BioNTech Covid Vaccine
- Restless leg syndrome in Johnson and Johnson Covid Vaccine
How severe was Restless leg syndrome and when was it recovered:
Expand to all the drugs that have ingredients of methotrexate sodium:
Common drugs associated with Restless leg syndrome:
All the drugs that are associated with Restless leg syndrome:
- Restless leg syndrome (2,300 drugs)
Common conditions associated with Restless leg syndrome:
All the conditions that are associated with Restless leg syndrome:
- Restless leg syndrome (1,735 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on methotrexate sodium (the active ingredients of Methotrexate) and Methotrexate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.