Methyldopa and Blood bilirubin increased - a phase IV clinical study of FDA data
Summary:
Blood bilirubin increased is found among people who take Methyldopa, especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months.
The phase IV clinical study analyzes which people take Methyldopa and have Blood bilirubin increased. It is created by eHealthMe based on reports of 5,610 people who have side effects when taking Methyldopa from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
5,610 people reported to have side effects when taking Methyldopa.
Among them, 17 people (0.3%) have Blood bilirubin increased.
What is Methyldopa?
Methyldopa has active ingredients of methyldopa. It is often used in high blood pressure. eHealthMe is studying from 5,740 Methyldopa users for its effectiveness, alternative drugs and more.
What is Blood bilirubin increased?
Blood bilirubin increased is found to be associated with 2,566 drugs and 2,147 conditions by eHealthMe.
Number of Methyldopa and Blood bilirubin increased reports submitted per year:

Time on Methyldopa when people have Blood bilirubin increased *:
- < 1 month: 0.0 %
- 1 - 6 months: 100 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Blood bilirubin increased when taking Methyldopa *:
- female: 41.18 %
- male: 58.82 %
Age of people who have Blood bilirubin increased when taking Methyldopa *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 7.14 %
- 20-29: 0.0 %
- 30-39: 7.14 %
- 40-49: 7.14 %
- 50-59: 14.29 %
- 60+: 64.29 %
Common drugs people take besides Methyldopa *:
- Amlodipine: 5 people, 29.41%
- Xarelto: 4 people, 23.53%
- Oxycodone: 4 people, 23.53%
- Sandostatin: 3 people, 17.65%
- Hydrochlorothiazide: 3 people, 17.65%
- Micardis: 2 people, 11.76%
- Aspirin: 2 people, 11.76%
- Januvia: 2 people, 11.76%
- Vitamins: 2 people, 11.76%
- Lyrica: 2 people, 11.76%
Common side effects people have besides Blood bilirubin increased *:
- Aspartate Aminotransferase Increased: 10 people, 58.82%
- Alanine Aminotransferase Increased: 10 people, 58.82%
- Blood Alkaline Phosphatase Increased: 7 people, 41.18%
- Gamma-Glutamyltransferase Increased: 5 people, 29.41%
- 5-Hydroxyindolacetic Acid In Urine Increased (increased serotonin levels): 4 people, 23.53%
- Blood Glucose Increased: 4 people, 23.53%
- Malignant Neoplasm Progression (cancer tumour came back): 4 people, 23.53%
- Constipation: 4 people, 23.53%
- Laryngospasm (an uncontrolled/involuntary muscular contraction of larynx): 4 people, 23.53%
- Laryngeal Oedema (swelling of larynx): 4 people, 23.53%
Common conditions people have *:
- Pain: 5 people, 29.41%
- Prostatic Specific Antigen Increased: 4 people, 23.53%
- Neuroendocrine Tumor: 4 people, 23.53%
- Enlarged Prostate: 4 people, 23.53%
- Breathing Difficulty: 4 people, 23.53%
- Neuromuscular Blockade Reversal: 1 person, 5.88%
- Neuromuscular Blockade: 1 person, 5.88%
- Heart Attack: 1 person, 5.88%
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 5.88%
- Eclampsia (acute and life-threatening complication of pregnancy): 1 person, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Methyldopa and have Blood bilirubin increased?
Check whether Blood bilirubin increased is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Blood bilirubin increased and when was it recovered:
Expand to all the drugs that have ingredients of methyldopa:
Alternative drugs to, pros and cons of Methyldopa:
- Methyldopa (5,740 reports)
Common Methyldopa side effects:
- High blood pressure: 513 reports
- Breathing difficulty: 269 reports
- Drug ineffective: 242 reports
Browse all side effects of Methyldopa:
a b c d e f g h i j k l m n o p q r s t u v w x y zBlood bilirubin increased treatments and more:
- Blood bilirubin increased (40,401 reports)
COVID vaccines that are related to Blood bilirubin increased:
- Blood bilirubin increased in Moderna COVID Vaccine
- Blood bilirubin increased in Pfizer BioNTech Covid Vaccine
- Blood bilirubin increased in Johnson and Johnson Covid Vaccine
Common drugs associated with Blood bilirubin increased:
- Lasix: 1,572 reports
- Furosemide: 1,541 reports
- Prednisone: 1,473 reports
- Aspirin: 1,334 reports
- Omeprazole: 1,325 reports
- Methotrexate: 1,209 reports
- Ribavirin: 1,143 reports
- Tracleer: 1,057 reports
- Allopurinol: 1,020 reports
- Lopurin: 1,020 reports
All the drugs that are associated with Blood bilirubin increased:
- Blood bilirubin increased (2,566 drugs)
Common conditions associated with Blood bilirubin increased:
- High blood pressure: 1,674 reports
- Hepatitis c: 1,077 reports
- Hiv infection: 1,030 reports
- Primary pulmonary hypertension: 815 reports
- Pain: 814 reports
- Multiple sclerosis: 780 reports
- Preventive health care: 778 reports
All the conditions that are associated with Blood bilirubin increased:
- Blood bilirubin increased (2,147 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on methyldopa (the active ingredients of Methyldopa) and Methyldopa (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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