Methylprednisolone sodium succinate and Epstein-barr virus infection - a phase IV clinical study of FDA data

Summary:

Epstein-barr virus infection is found among people who take Methylprednisolone sodium succinate, especially for people who are male, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Methylprednisolone sodium succinate and have Epstein-barr virus infection. It is created by eHealthMe based on reports of 13,080 people who have side effects when taking Methylprednisolone sodium succinate from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Mar, 26, 2023

13,080 people reported to have side effects when taking Methylprednisolone sodium succinate.
Among them, 68 people (0.52%) have Epstein-barr virus infection.


What is Methylprednisolone sodium succinate?

Methylprednisolone sodium succinate has active ingredients of methylprednisolone sodium succinate. eHealthMe is studying from 13,090 Methylprednisolone sodium succinate users for its effectiveness, alternative drugs and more.

What is Epstein-barr virus infection?

Epstein-barr virus infection is found to be associated with 1,006 drugs and 680 conditions by eHealthMe.

Number of Methylprednisolone sodium succinate and Epstein-barr virus infection reports submitted per year:

Could Methylprednisolone sodium succinate cause Epstein-barr virus infection?

Time on Methylprednisolone sodium succinate when people have Epstein-barr virus infection *:

  • < 1 month: 86.67 %
  • 1 - 6 months: 13.33 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Epstein-barr virus infection when taking Methylprednisolone sodium succinate *:

  • female: 43.08 %
  • male: 56.92 %

Age of people who have Epstein-barr virus infection when taking Methylprednisolone sodium succinate *:

  • 0-1: 17.24 %
  • 2-9: 20.69 %
  • 10-19: 15.52 %
  • 20-29: 1.72 %
  • 30-39: 1.72 %
  • 40-49: 0.0 %
  • 50-59: 20.69 %
  • 60+: 22.41 %

Common drugs people take besides Methylprednisolone sodium succinate *:

  1. Methotrexate: 19 people, 27.94%
  2. Micafungin Sodium: 18 people, 26.47%
  3. Fluconazole: 15 people, 22.06%
  4. Levofloxacin: 13 people, 19.12%
  5. Tacrolimus: 12 people, 17.65%
  6. Ursodeoxycholic Acid: 12 people, 17.65%
  7. Cyclosporine: 10 people, 14.71%
  8. Acyclovir: 10 people, 14.71%
  9. Ganciclovir: 10 people, 14.71%
  10. Fludara: 9 people, 13.24%

Common side effects people have besides Epstein-barr virus infection *:

  1. Fever: 30 people, 44.12%
  2. Diarrhea: 18 people, 26.47%
  3. Cytomegalovirus Infection: 15 people, 22.06%
  4. Febrile Neutropenia (fever with reduced white blood cells): 12 people, 17.65%
  5. Nausea (feeling of having an urge to vomit): 12 people, 17.65%
  6. Hepatic Function Abnormal: 11 people, 16.18%
  7. Thrombocytopenia (decrease of platelets in blood): 10 people, 14.71%
  8. Pleural Effusion (water on the lungs): 7 people, 10.29%
  9. Liver Disorder (liver diseases): 7 people, 10.29%
  10. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 6 people, 8.82%

Common conditions people have *:

  1. Bone Marrow Conditioning Regimen: 20 people, 29.41%
  2. Aplastic Anemia: 17 people, 25.00%
  3. Acute Graft Versus Host Disease (acute complication following an allogeneic tissue/blood transplant): 7 people, 10.29%
  4. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 7 people, 10.29%
  5. Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 6 people, 8.82%
  6. High Blood Pressure: 6 people, 8.82%
  7. Fever: 5 people, 7.35%
  8. Depression: 4 people, 5.88%
  9. Rickets (softening of bones): 4 people, 5.88%
  10. Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Methylprednisolone sodium succinate and have Epstein-barr virus infection?

Check whether Epstein-barr virus infection is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



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Epstein-barr virus infection treatments and more:

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All the drugs that are associated with Epstein-barr virus infection:

Common conditions associated with Epstein-barr virus infection:

All the conditions that are associated with Epstein-barr virus infection:

How the study uses the data?

The study uses data from the FDA. It is based on methylprednisolone sodium succinate (the active ingredients of Methylprednisolone sodium succinate) and Methylprednisolone sodium succinate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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