Metoprolol succinate and Restless leg syndrome - a phase IV clinical study of FDA data

• Metoprolol succinate (54,831 reports)

• Abdominal discomfort: 746 reports
• Abdominal distension: 451 reports
• Abdominal pain: 875 reports
• Abdominal pain upper: 794 reports
• Abnormal dreams: 109 reports
• Acute kidney failure: 1,279 reports
• Acute myocardial infarction (acute heart attack): 319 reports
• Acute respiratory failure: 163 reports
• Adverse drug reaction: 230 reports
• Adverse event: 223 reports
• Ageusia (loss of taste functions of the tongue): 126 reports
• Aggression: 121 reports
• Agitation (state of anxiety or nervous excitement): 358 reports
• Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 319 reports
• Alanine aminotransferase increased: 286 reports
• Anaemia (lack of blood): 1,115 reports
• Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 121 reports
• Angina unstable (chest pain due to ischemia of the heart muscle- unstable): 144 reports
• Angioedema (rapid swelling of the dermis): 147 reports
• Anhedonia (inability to experience pleasure from activities usually found enjoyable): 226 reports
• Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight): 113 reports
• Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta): 115 reports
• Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 1,189 reports
• Appetite - increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires): 132 reports
• Arrhythmias (irregular heartbeat): 902 reports
• Arthritis (form of joint disorder that involves inflammation of one or more joints): 404 reports
• Arthropathy: 210 reports
• Ascites (accumulation of fluid in the abdominal cavity): 164 reports
• Aspartate aminotransferase increased: 272 reports
• Asthma: 257 reports
• Atelectasis (partial or complete collapse of the lung): 132 reports
• Atherosclerosis (disorder of the arteries): 115 reports
• Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1,575 reports
• Back pain: 1,225 reports
• Balance disorder: 489 reports
• Belching (release of gas from the digestive tract): 103 reports
• Bleeding disorders: 119 reports
• Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 224 reports
• Blood alkaline phosphatase increased: 136 reports
• Blood bilirubin increased: 137 reports
• Blood calcium decreased: 114 reports
• Blood creatine phosphokinase increased: 156 reports
• Blood creatinine increased: 590 reports
• Blood glucose decreased: 199 reports
• Blood glucose increased: 758 reports
• Blood lactate dehydrogenase increased: 106 reports
• Blood potassium decreased: 252 reports
• Blood pressure fluctuation: 231 reports
• Blood pressure management: 360 reports
• Blood pressure systolic increased: 122 reports
• Blood sodium decreased: 172 reports
• Blood urea increased: 192 reports
• Blood urine present: 111 reports
• Body height decreased: 152 reports
• Bone disorder: 127 reports
• Bone pain: 253 reports
• Bradycardia (abnormally slow heart action): 591 reports
• Breast cancer: 118 reports
• Breathing difficulty: 3,093 reports
• Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 500 reports
• Burning sensation: 267 reports
• Cardiac arrest: 458 reports
• Cardiac disorder: 623 reports
• Cardiac failure: 649 reports
• Cardiac failure congestive: 851 reports
• Cardiac murmur (an heart sound in valve abnormality): 103 reports
• Cardiogenic shock (inadequate circulation of blood): 171 reports
• Cardiomyopathy (weakening of the heart muscle): 117 reports
• Cardio-respiratory arrest (sudden dysfunction of heart and lungs): 127 reports
• Cataract (clouding of the lens inside the eye): 293 reports
• Cellulitis (infection under the skin): 299 reports
• Cerebral haemorrhage (bleeding within the brain): 172 reports
• Cerebral infarction (less blood supply to brain resulting tissue damage): 111 reports
• Chest pain: 1,746 reports
• Chills (felling of cold): 474 reports
• Chronic kidney disease: 948 reports
• Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe): 401 reports
• Circulatory collapse: 134 reports
• Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving): 156 reports
• Completed suicide (act of taking one's own life): 224 reports
• Condition: 586 reports
• Confusion: 221 reports
• Confusional state: 696 reports
• Consciousness - decreased: 160 reports
• Constipation: 1,169 reports
• Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 207 reports
• Coronary artery occlusion (complete obstruction of blood flow in a coronary artery): 272 reports
• Coronary heart disease (narrowing or blockage of the coronary arteries): 441 reports
• Cough: 1,117 reports
• Coughing up blood: 201 reports
• C-reactive protein increased: 146 reports
• Death: 1,858 reports
• Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 344 reports
• Dehydration (dryness resulting from the removal of water): 1,003 reports
• Delirium (wild excitement): 145 reports
• Dementia (madness): 116 reports
• Depressed level of consciousness: 131 reports
• Depressed mood: 149 reports
• Depression: 1,001 reports
• Diabetes: 452 reports
• Diarrhea: 3,273 reports
• Diplopia (double vision): 113 reports
• Discomfort: 205 reports
• Disease progression: 297 reports
• Disturbance in attention: 169 reports
• Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 176 reports
• Dizziness: 2,794 reports
• Drowsiness: 843 reports
• Drug effect decreased: 149 reports
• Drug hypersensitivity: 442 reports
• Drug ineffective: 2,328 reports
• Drug intolerance (drug sensitivity): 245 reports
• Dry eyes (lack of adequate tears): 141 reports
• Dry mouth: 387 reports
• Dry skin: 323 reports
• Dyskinesia (abnormality or impairment of voluntary movement): 134 reports
• Dyspnea exertional: 352 reports
• Ear pain: 102 reports
• Ejection fraction decreased (systolic heart failure): 168 reports
• Electrocardiogram qt prolonged: 183 reports
• Emotional distress: 331 reports
• Encephalopathy (functioning of the brain is affected by some agent or condition): 132 reports
• Enlarged heart: 148 reports
• Erection problems: 123 reports
• Erythema multiforme (a type of hypersensitivity reaction): 124 reports
• Eye pain: 165 reports
• Eye swelling: 111 reports
• Faeces discolored: 115 reports
• Fainting (loss of consciousness and postural tone): 797 reports
• Fall: 1,971 reports
• Fatigue (feeling of tiredness): 4,114 reports
• Fear: 186 reports
• Febrile neutropenia (fever with reduced white blood cells): 178 reports
• Feeling cold: 135 reports
• Feeling hot: 195 reports
• Femur fracture: 112 reports
• Fever: 1,118 reports
• Fibromyalgia (a long-term condition which causes pain all over the body): 109 reports
• Flatulence (flatus expelled through the anus): 285 reports
• Fluid overload (too much fluid in the blood): 117 reports
• Fluid retention (an abnormal accumulation of fluid in the blood): 341 reports
• Foot fracture: 102 reports
• Full blood count decreased: 173 reports
• Fungal infection: 131 reports
• Gait disturbance: 952 reports
• Gallstones (stone formation by bile component): 238 reports
• Gamma-glutamyltransferase increased: 105 reports
• Gastric disorder (disease of stomach): 148 reports
• Gastric ulcer (stomach ulcer): 284 reports
• Gastritis (inflammation of stomach): 182 reports
• Gastroenteritis (inflammation of stomach and intestine): 112 reports
• Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 571 reports
• Gastrointestinal disorder (functional problems of gastrointestinal tract): 268 reports
• Gastrointestinal haemorrhage (bleeding gastrointestinal tract): 772 reports
• General physical health deterioration (weak health status): 431 reports
• Gout (uric acid crystals building up in the body): 226 reports
• Haematemesis (vomiting of blood): 111 reports
• Haematochezia (passage of stools containing blood): 212 reports
• Haematocrit decreased: 242 reports
• Haematoma (collection of blood outside the blood vessels): 187 reports
• Haematuria (presence of blood in urine): 264 reports
• Haemoglobin decreased: 804 reports
• Haemorrhage (bleeding): 417 reports
• Haemorrhoids (a swollen vein or group of veins in the region of the anus): 135 reports
• Hair loss: 644 reports
• Hallucinations (sensations that appear real but are created by your mind): 352 reports
• Headache (pain in head): 2,114 reports
• Head injury: 872 reports
• Hearing loss: 103 reports
• Heart attack: 1,347 reports
• Heart disease: 128 reports
• Heart palpitations (feelings or sensations that your heart is pounding or racing): 800 reports
• Heart rate decreased: 299 reports
• Heart rate increased: 762 reports
• Heart rate irregular: 384 reports
• Hepatic enzyme increased: 238 reports
• Hepatic failure (liver failure): 120 reports
• Hepatic steatosis (fatty liver disease): 137 reports
• Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle): 101 reports
• Herpes zoster: 267 reports
• Hiatal hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 185 reports
• High blood cholesterol: 577 reports
• High blood pressure: 2,830 reports
• Hip fracture: 188 reports
• Hoarseness or changing voice: 246 reports
• Hospitalisation: 344 reports
• Hot flush (sudden feelings of heat): 258 reports
• Hyperglycemia (high blood sugar): 184 reports
• Hyperhidrosis (abnormally increased sweating): 547 reports
• Hyperkalemia (damage to or disease of the kidney): 478 reports
• Hyperlipidaemia (presence of excess lipids in the blood): 158 reports
• Hypersensitivity: 480 reports
• Hypertensive crisis: 120 reports
• Hypoacusis (loss of hearing): 178 reports
• Hypoaesthesia (reduced sense of touch or sensation): 673 reports
• Hypocalcaemia (levels of calcium in blood serum are abnormally low): 106 reports
• Hypoglycemia (low blood sugar): 191 reports
• Hypokalemia (low potassium): 390 reports
• Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 126 reports
• Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 327 reports
• Hypophagia (reduced food intake): 140 reports
• Hypotension (abnormally low blood pressure): 1,885 reports
• Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 171 reports
• Ill-defined disorder: 160 reports
• Impaired healing: 207 reports
• Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone): 112 reports
• Indigestion: 521 reports
• Infection: 472 reports
• Inflammation: 152 reports
• Influenza like illness: 247 reports
• Injection site erythema (redness at injection site): 148 reports
• Injection site haemorrhage (bleeding from injection site): 120 reports
• Injection site pain: 296 reports
• Injury: 382 reports
• Insomnia (sleeplessness): 1,176 reports
• International normalised ratio increased: 312 reports
• Interstitial nephritis (inflammation of the kidney): 149 reports
• Intervertebral disc degeneration (spinal disc degeneration): 128 reports
• Intervertebral disc protrusion (spinal disc protrusion): 138 reports
• Intestinal obstruction: 155 reports
• Irritability: 111 reports
• Irritable bowel syndrome: 102 reports
• Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain): 101 reports
• Itching: 1,129 reports
• Joint pain: 1,382 reports
• Joint swelling: 410 reports
• Kidney stones: 226 reports
• Lactic acidosis (low ph in body tissues): 148 reports
• Leukocytosis (increased white blood cells): 163 reports
• Leukopenia (less number of white blood cells in blood): 198 reports
• Limb discomfort (discomfort in leg): 148 reports
• Limb injury: 144 reports
• Liver disorder (liver diseases): 118 reports
• Localised infection (infection at the single location): 111 reports
• Loss of consciousness: 567 reports
• Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding): 117 reports
• Low tissue oxygen: 144 reports
• Lung disorder (lung disease): 180 reports
• Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung): 110 reports
• Lymph follicular hypertrophy (an increase in the size of the lymph node follicles): 133 reports
• Malaise (a feeling of general discomfort or uneasiness): 1,522 reports
• Malignant neoplasm progression (cancer tumour came back): 236 reports
• Melaena (the passage of black, tarry stools): 158 reports
• Memory loss: 893 reports
• Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 123 reports
• Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition): 114 reports
• Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 235 reports
• Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 155 reports
• Metastases to bone (cancer spreads to bone): 117 reports
• Migraine (headache): 231 reports
• Mitral valve incompetence (inefficient heart valve): 184 reports
• Mobility decreased (ability to move is reduced): 232 reports
• Mood swings (an extreme or rapid change in mood): 113 reports
• Multi-organ failure (multisystem organ failure): 173 reports
• Multiple myeloma (cancer of the plasma cells): 186 reports
• Muscle aches (muscle pain): 724 reports
• Muscle spasms (muscle contraction): 788 reports
• Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves): 105 reports
• Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 291 reports
• Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 270 reports
• Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 182 reports
• Nasopharyngitis (inflammation of the nasopharynx): 536 reports
• Nausea (feeling of having an urge to vomit): 3,259 reports
• Nausea and vomiting: 1,772 reports
• Neck pain: 241 reports
• Neoplasm malignant (cancer tumour): 158 reports
• Neoplasm progression (growth of tumour): 131 reports
• Nephrogenic anaemia (anaemia due to kidney disease): 206 reports
• Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease): 126 reports
• Nervousness: 224 reports
• Neuropathy peripheral (surface nerve damage): 541 reports
• Nightmares (unpleasant dreams): 125 reports
• Night sweats (sweating in night): 171 reports
• Nosebleed (bleeding from nose): 505 reports
• Oedema (fluid collection in tissue): 310 reports
• Oedema peripheral (superficial swelling): 980 reports
• Oropharyngeal pain: 260 reports
• Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 153 reports
• Osteoarthritis (a joint disease caused by cartilage loss in a joint): 258 reports
• Osteomyelitis (infection of bone): 123 reports
• Osteonecrosis of jaw (death of bone of jaw): 165 reports
• Osteopenia (a condition where bone mineral density is lower than normal): 130 reports
• Osteoporosis (bones weak and more likely to break): 218 reports
• Overdose: 344 reports
• Oxygen saturation decreased: 227 reports
• Pain: 2,207 reports
• Pain in extremity: 1,238 reports
• Pain in jaw: 120 reports
• Pancreatitis (inflammation of pancreas): 181 reports
• Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 259 reports
• Panic disorder: 116 reports
• Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 481 reports
• Parkinson's disease: 127 reports
• Paroxysmal supraventricular tachycardia: 119 reports
• Pericardial effusion (fluid around the heart): 157 reports
• Peripheral coldness: 111 reports
• Peripheral swelling: 742 reports
• Pleural effusion (water on the lungs): 486 reports
• Pneumonia: 1,872 reports
• Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 105 reports
• Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 216 reports
• Poor quality sleep: 114 reports
• Pre-existing condition improved: 123 reports
• Presyncope: 143 reports
• Productive cough: 224 reports
• Prostatic specific antigen increased: 105 reports
• Pruritus generalised (generalized itching): 101 reports
• Psoriasis (immune-mediated disease that affects the skin): 240 reports
• Pulmonary congestion (congestion in the lungs): 124 reports
• Pulmonary embolism (blockage of the main artery of the lung): 403 reports
• Pulmonary hypertension (increase in blood pressure in the lung artery): 222 reports
• Pulmonary oedema (fluid accumulation in the lungs): 353 reports
• Rash erythematous (redness of the skin): 104 reports
• Rashes (redness): 1,928 reports
• Rash macular (small, flat red spots): 113 reports
• Rash pruritic (redness with itching): 192 reports
• Rectal haemorrhage (bleeding from anus): 247 reports
• Red blood cell count decreased: 242 reports
• Renal disorder (kidney disease): 239 reports
• Renal failure acute (rapid kidney dysfunction): 579 reports
• Renal failure chronic (long lasting kidney dysfunction): 155 reports
• Renal impairment (severely reduced kidney function): 477 reports
• Renal injury (kidney injury): 320 reports
• Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 416 reports
• Respiratory distress (difficulty in breathing): 111 reports
• Respiratory tract infection: 109 reports
• Restless leg syndrome (a powerful urge to move your legs): 102 reports
• Retching (strong involuntary effort to vomit): 117 reports
• Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 298 reports
• Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints): 196 reports
• Rib fracture: 154 reports
• Road traffic accident: 136 reports
• Seizures (abnormal excessive or synchronous neuronal activity in the brain): 240 reports
• Sepsis (a severe blood infection that can lead to organ failure and death): 630 reports
• Septic shock (shock due to blood infection): 145 reports
• Sinus bradycardia (an unusually slow heartbeat due to heart disease): 160 reports
• Sinus disorder (disease of sinus): 111 reports
• Sinusitis (inflammation of sinus): 556 reports
• Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 126 reports
• Skin blushing/flushing (a sudden reddening of the face, neck): 404 reports
• Skin - clammy: 102 reports
• Skin discoloration: 265 reports
• Skin disorder (skin disease): 112 reports
• Skin exfoliation (removal of the oldest dead skin cells): 228 reports
• Skin ulcer: 172 reports
• Sleep apnea syndrome: 208 reports
• Sleep disorder: 273 reports
• Speech disorder: 239 reports
• Speech impairment (adult) (inability to speak (adult)): 333 reports
• Spinal fracture (fracture in one of vertebrae): 107 reports
• Spinal osteoarthritis (joint cartilage loss in spine): 126 reports
• Splenomegaly (enlargement of spleen): 102 reports
• Stable angina (a constant chest pain): 336 reports
• Staphylococcal infection (an infection with staphylococcus bacteria): 212 reports
• Stent: 119 reports
• Stomatitis (inflammation of mucous membrane of mouth): 294 reports
• Stress and anxiety: 1,422 reports
• Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 855 reports
• Suicidal ideation: 171 reports
• Suicide attempt: 142 reports
• Surgery: 180 reports
• Swallowing difficulty: 469 reports
• Swelling: 338 reports
• Swelling face: 188 reports
• Swollen tongue (swelling of tongue): 132 reports
• Taste - impaired: 316 reports
• The flu (the flu is caused by an influenza virus): 413 reports
• Therapeutic response decreased (less preventive response): 122 reports
• Therapeutic response unexpected: 200 reports
• Throat irritation: 117 reports
• Thrombocytopenia (decrease of platelets in blood): 1,032 reports
• Thrombosis (formation of a blood clot inside a blood vessel): 427 reports
• Thyroid diseases: 104 reports
• Tinnitus (a ringing in the ears): 186 reports
• Tooth abscess (pus formation in tooth): 132 reports
• Tooth disorder (tooth disease): 129 reports
• Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 297 reports
• Tremor (trembling or shaking movements in one or more parts of your body): 624 reports
• Tricuspid valve incompetence (inefficient heart valve): 129 reports
• Type 2 diabetes: 211 reports
• Unresponsive to stimuli: 148 reports
• Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding): 128 reports
• Upper respiratory tract infection: 239 reports
• Urinary incontinence (inability to control the flow of urine and involuntary urination): 179 reports
• Urinary retention (the inability to completely or partially empty the bladder): 188 reports
• Urinary tract infection: 1,243 reports
• Urination - painful: 208 reports
• Urticaria (rash of round, red welts on the skin that itch intensely): 410 reports
• Ventricular extrasystoles (premature cardiac contraction): 182 reports
• Ventricular fibrillation (abnormally irregular heart rhythm): 136 reports
• Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 186 reports
• Viral infection: 138 reports
• Vision blurred: 533 reports
• Visual acuity reduced (reduced clearness of vision): 120 reports
• Visual impairment: 383 reports
• Weakness: 2,607 reports
• Weight decreased: 1,476 reports
• Weight increased: 895 reports
• Weight loss: 150 reports
• Wheezing (a high-pitched whistling sound made while you breath): 192 reports
• White blood cell count decreased: 513 reports
• White blood cell count increased: 227 reports

• Restless leg syndrome (44,924 reports)

• Abilify: 454 reports
• Acetaminophen: 214 reports
• Acetylsalicylic acid: 229 reports
• Aciphex: 106 reports
• Actemra: 142 reports
• Actonel: 106 reports
• Adderall: 288 reports
• Advair diskus 100/50: 132 reports
• Advair hfa: 117 reports
• Advil: 126 reports
• Albuterol: 364 reports
• Albuterol sulfate: 131 reports
• Alendronate sodium: 277 reports
• Aleve: 114 reports
• Allegra: 186 reports
• Allopurinol: 212 reports
• Alprazolam: 236 reports
• Ambien: 487 reports
• Amlodipine: 352 reports
• Amlodipine besylate: 105 reports
• Amoxicillin: 169 reports
• Ampyra: 155 reports
• Aredia: 183 reports
• Aripiprazole: 157 reports
• Aspirin: 988 reports
• Atenolol: 291 reports
• Ativan: 332 reports
• Atrovent: 134 reports
• Aubagio: 107 reports
• Avonex: 269 reports
• Baclofen: 270 reports
• Benadryl: 327 reports
• Calcium: 311 reports
• Carvedilol: 175 reports
• Celebrex: 357 reports
• Celexa: 220 reports
• Chantix: 184 reports
• Citalopram hydrobromide: 108 reports
• Claritin: 181 reports
• Clonazepam: 760 reports
• Clonidine: 129 reports
• Clopra: 852 reports
• Codeine: 153 reports
• Colace: 165 reports
• Coumadin: 360 reports
• Cozaar: 122 reports
• Crestor: 343 reports
• Crysvita: 243 reports
• Cymbalta: 782 reports
• Decadron: 101 reports
• Depakote: 172 reports
• Dexamethasone: 109 reports
• Diazepam: 372 reports
• Digoxin: 102 reports
• Dilaudid: 112 reports
• Diovan: 172 reports
• Diphen: 206 reports
• Doxycycline: 145 reports
• Duragesic: 152 reports
• Duragesic-100: 104 reports
• Effexor: 502 reports
• Effexor xr: 156 reports
• Elavil: 111 reports
• Eliquis: 127 reports
• Enbrel: 314 reports
• Escitalopram: 220 reports
• Ezetimibe: 106 reports
• Famotidine: 102 reports
• Fentanyl: 183 reports
• Fish oil: 267 reports
• Flexeril: 199 reports
• Flomax: 118 reports
• Flonase: 232 reports
• Fluoxetine: 391 reports
• Folic acid: 193 reports
• Forteo: 219 reports
• Fosamax: 892 reports
• Furosemide: 492 reports
• Gabapentin: 979 reports
• Geodon: 116 reports
• Gilenya: 273 reports
• Humalog: 131 reports
• Humira: 453 reports
• Hydramine: 206 reports
• Hydrochlorothiazide: 422 reports
• Hydrocodone bitartrate and acetaminophen: 126 reports
• Hydroxyzine: 110 reports
• Ibu: 470 reports
• Ibuprofen: 468 reports
• Ingrezza: 104 reports
• Klonopin: 393 reports
• Klor-con: 108 reports
• Lamictal: 225 reports
• Lamotrigine: 181 reports
• Lansoprazole: 146 reports
• Lantus: 178 reports
• Lasix: 465 reports
• Latuda: 172 reports
• Levaquin: 168 reports
• Levothyroxine sodium: 222 reports
• Lexapro: 407 reports
• Lipitor: 585 reports
• Lisinopril: 609 reports
• Lopurin: 212 reports
• Loratadine: 143 reports
• Loraz: 518 reports
• Lorazepam: 518 reports
• Lortab: 199 reports
• Losartan: 219 reports
• Lunesta: 108 reports
• Lyrica: 870 reports
• Magnesium: 321 reports
• Melatonin: 248 reports
• Meloxicam: 172 reports
• Metformin: 566 reports
• Methotrexate: 440 reports
• Metoclopramide: 850 reports
• Metoclopramide hydrochloride: 178 reports
• Metoprolol succinate: 102 reports
• Metoprolol tartrate: 160 reports
• Miralax: 133 reports
• Mirapex: 510 reports
• Mirtazapine: 628 reports
• Modafinil: 160 reports
• Morphine: 331 reports
• Motrin: 108 reports
• Multivitamin: 181 reports
• Naproxen: 114 reports
• Nasonex: 115 reports
• Neupro: 241 reports
• Neurontin: 492 reports
• Nexium: 470 reports
• Norco: 158 reports
• Norvasc: 233 reports
• Nuvigil: 176 reports
• Nystatin: 101 reports
• Olanzapine: 162 reports
• Omeprazole: 848 reports
• Ondansetron: 159 reports
• Opsumit: 130 reports
• Oxycodone: 303 reports
• Oxycontin: 320 reports
• Pantoprazole: 408 reports
• Paracetamol: 138 reports
• Paroxetine: 278 reports
• Paxil: 273 reports
• Pepcid: 141 reports
• Percocet: 320 reports
• Phenergan: 129 reports
• Plaquenil: 153 reports
• Plavix: 217 reports
• Potassium: 127 reports
• Prednisolone: 108 reports
• Prednisone: 653 reports
• Pregabalin: 156 reports
• Premarin: 207 reports
• Prevacid: 214 reports
• Prilosec: 402 reports
• Proair hfa: 111 reports
• Profen: 468 reports
• Promethazine: 118 reports
• Protonix: 278 reports
• Provigil: 144 reports
• Prozac: 347 reports
• Pulmicort: 143 reports
• Quetiapine fumarate: 174 reports
• Ramipril: 190 reports
• Ranitidine: 193 reports
• Reglan: 362 reports
• Remicade: 118 reports
• Requip: 829 reports
• Restoril: 102 reports
• Revlimid: 195 reports
• Risperdal: 220 reports
• Risperidone: 106 reports
• Ritalin: 136 reports
• Rituxan: 101 reports
• Saphris: 109 reports
• Seroquel: 709 reports
• Sertraline: 479 reports
• Simvastatin: 378 reports
• Sinemet: 180 reports
• Singulair: 327 reports
• Spiriva: 246 reports
• Spironolactone: 199 reports
• Suboxone: 119 reports
• Symbicort: 173 reports
• Synthroid: 602 reports
• Tamsulosin: 107 reports
• Tecfidera: 122 reports
• Temaz: 164 reports
• Temazepam: 164 reports
• Topamax: 191 reports
• Topiramate: 126 reports
• Toprol-xl: 115 reports
• Tramadol: 670 reports
• Tramadol hydrochloride: 106 reports
• Tylenol: 459 reports
• Tysabri: 200 reports
• Ultram: 129 reports
• Valium: 203 reports
• Vicodin: 259 reports
• Vioxx: 314 reports
• Vitamin b12: 321 reports
• Vitamin c: 212 reports
• Vitamin d: 590 reports
• Vitamin d3: 307 reports
• Vitamins: 271 reports
• Vivitrol: 122 reports
• Wellbutrin: 427 reports
• Xanax: 499 reports
• Xeljanz: 123 reports
• Xtandi: 206 reports
• Xyrem: 831 reports
• Zantac: 210 reports
• Zetia: 124 reports
• Zide: 423 reports
• Zocor: 242 reports
• Zofran: 248 reports
• Zoloft: 454 reports
• Zolpidem: 254 reports
• Zometa: 271 reports
• Zopiclone: 214 reports
• Zyprexa: 160 reports
• Zyrtec: 257 reports

All the drugs that are associated with Restless leg syndrome:

• Restless leg syndrome (2,376 drugs)

• Acid reflux: 450 reports
• Acupuncture and pain: 549 reports
• Adhd: 101 reports
• Adult hypothyroidism: 246 reports
• Agrypnia: 485 reports
• Alternative medicine - pain relief: 976 reports
• Antidepressant therapy: 1,613 reports
• Anxiety: 767 reports
• Anxiety aggravated: 767 reports
• Anxiety and stress: 767 reports
• Anxiety, apprehension, feeling uptight, jitters, stress, stress and anxiety, tension: 767 reports
• Anxiolytic therapy: 767 reports
• Apprehension: 767 reports
• Arthritis: 232 reports
• Arthritis - rheumatoid: 741 reports
• Asthma: 342 reports
• Back pain: 283 reports
• Back pain - nonspecific: 283 reports
• Bipolar: 532 reports
• Bi-polar: 532 reports
• Bipolar 1: 108 reports
• Bipolar disorder: 532 reports
• Blood cholesterol abnormal: 660 reports
• Blood cholesterol increased: 660 reports
• Blood pressure abnormal: 214 reports
• Blood pressure - high: 777 reports
• Blood pressure increased: 777 reports
• Blood triglycerides abnormal: 660 reports
• Blood triglycerides increased: 660 reports
• Bronchial asthma: 335 reports
• Cancer - prostate: 206 reports
• Cannot sleep: 485 reports
• Can't sleep: 485 reports
• Can't stay wake: 103 reports
• Cardiac disorder: 153 reports
• Cataplexy: 372 reports
• Cessation of smoking: 149 reports
• Chronic asthma: 335 reports
• Chronic obstructive airway disease: 111 reports
• Chronic obstructive pulmonary disease: 111 reports
• Constipation: 105 reports
• Copd: 111 reports
• Crohns: 215 reports
• Crohn's disease: 215 reports
• Crohns disease: 215 reports
• Crohn's disease aggravated: 215 reports
• Daytime sleep disorder: 751 reports
• Depression: 1,613 reports
• Depression aggravated: 1,613 reports
• Depression - major: 245 reports
• Diabetes: 270 reports
• Diabetes mellitus: 271 reports
• Diabetes mellitus management: 270 reports
• Diabetes - type 2: 153 reports
• Diabetic type 2: 153 reports
• Dm: 270 reports
• Drug dependence: 154 reports
• Dyslipidemia: 660 reports
• Dyspepsia: 193 reports
• Dyssomnia: 485 reports
• Excessive sleepiness: 429 reports
• Exercise-induced asthma: 335 reports
• Familial primary pulmonary hypertension: 291 reports
• Feeling uptight: 767 reports
• Fibromyalgia: 354 reports
• Fibromyalgia syndrome: 354 reports
• Fibromyositis: 354 reports
• Fibrositis: 354 reports
• Gastroesophageal reflux disease: 450 reports
• Gastro-oesophageal reflux disease: 450 reports
• Gastrooesophageal reflux disease: 450 reports
• Gerd: 450 reports
• Gerds: 450 reports
• Glucose test: 204 reports
• Granulomatous ileocolitis: 215 reports
• Hbp: 777 reports
• Headache: 113 reports
• Headaches: 113 reports
• Heartburn: 450 reports
• Heartburn - chronic: 450 reports
• Hepatitis c: 120 reports
• High blood cholesterol: 660 reports
• High blood cholesterol and triglycerides: 660 reports
• High blood pressure: 777 reports
• High cholesterol: 660 reports
• Htn: 777 reports
• Hypercholesterolaemia: 660 reports
• Hypercholesterolemia: 660 reports
• Hyperlipidemia: 660 reports
• Hyperlipoproteinemia: 660 reports
• Hypertension: 779 reports
• Hypertension aggravated: 779 reports
• Hypothyroid: 246 reports
• Hypothyroidism: 246 reports
• Hypothyroids: 246 reports
• Hypothyroidy: 246 reports
• Inability to sleep: 485 reports
• Indigestion: 193 reports
• Inflammatory bowel disease - crohn's disease: 215 reports
• Insomnia: 485 reports
• Insomnia concerns: 485 reports
• Insomnia exacerbated: 485 reports
• Insomnolence: 485 reports
• Jitters: 767 reports
• Joint inflammation: 232 reports
• Joint pain: 113 reports
• Ldl/hdl ratio increased: 660 reports
• Lipid disorders: 660 reports
• Lipid test: 660 reports
• Lipoprotein test: 660 reports
• Lower cholesterol: 472 reports
• Low thyroid: 246 reports
• Major depression: 245 reports
• Major depressive disorder: 246 reports
• Migraine: 258 reports
• Migraines: 258 reports
• Ms: 1,068 reports
• Ms hug: 1,068 reports
• Multiple myeloma: 219 reports
• Multiple sclerosis: 1,068 reports
• Muscle spasm: 286 reports
• Muscle spasms: 286 reports
• Myofascial pain syndrome: 354 reports
• Myxedema: 246 reports
• Narcolepsy: 751 reports
• Nausea: 192 reports
• Neck pain: 118 reports
• Nerve pain: 240 reports
• Neuralgia: 240 reports
• Neuropathy peripheral: 170 reports
• Niddm: 153 reports
• Nocturnal myoclonus: 1,066 reports
• Non-cardiac chest pain: 450 reports
• Osteopenia: 295 reports
• Osteoporosis: 948 reports
• Pain: 978 reports
• Pain management: 976 reports
• Pain - neck: 118 reports
• Pain relief: 976 reports
• Panic attack: 131 reports
• Panic attacks: 131 reports
• Panic disorder: 131 reports
• Paralysis agitans: 408 reports
• Parkinson: 115 reports
• Parkinsonism: 408 reports
• Parkinsons: 115 reports
• Parkinson's disease: 409 reports
• Parkinson's disease aggravated: 409 reports
• Periodic limb movement disorder: 1,066 reports
• Plaque psoriasis: 167 reports
• Plasma cell myeloma: 219 reports
• Plmd: 1,066 reports
• Postherpetic neuralgia: 240 reports
• Post traumatic stress disorder: 175 reports
• Post-traumatic stress disorder: 107 reports
• Primary pulmonary hypertension: 291 reports
• Prostate cancer: 206 reports
• Psoriasis: 167 reports
• Psoriasis aggravated: 167 reports
• Psoriatic arthropathy: 150 reports
• Psoriatic arthropathy aggravated: 150 reports
• Psychotic disorder: 166 reports
• Ptsd: 175 reports
• Pulmonary arterial hypertension: 291 reports
• Pulmonary hypertension: 106 reports
• Pyrosis: 450 reports
• Quit smoking: 149 reports
• Ra: 741 reports
• Reduce cholesterol: 571 reports
• Reflux: 450 reports
• Reflux esophagitis: 450 reports
• Regional enteritis: 215 reports
• Relapsing-remitting multiple sclerosis: 134 reports
• Restless leg: 1,513 reports
• Restless legs: 1,450 reports
• Restless legs syndrome: 1,450 reports
• Restless leg syndrome: 1,450 reports
• Rheumatoid arthritis: 741 reports
• Rls: 1,513 reports
• Schizophrenia: 201 reports
• Sedation: 103 reports
• Sleep aid: 485 reports
• Sleep disorder: 429 reports
• Sleep disorder due to a general medical condition: 429 reports
• Sleep disorder due to general medical condition, insomnia type: 429 reports
• Sleep disorder therapy: 429 reports
• Sleeping: 485 reports
• Sleeping difficulty: 485 reports
• Sleep issues: 485 reports
• Sleeplessness: 485 reports
• Sleep - too much: 429 reports
• Smoker: 149 reports
• Smoking and smokeless tobacco: 149 reports
• Smoking cessation: 149 reports
• Smoking cessation therapy: 149 reports
• Stomach upset: 193 reports
• Stop smoking: 149 reports
• Stress: 767 reports
• Stress and anxiety: 767 reports
• Tension: 767 reports
• Thin bones: 916 reports
• Thyroid: 119 reports
• Thyroid diseases: 153 reports
• Thyroid disorder: 153 reports
• Thyroide: 153 reports
• Thyroid function test abnormal: 153 reports
• Tobacco abuse: 149 reports
• Tobacco user: 149 reports
• Type 2 diabetes: 153 reports
• Type 2 diabetes mellitus: 153 reports
• Underactive thyroid: 246 reports
• Under active thyroids: 246 reports
• Unipolar depression: 245 reports
• Wakefulness: 485 reports

All the conditions that are associated with Restless leg syndrome:

• Restless leg syndrome (1,763 conditions)

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