Metronidazole and Clostridium difficile colitis - a phase IV clinical study of FDA data
Summary:
Clostridium difficile colitis is found among people who take Metronidazole, especially for people who are female, 60+ old, have been taking the drug for < 1 month.
The phase IV clinical study analyzes which people take Metronidazole and have Clostridium difficile colitis. It is created by eHealthMe based on reports of 49,154 people who have side effects when taking Metronidazole from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
49,154 people reported to have side effects when taking Metronidazole.
Among them, 577 people (1.17%) have Clostridium difficile colitis.
What is Metronidazole?
Metronidazole has active ingredients of metronidazole. It is often used in vaginitis bacterial. eHealthMe is studying from 50,552 Metronidazole users for its effectiveness, alternative drugs and more.
What is Clostridium difficile colitis?
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection) is found to be associated with 2,131 drugs and 1,724 conditions by eHealthMe.
Number of Metronidazole and Clostridium difficile colitis reports submitted per year:

Time on Metronidazole when people have Clostridium difficile colitis *:
Gender of people who have Clostridium difficile colitis when taking Metronidazole*:
Age of people who have Clostridium difficile colitis when taking Metronidazole *:
Common drugs people take besides Metronidazole *:
Common side effects people have besides Clostridium difficile colitis *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Metronidazole and have Clostridium difficile colitis?
Check whether Clostridium difficile colitis is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Clostridium difficile colitis and when was it recovered:
Expand to all the drugs that have ingredients of metronidazole:
Alternative drugs to, pros and cons of Metronidazole:
- Metronidazole (50,552 reports)
Common Metronidazole side effects:
- Drug ineffective: 3,390 reports
- Diarrhea: 3,370 reports
- Fever: 2,799 reports
- Pain: 2,637 reports
- Nausea and vomiting: 2,491 reports
- Fatigue (feeling of tiredness): 2,387 reports
- Rashes (redness): 2,345 reports
- Stress and anxiety: 2,336 reports
Browse all side effects of Metronidazole:
a b c d e f g h i j k l m n o p q r s t u v w x y zClostridium difficile colitis treatments and more:
- Clostridium difficile colitis (12,168 reports)
COVID vaccines that are related to Clostridium difficile colitis:
- Clostridium difficile colitis in Moderna COVID Vaccine
- Clostridium difficile colitis in Pfizer BioNTech Covid Vaccine
- Clostridium difficile colitis in Johnson and Johnson Covid Vaccine
Common drugs associated with Clostridium difficile colitis:
- Prednisone: 1,229 reports
- Methotrexate: 743 reports
- Cyclophosphamide: 735 reports
- Aspirin: 730 reports
- Omeprazole: 579 reports
- Metronidazole: 577 reports
- Etoposide: 560 reports
- Cytarabine: 544 reports
- Furosemide: 501 reports
- Revlimid: 492 reports
All the drugs that are associated with Clostridium difficile colitis:
- Clostridium difficile colitis (2,131 drugs)
Common conditions associated with Clostridium difficile colitis:
- Multiple myeloma: 766 reports
- High blood pressure: 709 reports
- Pain: 463 reports
- Acute lymphocytic leukemia (all): 402 reports
- Crohn's disease: 358 reports
- Urinary tract infection: 338 reports
- Multiple sclerosis: 332 reports
- Osteoporosis: 317 reports
All the conditions that are associated with Clostridium difficile colitis:
- Clostridium difficile colitis (1,724 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on metronidazole (the active ingredients of Metronidazole) and Metronidazole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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