Milk of magnesia and Knee joint replacement - a phase IV clinical study of FDA data

Summary:

Knee joint replacement is found among people who take Milk of magnesia, especially for people who are female, 60+ old.

The phase IV clinical study analyzes which people take Milk of magnesia and have Knee joint replacement. It is created by eHealthMe based on reports of 8,770 people who have side effects when taking Milk of magnesia from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Oct, 01, 2022

8,770 people reported to have side effects when taking Milk of magnesia.
Among them, 13 people (0.15%) have Knee joint replacement.


What is Milk of magnesia?

Milk of magnesia has active ingredients of magnesium hydroxide. It is often used in constipation. eHealthMe is studying from 8,988 Milk of magnesia users for its effectiveness, alternative drugs and more.

What is Knee joint replacement?

Knee joint replacement is found to be associated with 1,739 drugs and 1,074 conditions by eHealthMe.

Number of Milk of magnesia and Knee joint replacement reports submitted per year:

Could Milk of magnesia cause Knee joint replacement?

Gender of people who have Knee joint replacement when taking Milk of magnesia *:

  • female: 69.23 %
  • male: 30.77 %

Age of people who have Knee joint replacement when taking Milk of magnesia *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 18.18 %
  • 60+: 81.82 %

Common drugs people take besides Milk of magnesia *:

  1. Coumadin: 10 people, 76.92%
  2. Hydrochlorothiazide: 9 people, 69.23%
  3. Effexor: 9 people, 69.23%
  4. Synthroid: 8 people, 61.54%
  5. Xanax: 8 people, 61.54%
  6. Ambien: 7 people, 53.85%
  7. Protonix: 6 people, 46.15%
  8. Centrum: 6 people, 46.15%
  9. Lisinopril: 6 people, 46.15%
  10. Nexium: 5 people, 38.46%

Common side effects people have besides Knee joint replacement *:

  1. High Blood Pressure: 7 people, 53.85%
  2. Dizziness: 7 people, 53.85%
  3. Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 7 people, 53.85%
  4. Weakness: 6 people, 46.15%
  5. Mitral Valve Incompetence (inefficient heart valve): 6 people, 46.15%
  6. Emotional Distress: 6 people, 46.15%
  7. Stress And Anxiety: 6 people, 46.15%
  8. Injury: 6 people, 46.15%
  9. Hypophagia (reduced food intake): 6 people, 46.15%
  10. Breathing Difficulty: 6 people, 46.15%

Common conditions people have *:

  1. Osteoporosis (bones weak and more likely to break): 4 people, 30.77%
  2. Neoplasm Malignant (cancer tumour): 4 people, 30.77%
  3. Metastases To Spine (cancer spreads to spine): 4 people, 30.77%
  4. Lung Neoplasm (tumour of lung): 4 people, 30.77%
  5. Calcium Deficiency (lack of calcium): 4 people, 30.77%
  6. Depression: 3 people, 23.08%
  7. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 7.69%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.69%
  9. Cardiac Disorder: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Milk of magnesia and have Knee joint replacement?

Check whether Knee joint replacement is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



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How severe was Knee joint replacement and when was it recovered:

Expand to all the drugs that have ingredients of magnesium hydroxide:

Alternative drugs to, pros and cons of Milk of magnesia:

Common Milk of magnesia side effects:

Browse all side effects of Milk of magnesia:

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Knee joint replacement treatments and more:

COVID vaccines that are related to Knee joint replacement:

Common drugs associated with Knee joint replacement:

All the drugs that are associated with Knee joint replacement:

Common conditions associated with Knee joint replacement:

All the conditions that are associated with Knee joint replacement:

How the study uses the data?

The study uses data from the FDA. It is based on magnesium hydroxide (the active ingredients of Milk of magnesia) and Milk of magnesia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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