Mirena and Chloasma - from FDA reports

Chloasma is found among people who take Mirena, especially for people who are 40-49 old , have been taking the drug for 2 - 5 years, also take medication Mefenamic Acid, and have Heavy or prolong menstrual bleeding. This review analyzes which people have Chloasma with Mirena. It is created by eHealthMe based on reports of 98,847 people who have side effects when taking Mirena from FDA , and is updated regularly.

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA since 1977. Our original studies have been referenced on 400+ peer-reviewed medical publications, including: The Lancet, and Mayo Clinic Proceedings.

On Mar, 24, 2018

98,847 people reported to have side effects when taking Mirena.
Among them, 51 people (0.05%) have Chloasma

Number of reports submitted per year:

Could Mirena cause Chloasma?

Time on Mirena when people have Chloasma *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 20 %
  • 1 - 2 years: 30 %
  • 2 - 5 years: 30 %
  • 5 - 10 years: 20 %
  • 10+ years: 0.0 %

Age of people who have Chloasma when taking Mirena *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 46.88 %
  • 40-49: 50.0 %
  • 50-59: 3.12 %
  • 60+: 0.0 %

Top conditions involved for these people *:

  • Heavy Or Prolong Menstrual Bleeding: 12 people, 23.53%
  • Menstruation Irregular: 1 person, 1.96%
  • Intra-Uterine Contraceptive Device: 1 person, 1.96%
  • Asthma: 1 person, 1.96%

Top co-used drugs for these people *:

  • Mesalamine: 2 people, 3.92%
  • Mefenamic Acid: 2 people, 3.92%
  • Plaquenil: 1 person, 1.96%
  • Differin: 1 person, 1.96%
  • Coumadin: 1 person, 1.96%

Top other side effects for these people *:

  • Abdominal Distension: 4 people, 7.84%
  • Weight Increased: 3 people, 5.88%
  • Depression: 3 people, 5.88%
  • Amenorrhea (absence of a menstrual period in a woman of reproductive age): 3 people, 5.88%
  • Depressed Mood: 2 people, 3.92%

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Subscribe to the study: get notified of updates to the study.

Want to find out more about the FDA reports used in the study? You can request them from FDA.

Do you take Mirena and have Chloasma?

Related tests

We suggest these affordable tests for self monitoring. You can order them and receive results on eHealthMe. No doctor referral or insurance necessary.

Related studies


Mirena has active ingredients of levonorgestrel. It is often used in birth control. (latest outcomes from Mirena 100,169 users)


Chloasma (a patchy brown or dark brown skin discoloration in pregnancy) has been reported by people with birth control, heavy or prolong menstrual bleeding, hormone replacement therapy, multiple sclerosis, depression (latest reports from 647 Chloasma patients).

Drugs that are associated with Chloasma
Chloasma (279 drugs)
Could your condition cause Chloasma
Chloasma (162 conditions)
Expand the study to include all drugs with the same ingredients
Chloasma and drugs with ingredients of levonorgestrel. (55 reports)
Expand the study to include reports from both FDA and eHealthMe
Chloasma and Mirena from FDA and eHealthMe reports (55 reports)
Mirena side effects
Browse all side effects of Mirena
a b c d e f g h i j k l m n o p q r s t u v w x y z

Analysis tools (to study 684 million drug outcomes from FDA)

  • Check symptoms - identify the cause of a symptom: from a drug or from a condition?
  • Check drugs - find out common side effects or drug interactions of my drugs.
  • Compare drugs - compare the side effects and efficacy of multiple drugs side by side.

What would happen?

Predict new side effects and undetected conditions when you take Mirena and have Chloasma

You are not alone. Join our personalized support groups:

Can you answer these questions

More questions for: Mirena, Chloasma

You may be interested in these posts

More posts for: Mirena, Chloasma

Recent updates

General studies
Active Support Groups
Recent Predictions
Personalized studies

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.