Mirena and Chronic thyroiditis (hashimoto's disease) - a phase IV clinical study of FDA data

Summary:

Chronic thyroiditis (hashimoto's disease) is found among people who take Mirena, especially for people who are female, 30-39 old, have been taking the drug for 5 - 10 years.

The phase IV clinical study analyzes which people take Mirena and have Chronic thyroiditis (hashimoto's disease). It is created by eHealthMe based on reports of 135,455 people who have side effects when taking Mirena from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Sep, 25, 2022

135,455 people reported to have side effects when taking Mirena.
Among them, 64 people (0.05%) have Chronic thyroiditis (hashimoto's disease).


What is Mirena?

Mirena has active ingredients of levonorgestrel. It is often used in birth control. eHealthMe is studying from 137,076 Mirena users for its effectiveness, alternative drugs and more.

What is Chronic thyroiditis (hashimoto's disease)?

Chronic thyroiditis (hashimoto's disease) is found to be associated with 1,174 drugs and 896 conditions by eHealthMe.

Number of Mirena and Chronic thyroiditis (hashimoto's disease) reports submitted per year:

Could Mirena cause Chronic thyroiditis (hashimoto's disease)?

Time on Mirena when people have Chronic thyroiditis (hashimoto's disease) *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 13.64 %
  • 6 - 12 months: 4.55 %
  • 1 - 2 years: 9.09 %
  • 2 - 5 years: 27.27 %
  • 5 - 10 years: 36.36 %
  • 10+ years: 9.09 %

Gender of people who have Chronic thyroiditis (hashimoto's disease) when taking Mirena *:

  • female: 98.44 %
  • male: 1.56 %

Age of people who have Chronic thyroiditis (hashimoto's disease) when taking Mirena *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 20.0 %
  • 30-39: 51.43 %
  • 40-49: 22.86 %
  • 50-59: 5.71 %
  • 60+: 0.0 %

Common drugs people take besides Mirena *:

  1. Synthroid: 3 people, 4.69%
  2. Magnesium: 3 people, 4.69%
  3. Levothyroxine Sodium: 2 people, 3.12%
  4. Chromium: 2 people, 3.12%
  5. Coenzyme Q10: 2 people, 3.12%
  6. Enbrel: 2 people, 3.12%
  7. Kyleena: 2 people, 3.12%
  8. Acidophilus: 2 people, 3.12%
  9. Vitamin D3: 2 people, 3.12%
  10. Tyrosine: 2 people, 3.12%

Common side effects people have besides Chronic thyroiditis (hashimoto's disease) *:

  1. Weight Increased: 19 people, 29.69%
  2. Loss Of Libido (loss of sexual urge): 14 people, 21.88%
  3. Migraine (headache): 13 people, 20.31%
  4. Acne (skin problems that cause pimples): 13 people, 20.31%
  5. Depression: 13 people, 20.31%
  6. Hair Loss: 12 people, 18.75%
  7. Dizziness: 12 people, 18.75%
  8. Fatigue (feeling of tiredness): 12 people, 18.75%
  9. Feeling Abnormal: 11 people, 17.19%
  10. Panic Disorder: 11 people, 17.19%

Common conditions people have *:

  1. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 4.69%
  2. Menstrual Disorder (disease of menstrual cycle): 2 people, 3.12%
  3. Genital Haemorrhage (bleeding from genital): 2 people, 3.12%
  4. Abdominal Pain: 2 people, 3.12%
  5. Thyroid Diseases: 1 person, 1.56%
  6. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 1.56%
  7. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 1.56%
  8. Osteopenia (a condition where bone mineral density is lower than normal): 1 person, 1.56%
  9. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 1.56%
  10. High Blood Pressure: 1 person, 1.56%

* Approximation only. Some reports may have incomplete information.

Do you take Mirena and have Chronic thyroiditis (hashimoto's disease)?

Check whether Chronic thyroiditis (hashimoto's disease) is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related studies

How severe was Chronic thyroiditis (hashimoto's disease) and when was it recovered:

Expand to all the drugs that have ingredients of levonorgestrel:

Alternative drugs to, pros and cons of Mirena:

Common Mirena side effects:

Browse all side effects of Mirena:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Chronic thyroiditis (hashimoto's disease) treatments and more:

COVID vaccines that are related to Chronic thyroiditis (hashimoto's disease):

Common drugs associated with Chronic thyroiditis (hashimoto's disease):

All the drugs that are associated with Chronic thyroiditis (hashimoto's disease):

Common conditions associated with Chronic thyroiditis (hashimoto's disease):

All the conditions that are associated with Chronic thyroiditis (hashimoto's disease):

How the study uses the data?

The study uses data from the FDA. It is based on levonorgestrel (the active ingredients of Mirena) and Mirena (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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