Mirena and Melasma - from FDA reports

Melasma is found among people who take Mirena, especially for people who are 30-39 old , have been taking the drug for 2 - 5 years, also take medication Mefenamic Acid, and have Heavy or prolong menstrual bleeding. This study is created by eHealthMe based on reports of 110,663 people who have side effects when taking Mirena from FDA, and is updated regularly.

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On Oct, 16, 2018

110,663 people reported to have side effects when taking Mirena.
Among them, 67 people (0.06%) have Melasma

Number of reports submitted per year:

Could Mirena cause Melasma?

Time on Mirena when people have Melasma *:

Age of people who have Melasma when taking Mirena *:

Top conditions involved for these people *:

  1. Heavy Or Prolong Menstrual Bleeding: 13 people, 19.40%
  2. Menstruation Irregular: 1 person, 1.49%
  3. Intra-Uterine Contraceptive Device: 1 person, 1.49%
  4. Asthma: 1 person, 1.49%

Top co-used drugs for these people *:

  1. Mesalamine: 2 people, 2.99%
  2. Mefenamic Acid: 2 people, 2.99%
  3. Vyvanse: 1 person, 1.49%
  4. Vitamin D3: 1 person, 1.49%
  5. Spironolactone: 1 person, 1.49%

Click here to view more results or personalize the results to your gender and age

Top other side effects for these people *:

  1. Depression: 10 people, 14.93%
  2. Abdominal Distension: 8 people, 11.94%
  3. Fatigue (feeling of tiredness): 7 people, 10.45%
  4. Weight Increased: 7 people, 10.45%
  5. Hair Loss: 6 people, 8.96%

Click here to view more results or personalize the results to your gender and age

* Approximation only. Some reports may have incomplete information.

FDA reports used in this study

Do you have Melasma while taking Mirena?

You are not alone:

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Mirena has active ingredients of levonorgestrel. It is often used in birth control. (latest outcomes from Mirena 111,985 users)


Melasma (the mask of pregnancy when present in pregnant women) is a tan or dark skin discoloration) has been reported by people with birth control, heavy or prolong menstrual bleeding, multiple sclerosis, hormone replacement therapy, depression (latest reports from 720 Melasma patients).

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What would happen?

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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